Works matching DE "COMPLEMENT activation"

Results: 1801

The Immune System.

Published in:

Current Allergy & Clinical Immunology, 2025, v. 38, n. 2, p. 116

By:

Emanuel, Shaunagh;
Hawarden, Di

Publication type:

Article

Human Fcγ-receptors selectively respond to C-reactive protein isoforms.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1598605

By:

Henning, Anna;
Seer, Johanna;
Zeller, Johannes;
Peter, Karlheinz;
Chen, Haizhang;
Thomé, Julia;
Kolb, Philipp;
Eisenhardt, Steffen U.;
Hoffmann, Katja;
Hengel, Hartmut

Publication type:

Article

A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibitor, in patients with mild to moderate atopic dermatitis: a proof-of-concept study with Post-hoc biomarker analysis

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1560447

By:

Baek, Gyeong Ho;
Kim, Bo Ri;
Shin, Jung-Won;
Huh, Chang Hun;
Hwang, Jungjoong;
Ko, Sungmin;
Kim, Siwon;
Ho, Pil-Su;
Kim, Kyu-Han;
Park, Chun Wook;
Seo, Seong Jun;
Park, Chang-Ook;
Shin, Dongyoon;
Kim, Yeongshin;
Kim, Youngsoo;
Seong, Seung-Yong;
Na, Jung-Im

Publication type:

Article

A homogeneous immunoassay technology based on liposomes and the complement system enables one-step, no-wash, rapid diagnostics directly in serum.

Published in:

Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 15, p. 3257, doi. 10.1007/s00216-025-05882-4

By:

Hoecherl, Kilian;
Streif, Simon;
Spitzenberg, Clemens;
Rink, Simone;
Behrent, Arne;
Holzhausen, Ferdinand;
Griesche, Christian;
Rogoll, Cornelia;
Foedlmeier, Maximilian;
Gebhard, Anna;
Kulikowski, Kacper;
Schaefer, Nicole;
Pauly, Diana;
Baeumner, Antje J.

Publication type:

Article

Current Understanding of the Pathogenesis of ANCA-Associated Vasculitis and Novel Treatment Options Targeting Complement Activation.

Published in:

Life (2075-1729), 2025, v. 15, n. 5, p. 756, doi. 10.3390/life15050756

By:

Drouzas, Konstantinos;
Kalogeropoulos, Petros;
Liapis, George;
Lionaki, Sophia

Publication type:

Article

The Role of Complement in the Pathogenesis and Treatment of Myasthenia Gravis.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 739, doi. 10.3390/cells14100739

By:

Martinez Salazar, Armando;
Mokhtari, Sepideh;
Peguero, Edwin;
Jaffer, Muhammad

Publication type:

Article

Perspective on Renal Involvement in Antiphospholipid Syndrome: Implications for Diagnosis, Pathogenesis, and Treatment.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 10, p. 3326, doi. 10.3390/jcm14103326

By:

Hoxha, Ariela;
Del Prete, Dorella;
Condonato, Irene;
Martino, Francesca K.;
Lovisotto, Marco;
Nalesso, Federico;
Simioni, Paolo

Publication type:

Article

Th2 predominance and decreased NK cells in patients with hereditary angioedema.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1536128

By:

Sundler Björkman, Linda;
Elmér, Evelina;
Egesten, Arne;
Skattum, Lillemor

Publication type:

Article

HTRA1 and complement activation in neovascular age-related macular degeneration.

Published in:

Japanese Journal of Ophthalmology, 2025, v. 69, n. 3, p. 453, doi. 10.1007/s10384-024-01153-4

By:

Tanaka, Keiichiro;
Omori, Tomoko;
Oguchi, Yasuharu;
Itagaki, Kanako;
Kato, Yutaka;
Honjo, Junichiro;
Norikawa, Koki;
Sugano, Yukinori;
Mukai, Ryo;
Ishida, Yumi;
Machida, Takeshi;
Sekine, Hideharu;
Sekiryu, Tetsuju

Publication type:

Article

Pannexin-1: the missing link?

Published in:

Nature Reviews Microbiology, 2007, v. 5, n. 6, p. 398, doi. 10.1038/nrmicro1682

By:

Ahmad, Sharon

Publication type:

Article

In Brief.

Published in:: Nature Reviews Microbiology, 2006, v. 4, n. 7, p. 491, doi. 10.1038/nrmicro1459
Publication type:: Article

Identification of c-Jun phosphorylation as a crucial mediator of complement activation in renal ischemia-reperfusion injury revealed by phosphoproteomics and functional validation.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10414-5

By:

Zhao, Yufeng;
Cao, Yirui;
Su, Ying;
Chen, Juntao;
Wang, Xuanchuan;
Ding, Peipei;
Hu, Weiguo;
Zhu, Tongyu;
Hu, Chao

Publication type:

Article

Microglia-mediated neuroinflammation in traumatic brain injury: a review.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09995-4

By:

Obukohwo, Oyovwi Mega;
Oreoluwa, Oyelere Abosede;
Andrew, Udi Onoriode;
Williams, Ugwuishi Emeka

Publication type:

Article

A Vanka‐based parameter‐robust multigrid relaxation for the Stokes–Darcy Brinkman problems.

Published in:

Numerical Linear Algebra with Applications, 2023, v. 30, n. 6, p. 1, doi. 10.1002/nla.2514

By:

He, Yunhui

Publication type:

Article

Molecular profiling and therapeutic tailoring to address disease heterogeneity in systemic lupus erythematosus.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01484-z

By:

Karmakar, Abhibroto;
Kumar, Uma;
Prabhu, Smitha;
Ravindran, Vinod;
Nagaraju, Shankar Prasad;
Suryakanth, Varashree Bolar;
Prabhu, Mukhyaprana M.;
Karmakar, Subhradip

Publication type:

Article

A Microfluidics‐Based Screening Tool to Assess the Impact of Blood Plasma Factors on Microvascular Integrity.

Published in:

Advanced Biology, 2021, v. 5, n. 11, p. 1, doi. 10.1002/adbi.202100954

By:

Junaid, Abidemi;
van Duinen, Vincent;
Stam, Wendy;
Dólleman, Sophie;
Yang, Wei;
de Rijke, Yolanda;
Endeman, Hendrik;
van Kooten, Cees;
Mashaghi, Alireza;
de Boer, Hetty;
van Gils, Janine;
Hankemeier, Thomas;
van Zonneveld, Anton Jan

Publication type:

Article

Edwardsiella tarda TraT is an anti-complement factor and a cellular infection promoter.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03587-3

By:

Li, Mofei;
Wu, Meng;
Sun, Yuanyuan;
Sun, Li

Publication type:

Article

Neuronal–glial communication perturbations in murine SOD1<sup>G93A</sup> spinal cord.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03128-y

By:

MacLean, Michael;
López-Díez, Raquel;
Vasquez, Carolina;
Gugger, Paul F.;
Schmidt, Ann Marie

Publication type:

Article

T-cell regulation: with complements from innate immunity.

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 1, p. 9, doi. 10.1038/nri1994

By:

Kemper, Claudia;
Atkinson, John P.

Publication type:

Article

The movement of activation.

Published in:

Nature Reviews Immunology, 2006, v. 6, n. 12, p. 882, doi. 10.1038/nri1981

By:

Leavy, Olive

Publication type:

Article

Optimization of a Plasma Rich in Growth Factors Membrane for the Treatment of Inflammatory Ocular Diseases.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 10, p. N.PAG, doi. 10.3390/bioengineering9100508

By:

Anitua, Eduardo;
Fuente, María de la;
Merayo-Lloves, Jesús;
Muruzabal, Francisco

Publication type:

Article

Liposome-Mediated Triggering of Complement Cascade.

Published in:

Journal of Liposome Research, 2008, v. 18, n. 3, p. 195, doi. 10.1080/08982100802309552

By:

Moghimi, S. Moein;
Hamad, Islam

Publication type:

Article

Physicochemical Characterization and Study of in vitro Interactions of pH-sensitive Liposomes with the Complement System.

Published in:

Journal of Liposome Research, 2008, v. 18, n. 1, p. 59, doi. 10.1080/08982100801893986

By:

Carmo, Vildete A. S.;
De Oliveira, Mônica C.;
Reis, Eduardo C. O.;
Guimarães, Tânia M. P. D.;
Vilela, José M. C.;
Andrade, Margareth S.;
Michalick, Marilene S. M.;
Cardoso, Valbert N.

Publication type:

Article

ROLE OF COMPLEMENT ACTIVATION IN HYPERSENSITIVITY REACTIONS TO DOXIL AND HYNIC PEG LIPOSOMES: EXPERIMENTAL AND CLINICAL STUDIES.

Published in:

Journal of Liposome Research, 2002, v. 12, n. 1/2, p. 165, doi. 10.1081/LPR-120004790

By:

Szebeni, J.;
Baranyi, L.;
Savay, S.;
Milosevits, J.;
Bunger, R.;
Laverman, P.;
Metselaar, J. M.;
Storm, G.;
Chanan-Khan, A.;
Liebes, L.;
Muggia, F. M.;
Cohen, R.;
Barenholz, Y.;
Alving, C. R.

Publication type:

Article

Evaluation of the effects of herpes simplex glycoprotein B on complement system and cytokines in in vitro models of Alzheimer's disease.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 9, p. 1368, doi. 10.1002/jat.4471

By:

Yirün, Anil;
Çakır, Deniz Arca;
Sanajou, Sonia;
Erdemli Köse, Selinay Başak;
Özyurt, Aylin Balcı;
Zeybek, Dilara;
Bozdemir, Özlem;
Baydar, Terken;
Erkekoglu, Pinar

Publication type:

Article

Binding is not enough; autoantibodies do more to garner complements.

Published in:

Science Immunology, 2019, v. 4, n. 37, p. 1, doi. 10.1126/sciimmunol.aax9510

By:

Ruff, William E.;
O'Connor, Kevin C.

Publication type:

Article

The Extended Use of Eculizumab in Pregnancy and Complement Activation–Associated Diseases Affecting Maternal, Fetal and Neonatal Kidneys—The Future Is Now?

Published in:

Journal of Clinical Medicine, 2019, p. 407, doi. 10.3390/jcm8030407

By:

Stefanovic, Vedran

Publication type:

Article

Epigenetics and treatment of systemic lupus erythematosus.

Published in:

Pharmacia (0428-0296), 2023, v. 70, n. 4, p. 1005, doi. 10.3897/pharmacia.70.e110412

By:

Behluli, Emir;
Liehr, Thomas;
Hadziselimovic, Rifat;
Temaj, Gazmend

Publication type:

Article

Effect of platelet storage on complement activation.

Published in:

Egyptian Journal of Haematology, 2023, v. 48, n. 1, p. 66, doi. 10.4103/ejh.ejh_53_21

By:

Mahmoud, Amal A.;
Mohamed, Maha A.;
Ahmed, Shimaa A.;
Abdallah, Mariam E.

Publication type:

Article

Mechanisms of resistance to daratumumab in patients with multiple myeloma.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 135, n. 4, p. 401, doi. 10.1111/bcpt.14054

By:

Iversen, Katrine Fladeland

Publication type:

Article

First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2022, v. 131, n. 2, p. 114, doi. 10.1111/bcpt.13756

By:

Ort, Marion;
Dingemanse, Jasper;
Hsin, Chih‐hsuan;
Richard, Muriel;
Huehn, Eva;
Sabattini, Giancarlo;
van de Wetering, Jeroen;
Kornberger, Rüdiger;
van den Anker, John;
Kaufmann, Priska

Publication type:

Article

Clinicoserological insights into patients with immune checkpoint inhibitor‐induced myasthenia gravis.

Published in:

Annals of Clinical & Translational Neurology, 2023, v. 10, n. 5, p. 825, doi. 10.1002/acn3.51761

By:

Masi, Gianvito;
Pham, Minh C.;
Karatz, Tabitha;
Oh, Sangwook;
Payne, Aimee S.;
Nowak, Richard J.;
Howard, James F.;
Guptill, Jeffrey T.;
Juel, Vern C.;
O'Connor, Kevin C.

Publication type:

Article

Impact of complement activation on clinical outcomes in multiple sclerosis.

Published in:

Annals of Clinical & Translational Neurology, 2021, v. 8, n. 4, p. 944, doi. 10.1002/acn3.51334

By:

Keller, Christian W.;
Oechtering, Johanna;
Wiendl, Heinz;
Kappos, Ludwig;
Kuhle, Jens;
Lünemann, Jan D.

Publication type:

Article

Terminal complement activation is increased and associated with disease severity in CIDP.

Published in:

Annals of Clinical & Translational Neurology, 2016, v. 3, n. 9, p. 730, doi. 10.1002/acn3.331

By:

Quast, Isaak;
Keller, Christian W.;
Hiepe, Falk;
Tackenberg, Björn;
Lünemann, Jan D.

Publication type:

Article

Neuroprotective effects of intravenous immunoglobulin are mediated through inhibition of complement activation and apoptosis in a rat model of sepsis.

Published in:

Intensive Care Medicine Experimental, 2017, v. 5, n. 1, p. 1, doi. 10.1186/s40635-016-0114-1

By:

Esen, Figen;
Orhun, Gunseli;
Ozcan, Perihan;
Senturk, Evren;
Kucukerden, Melike;
Giris, Murat;
Akcan, Ugur;
Orhan, Nurcan;
Tuzun, Erdem;
Yilmaz, Canan;
Kaya, Mehmet;
Arican, Nadir;
Gazioglu, Sema

Publication type:

Article

The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation.

Published in:

Clinical & Translational Immunology, 2023, v. 12, n. 1, p. 1, doi. 10.1002/cti2.1436

By:

de Boer, Esther CW;
Thielen, Astrid JF;
Langereis, Jeroen D;
Kamp, Angela;
Brouwer, Mieke C;
Oskam, Nienke;
Jongsma, Marlieke L;
Baral, April J;
Spaapen, Robbert M;
Zeerleder, Sacha;
Vidarsson, Gestur;
Rispens, Theo;
Wouters, Diana;
Pouw, Richard B;
Jongerius, Ilse

Publication type:

Article

SARS‐CoV‐2 triggers complement activation through interactions with heparan sulfate.

Published in:

Clinical & Translational Immunology, 2022, v. 11, n. 8, p. 1, doi. 10.1002/cti2.1413

By:

Lo, Martin W;
Amarilla, Alberto A;
Lee, John D;
Albornoz, Eduardo A;
Modhiran, Naphak;
Clark, Richard J;
Ferro, Vito;
Chhabra, Mohit;
Khromykh, Alexander A;
Watterson, Daniel;
Woodruff, Trent M

Publication type:

Article

Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killing.

Published in:

Clinical & Translational Immunology, 2021, v. 10, n. 4, p. 1, doi. 10.1002/cti2.1256

By:

Langereis, Jeroen D;
Molen, Renate G;
Kat Angelino, Corrie;
Henriet, Stefanie S;
Jonge, Marien I;
Joosten, Irma;
Simons, Annet;
Schuurs‐Hoeijmakers, Janneke HM;
Deuren, Marcel;
Aerde, Koen;
Flier, Michiel

Publication type:

Article

Role of uromodulin and complement activation in the progression of kidney disease.

Published in:

Oncology Letters, 2021, v. 22, n. 6, p. N.PAG, doi. 10.3892/ol.2021.13090

By:

Shen, Fei;
Liu, Maojing;
Pei, Fei;
Yu, Li;
Yang, Xiangdong

Publication type:

Article

Thrombotic risk in paroxysmal nocturnal hemoglobinuria-like (PNH-like) phenotype.

Published in:

Clinical Hemorheology & Microcirculation, 2021, v. 79, n. 4, p. 491, doi. 10.3233/CH-190735

By:

Carlisi, Melania;
Mancuso, Salvatrice;
Caimi, Gregorio;
Siragusa, Sergio

Publication type:

Article

Comprehensive investigation of in vitro hemocompatibility of surface modified polyamidoamine nanocarrier.

Published in:

Clinical Hemorheology & Microcirculation, 2020, v. 74, n. 3, p. 267, doi. 10.3233/CH-190641

By:

Li, Guanhua;
Zhang, Yu;
Tang, Wei;
Zheng, Junmeng

Publication type:

Article

Inherited defects in the complement system.

Published in:

Pediatric Allergy & Immunology, 2022, v. 33, p. 73, doi. 10.1111/pai.13635

By:

Leonardi, Lucia;
La Torre, Francesco;
Soresina, Annarosa;
Federici, Silvia;
Cancrini, Caterina;
Castagnoli, Riccardo;
Cinicola, Bianca Laura;
Corrente, Stefania;
Giardino, Giuliana;
Lougaris, Vassilios;
Volpi, Stefano;
Marseglia, Gian Luigi;
Cardinale, Fabio

Publication type:

Article

Inherited defects in the complement system.

Published in:

Pediatric Allergy & Immunology, 2022, v. 33, p. 73, doi. 10.1111/pai.13635

By:

Leonardi, Lucia;
La Torre, Francesco;
Soresina, Annarosa;
Federici, Silvia;
Cancrini, Caterina;
Castagnoli, Riccardo;
Cinicola, Bianca Laura;
Corrente, Stefania;
Giardino, Giuliana;
Lougaris, Vassilios;
Volpi, Stefano;
Marseglia, Gian Luigi;
Cardinale, Fabio

Publication type:

Article

Biological Activity and NMR-Fingerprinting of Balkan Endemic Species Stachys thracica Davidov.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 3, p. 251, doi. 10.3390/metabo12030251

By:

Mantovska, Desislava I.;
Zhiponova, Miroslava K.;
Georgiev, Milen I.;
Alipieva, Kalina;
Tsacheva, Ivanka;
Simova, Svetlana;
Yordanova, Zhenya P.

Publication type:

Article

A Histological Analysis and Detection of Complement Regulatory Protein CD55 in SARS-CoV-2 Infected Lungs.

Published in:

Life (2075-1729), 2024, v. 14, n. 9, p. 1058, doi. 10.3390/life14091058

By:

Silawal, Sandeep;
Gögele, Clemens;
Pelikan, Petr;
Werner, Christian;
Levidou, Georgia;
Mahato, Raman;
Schulze-Tanzil, Gundula

Publication type:

Article

Interaction Studies of Hexameric and Pentameric IgMs with Serum-Derived C1q and Recombinant C1q Mimetics.

Published in:

Life (2075-1729), 2024, v. 14, n. 5, p. 638, doi. 10.3390/life14050638

By:

John, Maria Magdalena;
Hunjadi, Monika;
Hawlin, Vanessa;
Reiser, Jean-Baptiste;
Kunert, Renate

Publication type:

Article

The Complement System: A Potential Therapeutic Target in Liver Cancer.

Published in:

Life (2075-1729), 2022, v. 12, n. 10, p. 1532, doi. 10.3390/life12101532

By:

Yuan, Meng;
Liu, Li;
Wang, Chenlin;
Zhang, Yan;
Zhang, Jiandong

Publication type:

Article

Immune-challenged house wren broods differ in the relative strengths of their responses among different axes of the immune system.

Published in:

Journal of Evolutionary Biology, 2008, v. 21, n. 3, p. 873, doi. 10.1111/j.1420-9101.2008.01503.x

By:

Forsman, A. M.;
Vogel, L. A.;
Sakaluk, S. K.;
Grindstaff, J. L.;
Thompson, C. F.

Publication type:

Article

The "C3aR Antagonist" SB290157 is a Partial C5aR2 Agonist.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.591398

By:

Li, Xaria X.;
Kumar, Vinod;
Clark, Richard J.;
Lee, John D.;
Woodruff, Trent M.

Publication type:

Article

Molecular Biomarkers of Neovascular Age-Related Macular Degeneration With Incomplete Response to Anti-Vascular Endothelial Growth Factor Treatment.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.594087

By:

Mantel, Irmela;
Borgo, Angelica;
Guidotti, Jacopo;
Forestier, Edwige;
Kirsch, Olga;
Derradji, Yasmine;
Waridel, Patrice;
Burdet, Frédéric;
Mehl, Florence;
Schweizer, Claude;
Roduit, Raphaël

Publication type:

Article