Works matching IS 19466234 AND DT 2017

Results: 248
    1

    Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 421, p. 1, doi. 10.1126/scitranslmed.aai8753
    By:
    • Riga, Danai;
    • Kramvis, Ioannis;
    • Koskinen, Maija K.;
    • van Bokhoven, Pieter;
    • van der Harst, Johanneke E.;
    • Heistek, Tim S.;
    • Timmerman, A. Jaap;
    • van Nierop, Pim;
    • van der Schors, Roel C.;
    • Pieneman, Anton W.;
    • de Weger, Anouk;
    • van Mourik, Yvar;
    • Schoffelmeer, Anton N. M.;
    • Mansvelder, Huib D.;
    • Meredith, MRhiannon M.;
    • Hoogendijk, Witte J. G.;
    • Smit, August B.;
    • Spijker, Sabine
    Publication type:
    Article
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    Vaccination of dogs in an African city interrupts rabies transmission and reduces human exposure.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 421, p. 1, doi. 10.1126/scitranslmed.aaf6984
    By:
    • Zinsstag, Jakob;
    • Lechenne, Monique;
    • Laager, Mirjam;
    • Mindekem, Rolande;
    • Naïssengar, Service;
    • Oussiguéré, Assandi;
    • Bidjeh, Kebkiba;
    • Rives, Germain;
    • Tessier, Julie;
    • Madjaninan, Seraphin;
    • Ouagal, Mahamat;
    • Moto, Daugla D.;
    • Alfaroukh, Idriss O.;
    • Muthiani, Yvonne;
    • Traoré, Abdallah;
    • Hattendorf, Jan;
    • Lepelletier, Anthony;
    • Kergoat, Lauriane;
    • Bourhy, Hervé;
    • Dacheux, Laurent
    Publication type:
    Article
    6

    Durability and correlates of vaccine protection against Zika virus in rhesus monkeys.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aao4163
    By:
    • Abbink, Peter;
    • Larocca, Rafael A.;
    • Visitsunthorn, Kittipos;
    • Boyd, Michael;
    • De La Barrera, Rafael A.;
    • Gromowski, Gregory D.;
    • Kirilova, Marinela;
    • Peterson, Rebecca;
    • Zhenfeng Li;
    • Nanayakkara, Ovini;
    • Nityanandam, Ramya;
    • Mercado, Noe B.;
    • Borducchi, Erica N.;
    • Chandrashekar, Abishek;
    • Jetton, David;
    • Mojta, Shanell;
    • Gandhi, Priya;
    • LeSuer, Jake;
    • Khatiwada, Shreeya;
    • Lewis, Mark G.
    Publication type:
    Article
    7

    A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 421, p. 1, doi. 10.1126/scitranslmed.aai7635
    By:
    • Ryan, Katie J.;
    • White, Charles C.;
    • Patel, Kruti;
    • Xu, Jishu;
    • Olah, Marta;
    • Replogle, Joseph M.;
    • Frangieh, Michael;
    • Cimpean, Maria;
    • Winn, Phoebe;
    • McHenry, Allison;
    • Kaskow, Belinda J.;
    • Chan, Gail;
    • Cuerdon, Nicole;
    • Bennett, David A.;
    • Boyd, Justin D.;
    • Imitola, Jaime;
    • Elyaman, Wassim;
    • De Jager, Philip L.;
    • Bradshaw, Elizabeth M.
    Publication type:
    Article
    8

    Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aal3765
    By:
    • Lagares, David;
    • Santos, Alba;
    • Grasberger, Paula E.;
    • Fei Liu;
    • Probst, Clemens K.;
    • Rahimi, Rod A.;
    • Norihiko Sakai;
    • Kuehl, Tobias;
    • Ryan, Jeremy;
    • Bhola, Patrick;
    • Montero, Joan;
    • Kapoor, Mohit;
    • Baron, Murray;
    • Varelas, Xaralabos;
    • Tschumperlin, Daniel J.;
    • Letai, Anthony;
    • Tager, Andrew M.
    Publication type:
    Article
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    Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aah4985
    By:
    • Umanah, George K. E.;
    • Pignatelli, Marco;
    • Xiling Yin;
    • Rong Chen;
    • Crawford, Joshua;
    • Neifert, Stewart;
    • Scarffe, Leslie;
    • Behensky, Adam A.;
    • Guiberson, Noah;
    • Chang, Melissa;
    • Ma, Erica;
    • Jin Wan Kim;
    • Castro, Cibele C.;
    • Xiaobo Mao;
    • Li Chen;
    • Andrabi, Shaida A.;
    • Pletnikov, Mikhail V.;
    • Pulver, Ann E.;
    • Avramopoulos, Dimitrios;
    • Bonci, Antonello
    Publication type:
    Article
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    A randomized controlled safety/efficacy trial of therapeutic vaccination in HIV-infected individuals who initiated antiretroviral therapy early in infection.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aan8848
    By:
    • Sneller, Michael C.;
    • Justement, J. Shawn;
    • Gittens, Kathleen R.;
    • Petrone, Mary E.;
    • Clarridge, Katherine E.;
    • Proschan, Michael A.;
    • Kwan, Richard;
    • Shi, Victoria;
    • Blazkova, Jana;
    • Refsland, Eric W.;
    • Morris, Daryl E.;
    • Cohen, Kristen W.;
    • McElrath, M. Juliana;
    • Rong Xu;
    • Egan, Michael A.;
    • Eldridge, John H.;
    • Benko, Erika;
    • Kovacs, Colin;
    • Moir, Susan;
    • Tae-Wook Chun
    Publication type:
    Article
    13

    A degradation fragment of type X collagen is a real-time marker for bone growth velocity.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aan4669
    By:
    • Coghlan, Ryan F.;
    • Oberdorf, Jon A.;
    • Sienko, Susan;
    • Aiona, Michael D.;
    • Boston, Bruce A.;
    • Connelly, Kara J.;
    • Bahney, Chelsea;
    • LaRouche, Jeremie;
    • Almubarak, Sarah M.;
    • Coleman, Daniel T.;
    • Girkontaite, Irute;
    • von der Mark, Klaus;
    • Lunstrum, Gregory P.;
    • Horton, William A.
    Publication type:
    Article
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    Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aam6764
    By:
    • Tietjen, Gregory T.;
    • Hosgood, Sarah A.;
    • DiRito, Jenna;
    • Jiajia Cui;
    • Deep, Deeksha;
    • Song, Eric;
    • Kraehling, Jan R.;
    • Piotrowski-Daspit, Alexandra S.;
    • Kirkiles-Smith, Nancy C.;
    • Al-Lamki, Rafia;
    • Thiru, Sathia;
    • Bradley, J. Andrew;
    • Saeb-Parsy, Kourosh;
    • Bradley, John R.;
    • Nicholson, Michael L.;
    • Saltzman, W. Mark;
    • Pober, Jordan S.
    Publication type:
    Article
    16

    PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aal2332
    By:
    • Dickey, Audrey S.;
    • Sanchez, Dafne N.;
    • Arreola, Martin;
    • Sampat, Kunal R.;
    • Weiwei Fan;
    • Arbez, Nicolas;
    • Akimov, Sergey;
    • Van Kanegan, Michael J.;
    • Ohnishi, Kohta;
    • Gilmore-Hall, Stephen K.;
    • Flores, April L.;
    • Nguyen, Janice M.;
    • Lomas, Nicole;
    • Hsu, Cynthia L.;
    • Lo, Donald C.;
    • Ross, Christopher A.;
    • Masliah, Eliezer;
    • Evans, Ronald M.;
    • La Spada, Albert R.
    Publication type:
    Article
    17

    Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aao6298
    By:
    • Ken Chen;
    • Zaicheng Xu;
    • Yukai Liu;
    • Zhen Wang;
    • Yu Li;
    • Xuefei Xu;
    • Caiyu Chen;
    • Tianyang Xia;
    • Qiao Liao;
    • Yonggang Yao;
    • Cindy Zeng;
    • Duofen He;
    • Yongjian Yang;
    • Tao Tan;
    • Jianxun Yi;
    • Jingsong Zhou;
    • Hua Zhu;
    • Jianjie Ma;
    • Chunyu Zeng
    Publication type:
    Article
    18

    Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aao1632
    By:
    • Mayer, Balázs;
    • Németh, Krisztián;
    • Krepuska, Miklós;
    • Myneni, Vamsee D.;
    • Maric, Dragan;
    • Tisdale, John F.;
    • Hsieh, Matthew M.;
    • Naoya Uchida;
    • Heon-Jin Lee;
    • Nemeth, Michael J.;
    • Holmbeck, Kenn;
    • Tom Noguchi, Constance;
    • Rogers, Heather;
    • Dey, Soumyadeep;
    • Hansen, Arne;
    • Jeffrey Hong;
    • Ian Chow;
    • Key, Sharon;
    • Szalayova, Ildikó;
    • Pagani, Jerome
    Publication type:
    Article
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    BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aam7816
    By:
    • Fard, Maryam K.;
    • van der Meer, Franziska;
    • Sánchez, Paula;
    • Cantuti-Castelvetri, Ludovico;
    • Mandad, Sunit;
    • Jäkel, Sarah;
    • Fornasiero, Eugenio F.;
    • Schmitt, Sebastian;
    • Ehrlich, Marc;
    • Starost, Laura;
    • Kuhlmann, Tanja;
    • Sergiou, Christina;
    • Schultz, Verena;
    • Wrzos, Claudia;
    • Brück, Wolfgang;
    • Urlaub, Henning;
    • Dimou, Leda;
    • Stadelmann, Christine;
    • Simons, Mikael
    Publication type:
    Article
    21

    What evidence do we need for biomarker qualification?

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aal4599
    By:
    • Leptak, Chris;
    • Menetski, Joseph P.;
    • Wagner, John A.;
    • Aubrecht, Jiri;
    • Brady, Linda;
    • Brumfield, Martha;
    • Chin, William W.;
    • Hoffmann, Steve;
    • Kelloff, Gary;
    • Lavezzari, Gabriela;
    • Ranganathan, Rajesh;
    • Sauer, John-Michael;
    • Sistare, Frank D.;
    • Zabka, Tanja;
    • Wholley, David
    Publication type:
    Article
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    Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aam8475
    By:
    • Shashar, Moshe;
    • Belghasem, Mostafa E.;
    • Matsuura, Shinobu;
    • Walker, Joshua;
    • Richards, Sean;
    • Alousi, Faisal;
    • Rijal, Keshab;
    • Kolachalama, Vijaya B.;
    • Balcells, Mercedes;
    • Minami Odagi;
    • Kazuo Nagasawa;
    • Henderson, Joel M.;
    • Gautam, Amitabh;
    • Rushmore, Richard;
    • Francis, Jean;
    • Kirchhofer, Daniel;
    • Kolandaivelu, Kumaran;
    • Sherr, David H.;
    • Edelman, Elazer R.;
    • Ravid, Katya
    Publication type:
    Article
    25

    Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aam7785
    By:
    • Orrú, Christina D.;
    • Jue Yuan;
    • Appleby, Brian S.;
    • Baiya Li;
    • Yu Li;
    • Winner, Dane;
    • Zerui Wang;
    • Yi-An Zhan;
    • Rodgers, Mark;
    • Rarick, Jason;
    • Wyza, Robert E.;
    • Joshi, Tripti;
    • Gong-Xian Wang;
    • Cohen, Mark L.;
    • Shulin Zhang;
    • Groveman, Bradley R.;
    • Petersen, Robert B.;
    • Ironside, James W.;
    • Quiñones-Mateu, Miguel E.;
    • Safar, Jiri G.
    Publication type:
    Article
    26

    Rescue of Pompe disease in mice by AAV-mediated liver delivery of secretable acid α-glucosidase.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aam6375
    By:
    • Puzzo, Francesco;
    • Colella, Pasqualina;
    • Biferi, Maria G.;
    • Bali, Deeksha;
    • Paulk, Nicole K.;
    • Vidal, Patrice;
    • Collaud, Fanny;
    • Simon-Sola, Marcelo;
    • Charles, Severine;
    • Hardet, Romain;
    • Leborgne, Christian;
    • Meliani, Amine;
    • Cohen-Tannoudji, Mathilde;
    • Astord, Stephanie;
    • Gjata, Bernard;
    • Sellier, Pauline;
    • van Wittenberghe, Laetitia;
    • Vignaud, Alban;
    • Boisgerault, Florence;
    • Barkats, Martine
    Publication type:
    Article
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    Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aam7828
    By:
    • Galleu, Antonio;
    • Riffo-Vasquez, Yanira;
    • Trento, Cristina;
    • Lomas, Cara;
    • Dolcetti, Luigi;
    • Tik Shing Cheung;
    • von Bonin, Malte;
    • Barbieri, Laura;
    • Halai, Krishma;
    • Ward, Sophie;
    • Ling Weng;
    • Chakraverty, Ronjon;
    • Lombardi, Giovanna;
    • Watt, Fiona M.;
    • Orchard, Kim;
    • Marks, David I.;
    • Apperley, Jane;
    • Bornhauser, Martin;
    • Walczak, Henning;
    • Bennett, Clare
    Publication type:
    Article
    30

    PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aam7543
    By:
    • Ben Nasr, Moufida;
    • Tezza, Sara;
    • D'Addio, Francesca;
    • Mameli, Chiara;
    • Usuelli, Vera;
    • Maestroni, Anna;
    • Corradi, Domenico;
    • Belletti, Silvana;
    • Albarello, Luca;
    • Becchi, Gabriella;
    • Fadini, Gian Paolo;
    • Schuetz, Christian;
    • Markmann, James;
    • Wasserfall, Clive;
    • Zon, Leonard;
    • Zuccotti, Gian Vincenzo;
    • Fiorina, Paolo
    Publication type:
    Article
    31

    Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aai9048
    By:
    • Pullamsetti, Soni Savai;
    • Kojonazarov, Baktybek;
    • Storn, Samantha;
    • Gall, Henning;
    • Salazar, Ylia;
    • Wolf, Janine;
    • Weigert, Andreas;
    • El-Nikhely, Nefertiti;
    • Ghofrani, Hossein Ardeschir;
    • Krombach, Gabriele A.;
    • Fink, Ludger;
    • Gattenlöhner, Stefan;
    • Rapp, Ulf R.;
    • Schermuly, Ralph Theo;
    • Grimminger, Friedrich;
    • Seeger, Werner;
    • Savai, Rajkumar
    Publication type:
    Article
    32

    A role for bacterial urease in gut dysbiosis and Crohn's disease.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aah6888
    By:
    • Ni, Josephine;
    • David Shen, Ting-Chin;
    • Chen, Eric Z.;
    • Bittinger, Kyle;
    • Bailey, Aubrey;
    • Roggiani, Manuela;
    • Sirota-Madi, Alexandra;
    • Friedman, Elliot S.;
    • Chau, Lillian;
    • Lin, Andrew;
    • Nissim, Ilana;
    • Scott, Justin;
    • Lauder, Abigail;
    • Hoffmann, Christopher;
    • Rivas, Gloriany;
    • Albenberg, Lindsey;
    • Baldassano, Robert N.;
    • Braun, Jonathan;
    • Xavier, Ramnik J.;
    • Clish, Clary B.
    Publication type:
    Article
    33

    Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 415, p. 1, doi. 10.1126/scitranslmed.aao4307
    By:
    • Nilsson, Monique B.;
    • Huiying Sun;
    • Lixia Diao;
    • Pan Tong;
    • Diane Liu;
    • Lerong Li;
    • Youhong Fan;
    • Poteete, Alissa;
    • Seung-Oe Lim;
    • Howells, Kathryn;
    • Haddad, Vincent;
    • Gomez, Daniel;
    • Hai Tran;
    • Armaiz Pena, Guillermo;
    • Sequist, Lecia V.;
    • Yang, James C.;
    • Jing Wang;
    • Kim, Edward S.;
    • Herbst, Roy;
    • Lee, J. Jack
    Publication type:
    Article
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    Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 415, p. 1, doi. 10.1126/scitranslmed.aam8574
    By:
    • van der Pol, Atze;
    • Gil, Andres;
    • Silljé, Herman H. W.;
    • Tromp, Jasper;
    • Ovchinnikova, Ekaterina S.;
    • Vreeswijk-Baudoin, Inge;
    • Hoes, Martijn;
    • Domian, Ibrahim J.;
    • van de Sluis, Bart;
    • van Deursen, Jan M.;
    • Voors, Adriaan A.;
    • van Veldhuisen, Dirk J.;
    • van Gilst, Wiek H.;
    • Berezikov, Eugene;
    • van der Harst, Pim;
    • de Boer, Rudolf A.;
    • Bischoff, Rainer;
    • van der Meer, Peter
    Publication type:
    Article
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    A precision therapy against cancers driven by KIT/PDGFRA mutations.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aao1690
    By:
    • Evans, Erica K.;
    • Gardino, Alexandra K.;
    • Kim, Joseph L.;
    • Hodous, Brian L.;
    • Shutes, Adam;
    • Davis, Alison;
    • Xing Julia Zhu;
    • Schmidt-Kittler, Oleg;
    • Wilson, Doug;
    • Wilson, Kevin;
    • DiPietro, Lucian;
    • Yulian Zhang;
    • Brooijmans, Natasja;
    • LaBranche, Timothy P.;
    • Wozniak, Agnieszka;
    • Gebreyohannes, Yemarshet K.;
    • Schöffski, Patrick;
    • Heinrich, Michael C.;
    • DeAngelo, Daniel J.;
    • Miller, Stephen
    Publication type:
    Article
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    Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 413, p. 1, doi. 10.1126/scitranslmed.aao4583
    By:
    • Michelakis, Evangelos D.;
    • Gurtu, Vikram;
    • Webster, Linda;
    • Barnes, Gareth;
    • Watson, Geoffrey;
    • Howard, Luke;
    • Cupitt, John;
    • Paterson, Ian;
    • Thompson, Richard B.;
    • Chow, Kelvin;
    • O'Regan, Declan P.;
    • Lan Zhao;
    • Wharton, John;
    • Kiely, David G.;
    • Kinnaird, Adam;
    • Boukouris, Aristeidis E.;
    • White, Chris;
    • Nagendran, Jayan;
    • Freed, Darren H.;
    • Wort, Stephen J.
    Publication type:
    Article
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    Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aam9078
    By:
    • Henssen, Anton G.;
    • Reed, Casie;
    • Eileen Jiang;
    • Garcia, Heathcliff Dorado;
    • von Stebut, Jennifer;
    • MacArthur, Ian C.;
    • Hundsdoerfer, Patrick;
    • Jun Hyun Kim;
    • de Stanchina, Elisa;
    • Kuwahara, Yasumichi;
    • Hosoi, Hajime;
    • Ganem, Neil J.;
    • Cruz, Filemon Dela;
    • Kung, Andrew L.;
    • Schulte, Johannes H.;
    • Petrini, John H.;
    • Kentsis, Alex
    Publication type:
    Article
    48

    Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 412, p. 1, doi. 10.1126/scitranslmed.aan8732
    By:
    • Yumei Xiong;
    • Walker, Kenneth;
    • Xiaoshan Min;
    • Hale, Clarence;
    • Thanhvien Tran;
    • Komorowski, Renee;
    • Yang, Jerry;
    • Davda, Jasmine;
    • Noi Nuanmanee;
    • Kemp, Dao;
    • Xiaozhen Wang;
    • Hantao Liu;
    • Miller, Silke;
    • Ki Jeong Lee;
    • Zhulun Wang;
    • Véniant, Murielle M.
    Publication type:
    Article
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    ALK is a therapeutic target for lethal sepsis.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 412, p. 1, doi. 10.1126/scitranslmed.aan5689
    By:
    • Ling Zeng;
    • Rui Kang;
    • Shan Zhu;
    • Xiao Wang;
    • Lizhi Cao;
    • Haichao Wang;
    • Billiar, Timothy R.;
    • Jianxin Jiang;
    • Daolin Tang
    Publication type:
    Article