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Title

It takes more than one κ opioid receptor to inhibit a POMC neuron.

Authors

Iremonger, Karl J.

Abstract

The author discusses aspects of neurons that are involved in the neural control of appetite. He explains the specific principal populations of appetite-controlling neurons involving the pro-opiomelanocortin (POMC) and the neuropeptide Y (NPY) neurons. The author adds that these neural populations have opposing actions on appetite, wherein the POMC neurons suppresses food intake, while activation of NPY neurons enhances food intake.

Subjects

NEURONS; APPETITE; PROOPIOMELANOCORTIN; NEUROPEPTIDE Y; FOOD consumption; PHYSIOLOGY

Publication

Journal of Physiology, 2013, Vol 591, Issue 7, p1595

ISSN

0022-3751

Publication type

Academic Journal

DOI

10.1113/jphysiol.2013.251637

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