Works matching DE "T-cell exhaustion"
Results: 680
Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming.
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- PLoS Biology, 2024, v. 22, n. 12, p. 1, doi. 10.1371/journal.pbio.3002943
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Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment.
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- NPJ Aging, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41514-024-00138-4
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Architects of immunity: How dendritic cells shape CD8<sup>+</sup> T cell fate in cancer.
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- Science Immunology, 2025, v. 10, n. 103, p. 1, doi. 10.1126/sciimmunol.adf4726
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Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression.
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- Science Immunology, 2025, v. 10, n. 103, p. 1, doi. 10.1126/sciimmunol.adn1945
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The redox sensor KEAP1 facilitates adaptation of T cells to chronic antigen stimulation by preventing hyperactivation.
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- Science Immunology, 2024, v. 9, n. 101, p. 1, doi. 10.1126/sciimmunol.adk2954
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Intratumoral antigen signaling traps CD8<sup>+</sup> T cells to confine exhaustion to the tumor site.
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- Science Immunology, 2024, v. 9, n. 95, p. 1, doi. 10.1126/sciimmunol.ade2094
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TIM-3<sup>+</sup> CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies.
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- Science Immunology, 2024, v. 9, n. 94, p. 1, doi. 10.1126/sciimmunol.adg1094
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Beyond T cell exhaustion: TIM-3 regulation of myeloid cells.
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- Science Immunology, 2024, v. 9, n. 93, p. 1, doi. 10.1126/sciimmunol.adf2223
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SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19.
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- Science Immunology, 2023, v. 8, n. 90, p. 1, doi. 10.1126/sciimmunol.adh0687
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Selective control of transposable element expression during T cell exhaustion and anti–PD-1 treatment.
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- Science Immunology, 2023, v. 8, n. 88, p. 1, doi. 10.1126/sciimmunol.adf8838
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ESMO news – May 2024.
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- Oncolog-Hematolog, 2024, n. 67, p. 5
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Impact of HIV-Related Immune Impairment of Yellow Fever Vaccine Immunogenicity in People Living with HIV—ANRS 12403.
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- Vaccines, 2024, v. 12, n. 6, p. 578, doi. 10.3390/vaccines12060578
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Intranodal Injection of Immune Activator Demonstrates Antitumor Efficacy in an Adjuvant Approach.
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- Vaccines, 2024, v. 12, n. 4, p. 355, doi. 10.3390/vaccines12040355
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Sustained Liver HBsAg Loss and Clonal T- and B-Cell Expansion upon Therapeutic DNA Vaccination Require Low HBsAg Levels.
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- Vaccines, 2023, v. 11, n. 12, p. 1825, doi. 10.3390/vaccines11121825
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Therapeutic Cancer Vaccines and Their Future Implications.
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- Vaccines, 2023, v. 11, n. 3, p. 660, doi. 10.3390/vaccines11030660
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Enhancement of Vaccine-Induced T-Cell Responses by PD-L1 Blockade in Calves.
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- Vaccines, 2023, v. 11, n. 3, p. 559, doi. 10.3390/vaccines11030559
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Ex Vivo Blockade of the PD-1 Pathway Improves Recall IFNγ Responses of HIV-Infected Persons on Antiretroviral Therapy.
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- Vaccines, 2023, v. 11, n. 2, p. 211, doi. 10.3390/vaccines11020211
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Updated Insights into the T Cell-Mediated Immune Response against SARS-CoV-2: A Step towards Efficient and Reliable Vaccines.
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- Vaccines, 2023, v. 11, n. 1, p. 101, doi. 10.3390/vaccines11010101
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CD39 的临床意义及其与肝癌浸润 T 细胞耗竭的相关性分析.
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- Progress in Modern Biomedicine, 2023, v. 23, n. 10, p. 1815, doi. 10.13241/j.cnki.pmb.2023.10.003
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T Cell Exhaustion and CAR-T Immunotherapy in Hematological Malignancies.
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- BioMed Research International, 2021, p. 1, doi. 10.1155/2021/6616391
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Chimera and Tandem-Repeat Type Galectins: The New Targets for Cancer Immunotherapy.
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- Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 902, doi. 10.3390/biom13060902
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New pathogen for gastric cancer: Streptococcus anginosus.
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- Clinical & Translational Medicine, 2024, v. 14, n. 12, p. 1, doi. 10.1002/ctm2.70104
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Single‐cell transcriptome analysis deciphers the CD74‐mediated immune evasion and tumour growth in lung squamous cell carcinoma with chronic obstructive pulmonary disease.
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- Clinical & Translational Medicine, 2024, v. 14, n. 8, p. 1, doi. 10.1002/ctm2.1786
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Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor.
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- Clinical & Translational Medicine, 2024, v. 14, n. 6, p. 1, doi. 10.1002/ctm2.1691
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PI3K/mTOR inhibition induces tumour microenvironment remodelling and sensitises pS6<sup>high</sup> uterine leiomyosarcoma to PD‐1 blockade.
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- Clinical & Translational Medicine, 2024, v. 14, n. 5, p. 1, doi. 10.1002/ctm2.1655
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Distinct fibroblast subpopulations associated with bone, brain or intrapulmonary metastasis in advanced non‐small‐cell lung cancer.
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- Clinical & Translational Medicine, 2024, v. 14, n. 3, p. 1, doi. 10.1002/ctm2.1605
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Single‐cell profiling reveals tumour cell heterogeneity accompanying a pre‐malignant and immunosuppressive microenvironment in gastric adenocarcinoma.
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- Clinical & Translational Medicine, 2023, v. 13, n. 12, p. 1, doi. 10.1002/ctm2.1490
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Deep phenotyping of the lipidomic response in COVID‐19 and non‐COVID‐19 sepsis.
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- Clinical & Translational Medicine, 2023, v. 13, n. 11, p. 1, doi. 10.1002/ctm2.1440
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LILRB3 suppresses immunity in glioma and is associated with poor prognosis.
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- Clinical & Translational Medicine, 2023, v. 13, n. 10, p. 1, doi. 10.1002/ctm2.1396
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Single‐cell transcriptomics identify TNFRSF1B as a novel T‐cell exhaustion marker for ovarian cancer.
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- Clinical & Translational Medicine, 2023, v. 13, n. 9, p. 1, doi. 10.1002/ctm2.1416
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The Y of cancer sex differences.
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- Clinical & Translational Medicine, 2023, v. 13, n. 9, p. 1, doi. 10.1002/ctm2.1402
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Expression analysis of genes important for maintaining skin function in a senescence‐accelerated mouse prone model.
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- Geriatrics & Gerontology International, 2023, v. 23, n. 12, p. 951, doi. 10.1111/ggi.14718
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Modern cancer therapy: cryoablation meets immune checkpoint blockade.
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- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1323070
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A transcriptional evaluation of the melanoma and squamous cell carcinoma TIL compartment reveals an unexpected spectrum of exhausted and functional T cells.
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- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1200387
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Identification and validation of PCSK9 as a prognostic and immune-related influencing factor in tumorigenesis: a pan-cancer analysis.
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- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1134063
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Identification of immunosuppressive signature subtypes and prognostic risk signatures in triple-negative breast cancer.
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- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1108472
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Construction of T cell exhaustion model for predicting survival and immunotherapy effect of bladder cancer based on WGCNA.
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- Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1196802
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Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment.
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- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1171926
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Patients with advanced pancreatic and biliary cancer appear vulnerable to SARS-CoV-2 Omicron variant: An observational study during the COVID-19 outbreak in Shanghai.
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- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1115293
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Low expression of HIF1AN accompanied by less immune infiltration is associated with poor prognosis in breast cancer.
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- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1080910
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Identification of IRF-associated molecular subtypes in clear cell renal cell carcinoma to characterize immunological characteristics and guide therapy.
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- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2022.1118472
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CD26<sup>low</sup>PD-1<sup>+</sup> CD8 T cells are terminally exhausted and associated with leukemia progression in acute myeloid leukemia.
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- Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1169144
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Strategies to reinvigorate exhausted CD8<sup>+</sup> T cells in tumor microenvironment.
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- Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1204363
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Hierarchical transcriptional network governing heterogeneous T cell exhaustion and its implications for immune checkpoint blockade.
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- Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1198551
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PD-1<sup>Hi</sup> CAR-T cells provide superior protection against solid tumors.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1187850
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CD38 marks the exhausted CD8<sup>+</sup> tissue-resident memory T cells in hepatocellular carcinoma.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1182016
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Monitoring immunomodulation strategies in type 1 diabetes.
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- Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1206874
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IL-27-containing exosomes secreted by innate B-1a cells suppress and ameliorate uveitis.
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- Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1071162
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Integrating machine learning and single-cell trajectories to analyze T-cell exhaustion to predict prognosis and immunotherapy in colon cancer patients .
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1162843
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Demethylating therapy increases cytotoxicity of CD44v6 CAR-T cells against acute myeloid leukemia.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1145441
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