Works matching DE "CYCLOPAMINE"
Results: 58
Therapeutic Targeting of the Myeloma Stem Cell.
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- Current Medical Literature: Leukemia & Lymphoma, 2013, v. 21, n. 2, p. 37
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- Article
Ni(ClO<sub>4</sub>)<sub>2</sub>‐Catalyzed Friedel–Crafts Reaction of Coumarin‐Fused Donor–Acceptor Cyclopropanes with Indoles: Stereoselective Synthesis of trans‐3,4‐Disubstituted‐3,4‐dihydrocoumarins.
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- European Journal of Organic Chemistry, 2018, v. 2018, n. 30, p. 4166, doi. 10.1002/ejoc.201800669
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- Article
New Spiro‐Lactam C‐nor‐D‐homo Steroids.
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- European Journal of Organic Chemistry, 2018, v. 2018, n. 30, p. 4147, doi. 10.1002/ejoc.201800667
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- Article
Sonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases astrogliogenesis.
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- Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00077
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- Article
Hedgehog Pathway in HNSCC: A Target in Future Therapies?
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- 2011
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- Abstract
Cyclopamine-Paclitaxel-Containing Nanoparticles: Internalization in Cells Detected by Confocal and Super-Resolution Microscopy.
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- ChemPlusChem, 2015, v. 80, n. 9, p. 1380, doi. 10.1002/cplu.201500156
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- Article
Inhibition of Hedgehog signaling induces monocytic differentiation of HL-60 cells.
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- Leukemia & Lymphoma, 2012, v. 53, n. 6, p. 1196, doi. 10.3109/10428194.2011.639877
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- Article
Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma.
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- Molecular Medicine Reports, 2015, v. 12, n. 5, p. 6702, doi. 10.3892/mmr.2015.4229
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- Article
Inhibition of hedgehog signaling reduces the side population in human malignant mesothelioma cell lines.
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- Cancer Gene Therapy, 2015, v. 22, n. 8, p. 387, doi. 10.1038/cgt.2015.31
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- Article
A partial synthesis of 23-hydroxybetulonic acid and 23-hydroxybetulinic acid starting from betulinic acid.
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- Journal of Chemical Research, 2012, v. 36, n. 5, p. 254, doi. 10.3184/174751912X13332875186150
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- Article
The Hedgehog inhibitor cyclopamine impairs the benefits of immunotherapy with activated T and NK lymphocytes derived from patients with advanced cancer.
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- Cancer Immunology, Immunotherapy, 2013, v. 62, n. 6, p. 1029, doi. 10.1007/s00262-013-1419-5
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- Article
Cyclopamine Induced Expression of Immune-related Genes in Rainbow trout (Oncorhynchus mykiss) Head Kidney Leukocytes.
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- Israeli Journal of Aquaculture-Bamidgeh, 2018, v. 70, p. 1
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- Article
Native V. californicum Alkaloid Combinations Induce Differential Inhibition of Sonic Hedgehog Signaling.
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- Molecules, 2018, v. 23, n. 9, p. 2222, doi. 10.3390/molecules23092222
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- Article
Hypoxia Accelerates Aggressiveness of Hepatocellular Carcinoma Cells Involving Oxidative Stress, Epithelial-Mesenchymal Transition and Non-Canonical Hedgehog Signaling.
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- Cellular Physiology & Biochemistry (Karger AG), 2017, v. 44, n. 5, p. 1856, doi. 10.1159/000485821
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- Article
Protective Effects of Sonic Hedgehog Against Ischemia/Reperfusion Injury in Mouse Skeletal Muscle via AKT/mTOR/p70S6K Signaling.
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- Cellular Physiology & Biochemistry (Karger AG), 2017, v. 43, n. 5, p. 1813, doi. 10.1159/000484068
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- Article
Resveratrol Enhances Neurite Outgrowth and Synaptogenesis Via Sonic Hedgehog Signaling Following Oxygen-Glucose Deprivation/Reoxygenation Injury.
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- Cellular Physiology & Biochemistry (Karger AG), 2017, v. 43, n. 2, p. 852, doi. 10.1159/000481611
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- Article
Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats.
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- Cellular Physiology & Biochemistry (Karger AG), 2016, v. 39, n. 3, p. 1129, doi. 10.1159/000447820
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- Article
Cyclopamine treatment disrupts extracellular matrix and alleviates solid stress to improve nanomedicine delivery for pancreatic cancer.
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- Journal of Drug Targeting, 2018, v. 26, n. 10, p. 913, doi. 10.1080/1061186X.2018.1452243
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- Article
Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling.
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- Journal of Drug Targeting, 2012, v. 20, n. 9, p. 770, doi. 10.3109/1061186X.2012.719900
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- Article
The sonic hedgehog pathway mediates Tongxinluo capsule‐induced protection against blood‐brain barrier disruption after ischaemic stroke in mice.
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- Basic & Clinical Pharmacology & Toxicology, 2019, v. 124, n. 6, p. 660, doi. 10.1111/bcpt.13186
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- Article
Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells.
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- Oncology Letters, 2015, v. 9, n. 5, p. 1997, doi. 10.3892/ol.2015.3032
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- Article
The Hedgehog inhibitor cyclopamine antagonizes chemoresistance of breast cancer cells.
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- OncoTargets & Therapy, 2013, v. 6, p. 1643, doi. 10.2147/OTT.S51914
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- Article
Inhibitory Potential of Postnatal Treatment with Cyclopamine, a Hedgehog Signaling Inhibitor, on Medulloblastoma Development in Ptch1 Heterozygous Mice.
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- Toxicologic Pathology, 2014, v. 42, n. 8, p. 1174, doi. 10.1177/0192623314530194
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- Article
The sonic hedgehog pathway mediates brain plasticity and subsequent functional recovery after bone marrow stromal cell treatment of stroke in mice.
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- Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 7, p. 1015, doi. 10.1038/jcbfm.2013.50
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- Article
Notochord-derived hedgehog is essential for tail regeneration in Xenopus tadpole.
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- BMC Developmental Biology, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-213X-14-27
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- Article
Hedgehog signaling is activated in canine transitional cell carcinoma and contributes to cell proliferation and survival.
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- Veterinary & Comparative Oncology, 2017, v. 15, n. 1, p. 174, doi. 10.1111/vco.12149
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- Article
Establishing clones of Veratrum californicum, a native medicinal species, for micropropagation.
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- In Vitro Cellular & Developmental Biology Plant, 2014, v. 50, n. 3, p. 337, doi. 10.1007/s11627-014-9603-7
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- Article
Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development.
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- Carcinogenesis, 2013, v. 34, n. 4, p. 902
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- Article
The Effects of Inhibiting Hedgehog Signaling Pathways by Using Specific Antagonist Cyclopamine on the Chondrogenic Differentiation of Mesenchymal Stem Cells.
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- International Journal of Molecular Sciences, 2013, v. 14, n. 3, p. 5966, doi. 10.3390/ijms14035966
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- Article
Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice.
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- BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-119
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- Article
Sonic hedgehog (Shh)/Gli modulates the spatial organization of neuroepithelial cell proliferation in the developing chick optic tectum.
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- BMC Neuroscience, 2012, v. 13, n. 1, p. 1, doi. 10.1186/1471-2202-13-117
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- Article
Inhibition of early development stages of rust fungi by the two fungal metabolites cyclopaldic acid and epi-epoformin.
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- Pest Management Science, 2017, v. 73, n. 6, p. 1161, doi. 10.1002/ps.4438
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- Article
Sonic hedgehog and androgen signaling in tumor and stromal compartments drives epithelial-mesenchymal transition in prostate cancer.
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- Scandinavian Journal of Urology (Taylor & Francis Ltd), 2014, v. 48, n. 6, p. 523, doi. 10.3109/21681805.2014.898336
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- Article
Shh Signaling through the Primary Cilium Modulates Rat Oligodendrocyte Differentiation.
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- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133567
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- Article
Combination of Cyclopamine and Tamoxifen Promotes Survival and Migration of MCF-7 Breast Cancer Cells – Interaction of Hedgehog-Gli and Estrogen Receptor Signaling Pathways.
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- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114510
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- Article
Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090534
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- Article
Irradiated Riboflavin Diminishes the Aggressiveness of Melanoma In Vitroand In Vivo.
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- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054269
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- Article
Sonic Hedgehog-Signalling Patterns the Developing Chicken Comb as Revealed by Exploration of the Peacomb Mutation.
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- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050890
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- Article
Hedgehog Pathway Signaling Regulates Human Colon Carcinoma HT-29 Epithelial Cell Line Apoptosis and Cytokine Secretion.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045332
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- Article
Tissue Plasminogen Activator and Plasminogen Activator Inhibitor 1 Contribute to Sonic Hedgehog-Induced In Vitro Cerebral Angiogenesis.
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- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033444
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- Article
Inhibition of Hedgehog Signaling Antagonizes Serous Ovarian Cancer Growth in a Primary Xenograft Model.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0028077
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- Article
Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027684
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- Article
Sonic Hedgehog Pathway Is Essential for Maintenance of Cancer Stem-Like Cells in Human Gastric Cancer.
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- PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017687
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- Article
Activated hedgehog pathway is a potential target for pharmacological intervention in biliary tract cancer.
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- Molecular & Cellular Biochemistry, 2014, v. 396, n. 1/2, p. 257, doi. 10.1007/s11010-014-2161-9
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- Article
Molecular Characterization of the Hedgehog Signaling Pathway and Its Necessary Function on Larval Myogenesis in the Pacific Oyster Crassostrea gigas.
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- Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.01536
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- Article
Hedgehog signal inhibitors suppress the invasion of human rhabdomyosarcoma cells.
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- Pediatric Surgery International, 2013, v. 29, n. 11, p. 1153, doi. 10.1007/s00383-013-3369-6
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- Article
Inhibition of hedgehog signal pathway by cyclopamine attenuates inflammation and articular cartilage damage in rats with adjuvant-induced arthritis.
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- Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 7, p. 963, doi. 10.1111/jphp.12379
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- Article
Effects of cyclopamine on the biological characteristics of human breast cancer MCF-7 cell line and its mechanism.
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- European Journal of Gynaecological Oncology, 2015, v. 36, n. 4, p. 469, doi. 10.12892/ejgo2670.2015
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- Article
Sonic Hedgehog Promotes Neurite Outgrowth of Primary Cortical Neurons Through Up-Regulating BDNF Expression.
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- Neurochemical Research, 2016, v. 41, n. 4, p. 687, doi. 10.1007/s11064-015-1736-5
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- Article
The Effect of Pancreas Islet-Releasing Factors on the Direction of Embryonic Stem Cells Towards Pdx1 Expressing Cells.
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- Applied Biochemistry & Biotechnology, 2018, v. 186, n. 2, p. 371, doi. 10.1007/s12010-018-2733-3
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- Article