Title: The ubiquitous ATP molecule: could it be the elusive thermal mediator igniting skin perfusion and sweating in the heat-stressed human?
Authors: González‐Alonso, José; Kalsi, Kameljit K.
Abstract: The article explores the roles of nitric oxide synthase (NOS) and cyclooxygenase (COX) in the cutaneous vascular and sweating responses to intradermal administration of adenosine triphosphate (ATP) and the contribution of adenosine to ATP-induced skin vasodilatation. Topics discussed include the association of heat stress-induced hyperthermia with increases in intravascular ATP and the physiological relevance of interstitial ATP on thermal hyperaemia.
Subjects: PHYSIOLOGICAL effects of adenosine triphosphate; NITRIC-oxide synthases; CYCLOOXYGENASES; PERSPIRATION; PHYSIOLOGICAL effects of nucleotides; PHYSIOLOGICAL effects of phosphates
Publication: Journal of Physiology, 2015, Vol 593, Issue 11, p2399
ISSN: 0022-3751
Publication type: Academic Journal
DOI: 10.1113/JP270558

The ubiquitous ATP molecule: could it be the elusive thermal mediator igniting skin perfusion and sweating in the heat-stressed human?

González‐Alonso, José; Kalsi, Kameljit K.