Relationship between self-organization and biological activity of highly diluted solutions of a tetrahydrazide tetrathiacalix[4]arene derivative.

Ryzhkina, I.; Kiseleva, Yu.; Mishina, O.; Voloshina, A.; Kulik, N.; Valitova, Yu.; Sudakova, S.; Podyachev, S.; Zobov, V.; Konovalov, A.

In the course of systematic study of self-organization and properties of diluted solutions of biologically active compounds (BACs), an unknown phenomenon has been discovered. Using a complex of physicochemical methods, it has been shown for the first time that diluted aqueous solutions of many BACs in a wide range of calculated concentrations (10-10 mol/L), prepared by serial tenfold dilution from a stock solution, are self-organized disperse systems in which the disperse phase is represented by nanosized molecular ensembles (up to 400 nm) denominated nanoassociates [1].

BIOACTIVE compounds; ATOMIC force microscopy; AQUEOUS solutions; ELECTROMAGNETIC fields; LIGHT scattering

Doklady Physical Chemistry, 2015, Vol 464, Issue 2, p251

0012-5016

Academic Journal

10.1134/S0012501615100085