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Title

Neuropeptide Y overflow and metabolism in skeletal muscle arterioles.

Authors

Evanson, Kirk W.; Stone, Audrey J.; Hammond, Allyson L.; Kluess, Heidi A.

Abstract

The article discusses a study that was aimed at characterizing neuropeptide Y (NPY) overflow and metabolism from isolated skeletal muscle arterioles of female rats. It cites the use of an isolated microvessel technique to measure this overflow. It stresses a key role being played by dipeptidyl peptidase IV (DPPIV) in regulating the actions of NPY in arterioles of young adult females, based on the results. The impact of age and other vessel characteristics on DPPIV activity is also examined.

Subjects

NEUROPEPTIDE Y; METABOLISM; ARTERIES; CD26 antigen; RATS

Publication

Journal of Physiology, 2011, Vol 589, Issue 13, p3309

ISSN

0022-3751

Publication type

Academic Journal

DOI

10.1113/jphysiol.2011.209726

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