Works matching DE "PROTEASOME inhibitors"
Results: 1129
Sequence composition of disordered regions fine-tunes protein half-life.
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- Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 214, doi. 10.1038/nsmb.2958
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- Article
The proteasome gets a grip on protein complexity.
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- Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 181, doi. 10.1038/nsmb.2977
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- Article
Conformational switching of the 26S proteasome enables substrate degradation.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 781, doi. 10.1038/nsmb.2616
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- Article
Development of Potent and Highly Selective Epoxyketone‐Based Plasmodium Proteasome Inhibitors.
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- Chemistry - A European Journal, 2023, v. 29, n. 20, p. 1, doi. 10.1002/chem.202203958
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- Article
(Immuno)proteasomes as therapeutic target in acute leukemia.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 599, doi. 10.1007/s10555-017-9699-4
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- Article
Emerging small molecule approaches to enhance the antimyeloma benefit of proteasome inhibitors.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 585, doi. 10.1007/s10555-017-9698-5
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- Article
The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 617, doi. 10.1007/s10555-017-9700-2
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- Article
Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 717, doi. 10.1007/s10555-017-9705-x
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- Article
The proteasome and proteasome inhibitors in multiple myeloma.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 561, doi. 10.1007/s10555-017-9707-8
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- Article
Preface.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 559, doi. 10.1007/s10555-017-9706-9
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- Article
Biography-Q. Ping Dou.
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- Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 557, doi. 10.1007/s10555-017-9708-7
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- Article
The therapeutic challenge of late antibody‐mediated kidney allograft rejection.
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- Transplant International, 2019, v. 32, n. 8, p. 775, doi. 10.1111/tri.13436
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- Article
Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.
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- Acta Neuropathologica, 2012, v. 124, n. 1, p. 51, doi. 10.1007/s00401-012-0977-5
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- Article
Cancer: Targeting multiple myeloma.
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- Nature, 2015, v. 521, n. 7550, p. 8, doi. 10.1038/521008c
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- Article
Dichlorodiphenyldichloroethylene exposure reduces r-GCS via suppressed Nrf2 in HepG2 cells.
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- Environmental Toxicology, 2016, v. 31, n. 3, p. 350, doi. 10.1002/tox.22049
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- Article
Carfilzomib experience in relapsed/refractory multiple myeloma: a single-center experience.
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- Turkish Journal of Medical Sciences, 2018, v. 48, n. 1, p. 80, doi. 10.3906/sag-1611-97
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- Article
The combined effects of proteasome inhibitor bortezomib with topoisomerase I and II inhibitors on topoisomerase enzymes.
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- Turkish Journal of Medical Sciences, 2016, v. 46, n. 6, p. 1882, doi. 10.3906/sag-1511-184
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- Article
Dysfunction of the Ubiquitin Proteasome and Ubiquitin-Like Systems in Schizophrenia.
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- Neuropsychopharmacology, 2013, v. 38, n. 10, p. 1910, doi. 10.1038/npp.2013.84
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- Article
多发性骨髓瘤患者硼替佐米治疗相关带状疱疹发病机理 及预防策略研究进展
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- Progress in Modern Biomedicine, 2019, v. 19, n. 13, p. 2592, doi. 10.13241/j.cnki.pmb.2019.13.044
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- Article
The role of proteasome inhibitor MG132 in cisplatin resistant ovarian cancer.
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- European Journal of Gynaecological Oncology, 2023, v. 44, n. 4, p. 28, doi. 10.22514/ejgo.2023.055
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- Article
Disulfiram, as a candidate NF-ΚB and proteasome inhibitor, prevents endometriotic implant growing in a rat model of endometriosis.
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- European Review for Medical & Pharmacological Sciences, 2016, v. 20, n. 20, p. 4380
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- Article
Zastosowanie oksykodonu/naloksonu w terapii leczenia bólu u pacjenta ze szpiczakiem plazmocytowym.
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- Anaesthesiology & Rescue Medicine / Anestezjologia i Ratownictwo, 2016, v. 10, n. 4, p. 382
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- Article
Nocardia farcinica Brain Abscess in a Multiple Myeloma Patient Treated with Proteasome Inhibitor: A Case Report and Review of the Literature.
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- 2021
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- Case Study
Pharmacological Modulation of the Unfolded Protein Response as a Therapeutic Approach in Cutaneous T-Cell Lymphoma.
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- Biomolecules (2218-273X), 2025, v. 15, n. 1, p. 76, doi. 10.3390/biom15010076
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- Article
Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer.
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- Biomolecules (2218-273X), 2022, v. 12, n. 12, p. 1777, doi. 10.3390/biom12121777
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- Article
The Proteasome Activator PA200/PSME4: An Emerging New Player in Health and Disease.
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- Biomolecules (2218-273X), 2022, v. 12, n. 8, p. 1150, doi. 10.3390/biom12081150
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- Article
Metformin Induces Resistance of Cancer Cells to the Proteasome Inhibitor Bortezomib.
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- Biomolecules (2218-273X), 2022, v. 12, n. 6, p. 756, doi. 10.3390/biom12060756
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- Article
Editorial: Proteomic and metabolic reprogramming in myeloma cells within the tumor microenvironment.
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- Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1264740
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- Article
Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient.
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- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1130852
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- Article
Sec61 blockade therapy overrides resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma.
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- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1110916
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- Article
Proteasome-dependent senescent tumor cells mediate immunosuppression through CCL20 secretion and M2 polarization in pancreatic ductal adenocarcinoma.
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- Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1216376
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- Article
PRKX down-regulates TAK1/IRF7 signaling in the antiviral innate immunity of black carp Mylopharyngodon piceus.
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- Frontiers in Immunology, 2023, v. 13, p. 1, doi. 10.3389/fimmu.2022.999219
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- Article
Successful treatment of refractory systemic lupus erythematosus using proteasome inhibitor bortezomib followed by belimumab: description of two cases.
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- Lupus, 2017, v. 26, n. 12, p. 1333, doi. 10.1177/0961203317691371
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- Article
Manganese activates caspase-9-dependent apoptosis in human bronchial epithelial cells.
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- Human & Experimental Toxicology, 2013, v. 32, n. 11, p. 1155, doi. 10.1177/0960327112470272
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- Article
Mitogen-activated protein kinase inhibitors differently affect the growth inhibition and death of a proteasome inhibitor, MG132-treated human pulmonary fibroblast cells.
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- Human & Experimental Toxicology, 2011, v. 30, n. 12, p. 1945, doi. 10.1177/0960327111403173
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- Article
Liposomes Loaded with the Proteasome Inhibitor Z-Leucinyl-Leucinyl-Norleucinal Are Effective in Inducing Apoptosis in Colorectal Cancer Cell Lines.
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- Membranes, 2020, v. 10, n. 5, p. 91, doi. 10.3390/membranes10050091
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- Article
Understanding biology to tackle the disease: Multiple myeloma from bench to bedside, and back.
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- CA: A Cancer Journal for Clinicians, 2014, v. 64, n. 6, p. 422, doi. 10.3322/caac.21252
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- Article
Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity.
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- Thyroid, 2024, v. 34, n. 5, p. 659, doi. 10.1089/thy.2023.0514
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- Article
Oxidatively modified low‐density lipoproteins are potential mediators of proteasome inhibitor resistance in multiple myeloma.
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- International Journal of Cancer, 2021, v. 148, n. 12, p. 3032, doi. 10.1002/ijc.33497
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- Article
Proteasome inhibitors and Smac mimetics cooperate to induce cell death in diffuse large B‐cell lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis.
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- International Journal of Cancer, 2020, v. 147, n. 5, p. 1485, doi. 10.1002/ijc.32976
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- Article
The NEDD4‐1 E3 ubiquitin ligase: A potential molecular target for bortezomib sensitivity in multiple myeloma.
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- International Journal of Cancer, 2020, v. 146, n. 7, p. 1963, doi. 10.1002/ijc.32615
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- Article
Bortezomib: Safety and Efficacy in the Treatment of Multiple Myeloma.
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- Clinical Medicine Reviews in Oncology, 2010, n. 2, p. 293, doi. 10.4137/CMRO.S1631
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- Article
Allosteric regulation of the 20S proteasome by the Catalytic Core Regulators (CCRs) family.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38404-w
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- Article
Deacetylation induced nuclear condensation of HP1γ promotes multiple myeloma drug resistance.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37013-x
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- Article
The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34654-2
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- Article
Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimetics.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33461-z
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- Article
Bortezomib-Induced Cardiac Tamponade in a 49-Year-Old Man.
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- 2018
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- Publication type:
- Case Study
Identification of Long Non-Coding RNAs Deregulated in Multiple Myeloma Cells Resistant to Proteasome Inhibitors.
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- Genes, 2016, v. 7, n. 10, p. 84, doi. 10.3390/genes7100084
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- Article
Paradoxical inhibition of cellular protein expression by proteasome inhibitors.
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- Biomolecular Concepts, 2012, v. 3, n. 6, p. 593, doi. 10.1515/bmc-2012-0029
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- Article
Design, Synthesis and Evaluation of Substituted Aryl-2-Nitrovinyl Derivatives as Small Molecules Proteasome Inhibitors.
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- Iranian Journal of Pharmaceutical Research, 2018, v. 17, n. 3, p. 906
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- Article