Title: Removing "flavor" from pathogenic antibodies hits a therapeutic sweet spot.
Authors: Vergoossen, Dana L. E.; Huijbers, Maartje G.
Abstract: Endoglycosidase CU43 removes IgG Fc glycans, inhibits IgG effector functions, and prevents pathology in multiple disease models.
Subjects: IMMUNE response; PATHOLOGY; GLYCANS; IMMUNOGLOBULINS; FLAVOR
Publication: Science Immunology, 2024, Vol 9, Issue 102, pN.PAG
ISSN: 2470-9468
Publication type: Academic Journal
DOI: 10.1126/sciimmunol.adu8805

Removing "flavor" from pathogenic antibodies hits a therapeutic sweet spot.

Vergoossen, Dana L. E.; Huijbers, Maartje G.