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Title

Synthesis and physicochemical properties of antianemic iron and calcium complexes with sodium polygalacturonate.

Authors

Minzanova, S.; Khamatgalimov, A.; Ryzhkina, I.; Murtazina, L.; Mironova, L.; Kadirov, M.; Vyshtakalyuk, A.; Milyukov, V.; Mironov, V.

Abstract

New stable water-soluble metal complexes of citrus pectin (sodium polygalacturonate, PG-Na) with biogenic microelements (Ca and Fe) that we synthesized were characterized by infrared spectroscopy, dynamic light scattering, and atomic force microscopy. The temperature dependence of the mass of PG-Na, PG-NaFe, and PG-NaFeCa samples was studied by simultaneous thermal analysis. Water was found to be the major component of the gas phase in the first stage of mass loss of PG-NaFe and PG-NaFeCa, while the second stage involves decarboxylation and decomposition. The stimulating action of PG-NaFe and PG-NaFeCa on hematopoiesis in outbred rats during growing period, manifested as more than 10% increase in the hemoglobin concentration, was demonstrated.

Subjects

IRON compound synthesis; CALCIUM compounds; WATER-soluble polymers; METAL complexes; POLYGALACTURONASE; ATOMIC force microscopy

Publication

Doklady Physical Chemistry, 2016, Vol 467, Issue 2, p45

ISSN

0012-5016

Publication type

Academic Journal

DOI

10.1134/S0012501616040011

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