Works matching AU Kannan, Natarajan

Results: 106

An atlas of bacterial serine-threonine kinases reveals functional diversity and key distinctions from eukaryotic kinases.

Published in:

Science Signaling, 2025, v. 18, n. 885, p. 1, doi. 10.1126/scisignal.adt8686

By:

O'Boyle, Brady;
Yeung, Wayland;
Lu, Jason D.;
Katiyar, Samiksha;
Yaron-Barir, Tomer M.;
Johnson, Jared L.;
Cantley, Lewis C.;
Kannan, Natarajan

Publication type:

Article

Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation.

Published in:

PLoS Biology, 2013, v. 11, n. 10, p. 1, doi. 10.1371/journal.pbio.1001680

By:

Meharena, Hiruy S.;
Chang, Philip;
Keshwani, Malik M.;
Oruganty, Krishnadev;
Nene, Aishwarya K.;
Kannan, Natarajan;
Taylor, Susan S.;
Kornev, Alexandr P.

Publication type:

Article

Structural and Functional Diversity of the Microbial Kinome.

Published in:

PLoS Biology, 2007, v. 5, n. 3, p. 0467, doi. 10.1371/journal.pbio.0050017

By:

Kannan, Natarajan;
Taylor, Susan S.;
Zhai, Yufeng;
Venter, J. Craig;
Manning, Gerard

Publication type:

Article

Visible Light Mediated Co‐Catalyzed Isocyanide Insertion with Sulfonyl Azide: Synthesis of Sulfonyl Carbamimidic Azide and Sulfonyl Aminotetrazole via Carbodiimide Intermediate.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 72, p. 1, doi. 10.1002/chem.202303153

By:

Ravindra, Sundaresan;
Natarajan, Kannan;
Padma Priya, Vetrivel R.;
Kataria, Ramesh;
Nandi, Ganesh Chandra

Publication type:

Article

Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.87958

By:

Venkat, Aarya;
Watterson, Grace;
Byrne, Dominic P.;
O'Boyle, Brady;
Shrestha, Safal;
Gravel, Nathan;
Fairweather, Emma E.;
Daly, Leonard A.;
Bunn, Claire;
Yeung, Wayland;
Aggarwal, Ishan;
Katiyar, Samiksha;
Eyers, Claire E.;
Eyers, Patrick A.;
Kannan, Natarajan

Publication type:

Article

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01657

By:

Natarajan, Kannan;
Jiang, Jiansheng;
May, Nathan A.;
Mage, Michael G.;
Boyd, Lisa F.;
McShan, Andrew C.;
Sgourakis, Nikolaos G.;
Bax, Ad;
Margulies, David H.

Publication type:

Article

Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis.

Published in:

European Journal of Immunology, 2008, v. 38, n. 12, p. 3339, doi. 10.1002/eji.200838584

By:

Levin, Ditza;
DiPaolo, Richard J.;
Brinster, Carine;
Revilleza, Maria Jamela R.;
Boyd, Lisa F.;
Teyton, Luc;
Natarajan, Kannan;
Mage, Michael G.;
Shevach, Ethan M.;
Margulies, David H.

Publication type:

Article

A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity.

Published in:

European Journal of Immunology, 2001, v. 31, n. 7, p. 2094, doi. 10.1002/1521-4141(200107)31:7<2094::AID-IMMU2094>3.0.CO;2-S

By:

McHugh, Rebecca S.;
Shevach, Ethan M.;
Margulies, David H.;
Natarajan, Kannan

Publication type:

Article

Post-thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase- reactive T cells.

Published in:

European Journal of Immunology, 1999, v. 29, n. 2, p. 669, doi. 10.1002/(SICI)1521-4141(199902)29:02<669::AID-IMMU669>3.0.CO;2-J

By:

Suri-Payer, Elisabeth;
Amar, Anna Z.;
McHugh, Rebecca;
Natarajan, Kannan;
Margulies, David H.;
Shevach, Ethan M.

Publication type:

Article

Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42255-w

By:

Meng, Yanxiang;
Garnish, Sarah E.;
Davies, Katherine A.;
Black, Katrina A.;
Leis, Andrew P.;
Horne, Christopher R.;
Hildebrand, Joanne M.;
Hoblos, Hanadi;
Fitzgibbon, Cheree;
Young, Samuel N.;
Dite, Toby;
Dagley, Laura F.;
Venkat, Aarya;
Kannan, Natarajan;
Koide, Akiko;
Koide, Shohei;
Glukhova, Alisa;
Czabotar, Peter E.;
Murphy, James M.

Publication type:

Article

Quantitative Structure–Mutation–Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction.

Published in:

BMC Bioinformatics, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12859-020-03842-6

By:

Huang, Liang-Chin;
Yeung, Wayland;
Wang, Ye;
Cheng, Huimin;
Venkat, Aarya;
Li, Sheng;
Ma, Ping;
Rasheed, Khaled;
Kannan, Natarajan

Publication type:

Article

LF4/MOK and a CDK-related kinase regulate the number and length of cilia in Tetrahymena.

Published in:

PLoS Genetics, 2019, v. 15, n. 7, p. 1, doi. 10.1371/journal.pgen.1008099

By:

Jiang, Yu-Yang;
Maier, Wolfgang;
Baumeister, Ralf;
Minevich, Gregory;
Joachimiak, Ewa;
Wloga, Dorota;
Ruan, Zheng;
Kannan, Natarajan;
Bocarro, Stephen;
Bahraini, Anoosh;
Vasudevan, Krishna Kumar;
Lechtreck, Karl;
Orias, Eduardo;
Gaertig, Jacek

Publication type:

Article

A Narrative Review of Herbal Medications in the Management of Mucositis in Head and Neck Cancer Patients.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2021, p. 143

By:

Kannan, Natarajan;
Asokan, Sharath;
Poddar, Sandeep;
Bhaumik, Amiya

Publication type:

Article

Randomized Controlled Trial for Comparative Assessment of Effect of Artificial Saliva Versus Virgin Coconut Oil on Salivary Proteolytic Activity & Radiation Mucositis in Patients undergoing Radiotherapy for Head and Neck Cancers.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2021, p. 52

By:

Kannan, Natarajan;
Asokan, Sharath;
Gopal, Keshav Ram;
Poddar, Sandeep;
Bhaumik, Amiya

Publication type:

Article

Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.859782

By:

Margulies, David H.;
Taylor, Daniel K.;
Jiang, Jiansheng;
Boyd, Lisa F.;
Ahmad, Javeed;
Mage, Michael G.;
Natarajan, Kannan

Publication type:

Article

Glanzmann Thrombasthenia Associated with Human Immunodeficiency Virus-positive Patient.

Published in:

International Journal of Preventive Medicine, 2014, v. 5, n. 4, p. 500

By:

Kumar Manne, Rakesh;
Natarajan, Kannan;
Patil, Rajendra;
Sarath Prathi, Venkata;
Sridevi Beeraka, Swapna;
Kumar Kolaparthi, Venkata Suneel

Publication type:

Article

Bayesian Survival Analysis With Nonproportional Hazards: Metanalysis of Combination Pravastatin-Aspirin.

Published in:

Journal of the American Statistical Association, 2004, v. 99, n. 465, p. 36, doi. 10.1198/016214504000000052

By:

Berry, Scott M.;
Berry, Donald A.;
Natarajan, Kannan;
Lin, Chen-Sheng;
Hennekens, Charles H.;
Belder, Rene

Publication type:

Article

Effect of Fermentation Parameters on Extra Cellular Tannase Production by Lactobacillus plantarum MTCC 1407.

Published in:

E-Journal of Chemistry, 2009, v. 6, n. 4, p. 979, doi. 10.1155/2009/505087

By:

Natarajan, Kannan;
Rajendran, Aravindan

Publication type:

Article

CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2.

Published in:

EMBO Journal, 2024, v. 43, n. 22, p. 5381, doi. 10.1038/s44318-024-00240-z

By:

Holder, James;
Miles, Jennifer A;
Batchelor, Matthew;
Popple, Harrison;
Walko, Martin;
Yeung, Wayland;
Kannan, Natarajan;
Wilson, Andrew J;
Bayliss, Richard;
Gergely, Fanni

Publication type:

Article

Identification and classification of small molecule kinases: insights into substrate recognition and specificity.

Published in:

BMC Evolutionary Biology, 2016, v. 16, p. 1, doi. 10.1186/s12862-015-0576-x

By:

Oruganty, Krishnadev;
Talevich, Eric E.;
Neuwald, Andrew F.;
Kannan, Natarajan

Publication type:

Article

Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factors.

Published in:

BMC Evolutionary Biology, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2148-13-117

By:

Talevich, Eric;
Kannan, Natarajan

Publication type:

Article

Cataloguing the dead: breathing new life into pseudokinase research.

Published in:

FEBS Journal, 2020, v. 287, n. 19, p. 4150, doi. 10.1111/febs.15246

By:

Shrestha, Safal;
Byrne, Dominic P.;
Harris, John A.;
Kannan, Natarajan;
Eyers, Patrick A.

Publication type:

Article

Prediction and Prioritization of Rare Oncogenic Mutations in the Cancer Kinome Using Novel Features and Multiple Classifiers.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.pcbi.1003545

By:

U, ManChon;
Talevich, Eric;
Katiyar, Samiksha;
Rasheed, Khaled;
Kannan, Natarajan

Publication type:

Article

A study on novel coupled membrane bioreactor with electro oxidation for biofouling reduction.

Published in:

Environmental Engineering Research, 2021, v. 26, n. 4, p. 1, doi. 10.4491/eer.2020.039

By:

Vasanthapalaniappan, Kamalakannan;
Palani, Kavitha;
Saravanabhavan, Shanmuga Sundar;
Jonna, Narendranath;
Pounsamy, Maharaja;
Natarajan, Kannan;
Yun Suk Huh;
Natesan, Balasubramanian

Publication type:

Article

Emerging roles of the αC‐β4 loop in protein kinase structure, function, evolution, and disease.

Published in:

IUBMB Life, 2020, v. 72, n. 6, p. 1189, doi. 10.1002/iub.2253

By:

Yeung, Wayland;
Ruan, Zheng;
Kannan, Natarajan

Publication type:

Article

How the Virus Outsmarts the Host: Function and Structure of Cytomegalovirus MHC-I-Like Molecules in the Evasion of Natural Killer Cell Surveillance.

Published in:

Journal of Biomedicine & Biotechnology, 2011, p. 1, doi. 10.1155/2011/724607

By:

Revilleza, Maria Jamela;
Rui Wang;
Mans, Janet;
Manqing Hong;
Natarajan, Kannan;
Margulies, David H.

Publication type:

Article

Evolution of Functional Diversity in the Holozoan Tyrosine Kinome.

Published in:

Molecular Biology & Evolution, 2021, v. 38, n. 12, p. 5625, doi. 10.1093/molbev/msab272

By:

Yeung, Wayland;
Kwon, Annie;
Taujale, Rahil;
Bunn, Claire;
Venkat, Aarya;
Kannan, Natarajan

Publication type:

Article

Effective Adsorptive Removal of Coomassie Violet Dye from Aqueous Solutions Using Green Synthesized Zinc Hydroxide Nanoparticles Prepared from Calotropis gigantea Leaf Extract.

Published in:

ChemEngineering, 2023, v. 7, n. 2, p. 31, doi. 10.3390/chemengineering7020031

By:

Parimelazhagan, Vairavel;
Natarajan, Kannan;
Shanbhag, Srinath;
Madivada, Sumanth;
Kumar, Harish S.

Publication type:

Article

Hierarchical bayes quality measurement plan.

Published in:

Communications in Statistics: Simulation & Computation, 1998, v. 27, n. 1, p. 199, doi. 10.1080/03610919808813475

By:

Natarajan, Kannan;
Ghosh, Malay;
Maiti, Tapabrata

Publication type:

Article

The Hippo Pathway Maintains the Equatorial Division Plane in the Ciliate Tetrahymena.

Published in:

Genetics, 2017, v. 206, n. 2, p. 873, doi. 10.1534/genetics.117.200766

By:

Yu-Yang Jiang;
Maier, Wolfgang;
Baumeister, Ralf;
Minevich, Gregory;
Joachimiak, Ewa;
Zheng Ruan;
Kannan, Natarajan;
Clarke, Diamond;
Frankel, Joseph;
Gaertig, Jacek

Publication type:

Article

Effect of Humidity on Condensation in Vapour Compression Refrigeration System for Fresh Food Transport Vehicles.

Published in:

International Journal of Vehicle Structures & Systems (IJVSS), 2018, v. 10, n. 4, p. 296, doi. 10.4273/ijvss.10.4.14

By:

Sendrayaperumal, Nagarajan;
Rathinavel, Ganesh;
Vijayarangan, Arunagirinathan;
Natarajan, Kannan

Publication type:

Article

KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases.

Published in:

BMC Bioinformatics, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12859-021-04358-3

By:

Huang, Liang-Chin;
Taujale, Rahil;
Gravel, Nathan;
Venkat, Aarya;
Yeung, Wayland;
Byrne, Dominic P.;
Eyers, Patrick A.;
Kannan, Natarajan

Publication type:

Article

Kinase Regulation by Hydrophobic Spine Assembly in Cancer.

Published in:

Molecular & Cellular Biology, 2015, v. 35, n. 1, p. 264, doi. 10.1128/MCB.00943-14

By:

Jiancheng Hu;
Ahuja, Lalima G.;
Meharena, Hiruy S.;
Kannan, Natarajan;
Kornev, Alexandr P.;
Taylor, Susan S.;
Shaw, Andrey S.

Publication type:

Article

ProKinO: A Unified Resource for Mining the Cancer Kinome.

Published in:

Human Mutation, 2015, v. 36, n. 2, p. 175, doi. 10.1002/humu.22726

By:

McSkimming, Daniel Ian;
Dastgheib, Shima;
Talevich, Eric;
Narayanan, Anish;
Katiyar, Samiksha;
Taylor, Susan S.;
Kochut, Krys;
Kannan, Natarajan

Publication type:

Article

Cancer-associated mutations in protein kinase C theta are loss-of-function.

Published in:

Biochemical Journal, 2024, v. 481, n. 12, p. 759, doi. 10.1042/bcj20240148

By:

Hodapp, Stefanie J.;
Gravel, Nathan;
Kannan, Natarajan;
Newton, Alexandra C.

Publication type:

Article

Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2.

Published in:

Biochemical Journal, 2023, v. 480, n. 2, p. 141, doi. 10.1042/BCJ20220474

By:

Byrne, Dominic P.;
Shrestha, Safal;
Daly, Leonard A.;
Marensi, Vanessa;
Ramakrishnan, Krithika;
Eyers, Claire E.;
Kannan, Natarajan;
Eyers, Patrick A.

Publication type:

Article

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner.

Published in:

Biochemical Journal, 2015, v. 467, n. 1, p. 47, doi. 10.1042/BJ20141441

By:

Bailey, Fiona P.;
Byrne, Dominic P.;
Oruganty, Krishnadev;
Eyers, Claire E.;
Novotny, Christopher J.;
Shokat, Kevan M.;
Kannan, Natarajan;
Eyers, Patrick A.

Publication type:

Article

Going for broke: targeting the human cancer pseudokinome.

Published in:

Biochemical Journal, 2015, v. 465, n. 2, p. 195, doi. 10.1042/BJ20141060

By:

Bailey, Fiona P.;
Byrne, Dominic P.;
McSkimming, Daniel;
Kannan, Natarajan;
Eyers, Patrick A.

Publication type:

Article

A dynamic sweat transfer tester for analyzing transverse sweat transfer properties of multi-weave structure fabrics.

Published in:

Journal of Industrial Textiles, 2014, v. 44, n. 2, p. 211, doi. 10.1177/1528083713481836

By:

Raja, Dhanakodi;
Babu, Venugopal Ramesh;
Senthilkumar, Mani;
Ramakrishnan, Govindan;
Kannan, Natarajan

Publication type:

Article

Clinical and radiological assessment of effects of long-term corticosteroid therapy on oral health.

Published in:

Dental Research Journal, 2013, v. 10, n. 5, p. 666

By:

Beeraka, Swapna Sridevi;
Natarajan, Kannan;
Patil, Rajendra;
Manne, Rakesh Kumar;
Prathi, Venkata Sarath;
Kolaparthi, Venkata Suneel Kumar

Publication type:

Article

Modeling and optimization of tannase production with Triphala in packed bed reactor by response surface methodology, genetic algorithm, and artificial neural network.

Published in:

3 Biotech, 2019, v. 9, n. 7, p. N.PAG, doi. 10.1007/s13205-019-1763-z

By:

Selvaraj, Subbalaxmi;
Vytla, Ramachandra Murty;
Vijay, G. S.;
Natarajan, Kannan

Publication type:

Article

A comprehensive in vivo screen of yeast farnesyltransferase activity reveals broad reactivity across a majority of CXXX sequences.

Published in:

G3: Genes | Genomes | Genetics, 2023, v. 13, n. 7, p. 1, doi. 10.1093/g3journal/jkad094

By:

Kim, June H.;
Hildebrandt, Emily R.;
Sarkar, Anushka;
Yeung, Wayland;
Waldon, La Ryel A.;
Kannan, Natarajan;
Schmidt, Walter K.

Publication type:

Article

Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition.

Published in:

Science Signaling, 2022, v. 15, n. 753, p. 1, doi. 10.1126/scisignal.abk1147

By:

Pilo, Caila A.;
Baffi, Timothy R.;
Kornev, Alexandr P.;
Kunkel, Maya T.;
Malfavon, Mario;
Chen, Dong-Hui;
Rossitto, Leigh-Ana;
Chen, Daniel X.;
Huang, Liang-Chin;
Longman, Cheryl;
Kannan, Natarajan;
Raskind, Wendy H.;
Gonzalez, David J.;
Taylor, Susan S.;
Gorrie, George;
Newton, Alexandra C.

Publication type:

Article

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.

Published in:

Science Signaling, 2021, v. 14, n. 678, p. 1, doi. 10.1126/scisignal.abe4509

By:

Baffi, Timothy R.;
Lordén, Gema;
Wozniak, Jacob M.;
Feichtner, Andreas;
Yeung, Wayland;
Kornev, Alexandr P.;
King, Charles C.;
Del Rio, Jason C.;
Limaye, Ameya J.;
Bogomolovas, Julius;
Gould, Christine M.;
Chen, Ju;
Kennedy, Eileen J.;
Kannan, Natarajan;
Gonzalez, David J.;
Stefan, Eduard;
Taylor, Susan S.;
Newton, Alexandra C.

Publication type:

Article

A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily.

Published in:

Science Signaling, 2020, v. 13, n. 639, p. 1, doi. 10.1126/scisignal.aax6313

By:

Shrestha, Safal;
Katiyar, Samiksha;
Sanz-Rodriguez, Carlos E.;
Kemppinen, Nolan R.;
Kim, Hyun W.;
Kadirvelraj, Renuka;
Panagos, Charalampos;
Keyhaninejad, Neda;
Colonna, Maxwell;
Chopra, Pradeep;
Byrne, Dominic P.;
Boons, Geert J.;
van der Knaap, Esther;
Eyers, Patrick A.;
Edison, Arthur S.;
Wood, Zachary A.;
Kannan, Natarajan

Publication type:

Article

Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity.

Published in:

Science Signaling, 2020, v. 13, n. 639, p. 1, doi. 10.1126/scisignal.aax2713

By:

Byrne, Dominic P.;
Shrestha, Safal;
Galler, Martin;
Cao, Min;
Daly, Leonard A.;
Campbell, Amy E.;
Eyers, Claire E.;
Veal, Elizabeth A.;
Kannan, Natarajan;
Eyers, Patrick A.

Publication type:

Article

MICROBIAL PRODUCTION OF SILVER NANOPARTICLES.

Published in:

Digest Journal of Nanomaterials & Biostructures (DJNB), 2010, v. 5, n. 1, p. 135

By:

Natarajan, Kannan;
Selvaraj, Subbalaxmi;
Murty, V. Ramachandra

Publication type:

Article

Functional classification and validation of yeast prenylation motifs using machine learning and genetic reporters.

Published in:

PLoS ONE, 2022, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0270128

By:

Berger, Brittany M.;
Yeung, Wayland;
Goyal, Arnav;
Zhou, Zhongliang;
Hildebrandt, Emily R.;
Kannan, Natarajan;
Schmidt, Walter K.

Publication type:

Article

Perspectives on Virtual (Remote) Clinical Trials as the "New Normal" to Accelerate Drug Development.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 2, p. 373, doi. 10.1002/cpt.2248

By:

Alemayehu, Demissie;
Hemmings, Robert;
Natarajan, Kannan;
Roychoudhury, Satrajit

Publication type:

Article

Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand.

Published in:

Nature, 1999, v. 402, n. 6762, p. 623, doi. 10.1038/45170

By:

Tormo, Jose;
Natarajan, Kannan

Publication type:

Article