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Title: In response: Caution in extrapolating hypercoagulable viscoelastic coagulation test results to in vivo hemostasis.
Authors: Butt, Amir L.; Ramarapu, Srikiran; Kyo, Hiroki; Tanaka, Kenichi A.
Abstract: This article discusses a case study involving a patient undergoing kidney transplantation who exhibited highly elevated functional fibrinogen on a thromboelastography (TEG) test. The authors successfully treated the condition using desmopressin, but no changes were observed in the repeat TEG test. The authors express concerns about inferring hemostatic function solely based on functional fibrinogen and highlight the need for additional laboratory coagulation data. They also discuss the potential impact of chronic kidney disease (CKD) on coagulation abnormalities and anemia, emphasizing the need for further research in this area.
Subjects: BLOOD coagulation; HEMOSTASIS; RED blood cell transfusion; CORONARY artery bypass
Publication: Transfusion, 2024, Vol 64, Issue 3, p563
ISSN: 0041-1132
Publication type: Academic Journal
DOI: 10.1111/trf.17734

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In response: Caution in extrapolating hypercoagulable viscoelastic coagulation test results to in vivo hemostasis.