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An 18‐month multimodal intervention trial for preventing dementia: J‐MINT PRIME Tamba.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 10, p. 6972, doi. 10.1002/alz.14170
By:
- Oki, Yutaro;
- Osaki, Tohmi;
- Kumagai, Ryoko;
- Murata, Shunsuke;
- Encho, Haruhi;
- Ono, Rei;
- Yasuda, Hisafumi;
- Kowa, Hisatomo
Publication type:
Article
Vascular Function in Alzheimer’s Disease and Vascular Dementia.
Published in:
American Journal of Alzheimer's Disease & Other Dementias, 2016, v. 31, n. 5, p. 437, doi. 10.1177/1533317516653820
By:
- Tachibana, Hisatsugu;
- Washida, Kazuo;
- Kowa, Hisatomo;
- Kanda, Fumio;
- Toda, Tatsushi
Publication type:
Article
Presenilin-1 C410Y Alzheimer Disease Plaques Contain Synaptic Proteins.
Published in:
American Journal of Alzheimer's Disease & Other Dementias, 2007, v. 22, n. 2, p. 137, doi. 10.1177/1533317506298051
By:
- Kamran Haleem;
- Lippa, Carol F.;
- Smith, Thomas W.;
- Hisatomo Kowa;
- Jianlin Wu;
- Takeshi Iwatsubo
Publication type:
Article
GGA1 Acts as a Spatial Switch Altering Amyloid Precursor Protein Trafficking and Processing.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 39, p. 9913, doi. 10.1523/JNEUROSCI.2290-06.2006
By:
- Von Arnim, Christine A. F.;
- Spoelgen, Robert;
- Peltan, Ithan D.;
- Deng, Meihua;
- Courchesne, Stephanie;
- Koker, Mirjam;
- Matsui, Toshifumi;
- Kowa, Hisatomo;
- Lichtenthaler, Stefan F.;
- Irizarry, Michael C.;
- Hyman, Bradley T.
Publication type:
Article
A japanese family carrying a novel mutation in the emery-dreifuss muscular dystrophy gene.
Published in:
Annals of Neurology, 1997, v. 41, n. 3, p. 399, doi. 10.1002/ana.410410316
By:
- Ichikawa, Yaeko;
- Watanabe, Masahiko;
- Kowa, Hisatomo;
- Murayama, Shigeo;
- Mizuno, Takehiko;
- Komuro, Issei;
- Ishiki, Ryouji;
- Goto, Jun;
- Kanazawa, Ichiro
Publication type:
Article
Combining plasma Aβ and p-tau217 improves detection of brain amyloid in non-demented elderly.
Published in:
Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01469-w
By:
- Niimi, Yoshiki;
- Janelidze, Shorena;
- Sato, Kenichiro;
- Tomita, Naoki;
- Tsukamoto, Tadashi;
- Kato, Takashi;
- Yoshiyama, Kenji;
- Kowa, Hisatomo;
- Iwata, Atsushi;
- Ihara, Ryoko;
- Suzuki, Kazushi;
- Kasuga, Kensaku;
- Ikeuchi, Takeshi;
- Ishii, Kenji;
- Ito, Kengo;
- Nakamura, Akinori;
- Senda, Michio;
- Day, Theresa A.;
- Burnham, Samantha C.;
- Iaccarino, Leonardo
Publication type:
Article
Action-rule-based cognitive control enables efficient execution of stimulus-response conflict tasks: a model validation of Simon task performance.
Published in:
Frontiers in Human Neuroscience, 2023, p. 1, doi. 10.3389/fnhum.2023.1239207
By:
- Yoshitaka Otani;
- Yoshitada Katagiri;
- Emiko Imai;
- Hisatomo Kowa
Publication type:
Article
CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV.
Published in:
EMBO Journal, 2002, v. 21, n. 7, p. 1524, doi. 10.1093/emboj/21.7.1524
By:
- Hashimoto, Tadafumi;
- Wakabayashi, Tomoko;
- Watanabe, Atsushi;
- Kowa, Hisatomo;
- Hosoda, Ritsuko;
- Nakamura, Atsushi;
- Kanazawa, Ichiro;
- Arai, Takao;
- Takio, Koji;
- Mann, David M.A.;
- Iwatsubo, Takeshi
Publication type:
Article
Changes in cognitive functioning by a multifactorial intervention to prevent dementia‐The Japan‐Multimodal Intervention Trial for Prevention of Dementia PRIME Tamba‐.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077614
By:
- Oki, Yutaro;
- Osaki, Tohmi;
- Murata, Shunsuke;
- Kumagai, Ryoko;
- Encho, Haruhi;
- Ono, Rei;
- Yasuda, Hisafumi;
- Kowa, Hisatomo
Publication type:
Article
Efficacy and Safety of Cilostazol in Mild Cognitive Impairment: A Randomized Clinical Trial.
Published in:
JAMA Network Open, 2023, v. 6, n. 12, p. e2344938, doi. 10.1001/jamanetworkopen.2023.44938
By:
- Saito, Satoshi;
- Suzuki, Keisuke;
- Ohtani, Ryo;
- Maki, Takakuni;
- Kowa, Hisatomo;
- Tachibana, Hisatsugu;
- Washida, Kazuo;
- Kawabata, Nobuya;
- Mizuno, Toshiki;
- Kanki, Rie;
- Sudoh, Shinji;
- Kitaguchi, Hiroshi;
- Shindo, Katsuro;
- Shindo, Akihiro;
- Oka, Nobuyuki;
- Yamamoto, Keiichi;
- Yasuno, Fumihiko;
- Kakuta, Chikage;
- Kakuta, Ryosuke;
- Yamamoto, Yumi
Publication type:
Article
Dorsal Anterior Cingulate Cortex Coordinates Contextual Mental Imagery for Single-Beat Manipulation during Rhythmic Sensorimotor Synchronization.
Published in:
Brain Sciences (2076-3425), 2024, v. 14, n. 8, p. 757, doi. 10.3390/brainsci14080757
By:
- Uemura, Maho;
- Katagiri, Yoshitada;
- Imai, Emiko;
- Kawahara, Yasuhiro;
- Otani, Yoshitaka;
- Ichinose, Tomoko;
- Kondo, Katsuhiko;
- Kowa, Hisatomo
Publication type:
Article
Immunotherapy-responsive Non-paraneoplastic Encephalitis with Antibodies against GAD, LGI1, and GABAA Receptor.
Published in:
Internal Medicine, 2022, v. 61, n. 3, p. 419, doi. 10.2169/internalmedicine.7846-21
By:
- Takahiro Nakano;
- Norio Chihara;
- Kento Matoba;
- Hisatsugu Tachibana;
- Shiho Okuda;
- Yoshihisa Otsuka;
- Takehiro Ueda;
- Kenji Sekiguchi;
- Hisatomo Kowa;
- Frank Leypoldt;
- Klaus-Peter Wandinger;
- Riki Matsumoto
Publication type:
Article
Wide distribution of alpha-synuclein oligomers in multiple system atrophy brain detected by proximity ligation.
Published in:
Acta Neuropathologica, 2019, v. 137, n. 3, p. 455, doi. 10.1007/s00401-019-01961-w
By:
- Sekiya, Hiroaki;
- Kowa, Hisatomo;
- Koga, Hinako;
- Takata, Mariko;
- Satake, Wataru;
- Futamura, Naonobu;
- Funakawa, Itaru;
- Jinnai, Kenji;
- Takahashi, Motonori;
- Kondo, Takeshi;
- Ueno, Yasuhiro;
- Kanagawa, Motoi;
- Kobayashi, Kazuhiro;
- Toda, Tatsushi
Publication type:
Article
Survey on the current situation for early diagnosis of dementia and contributing factors in Japan.
Published in:
Psychogeriatrics, 2024, v. 24, n. 2, p. 312, doi. 10.1111/psyg.13075
By:
- Kumagai, Ryoko;
- Sonoda, Yuma;
- Kowa, Hisatomo
Publication type:
Article
Eight months observation of check‐up system 'Kobe dementia model' of dementia in Kobe City.
Published in:
Psychogeriatrics, 2021, v. 21, n. 2, p. 246, doi. 10.1111/psyg.12649
By:
- Yoshino, Hiroshi;
- Kowa, Hisatomo;
- Maeda, Kiyoshi;
- Takechi, Hajime
Publication type:
Article
Dopamine transporter imaging as a diagnostic modality for atypical Alzheimer's disease mimicking corticobasal degeneration.
Published in:
2017
By:
- Washida, Kazuo;
- Kowa, Hisatomo;
- Yamamoto, Yasuji;
- Kanda, Fumio;
- Toda, Tatsushi
Publication type:
Other
Molecular pathology of Sandhoff disease with p.Arg505Gln in HEXB: application of simulation analysis.
Published in:
Journal of Human Genetics, 2013, v. 58, n. 9, p. 611, doi. 10.1038/jhg.2013.68
By:
- Yasui, Naoko;
- Takaoka, Yutaka;
- Nishio, Hisahide;
- Nurputra, Dian K;
- Sekiguchi, Kenji;
- Hamaguchi, Hirotoshi;
- Kowa, Hisatomo;
- Maeda, Eiichi;
- Sugano, Aki;
- Miura, Kenji;
- Sakaeda, Toshiyuki;
- Kanda, Fumio;
- Toda, Tatsushi
Publication type:
Article
Implication of using cognitive function-related simple questions to stratify the risk of long-term care need: population-based prospective study in Kobe, Japan.
Published in:
2022
By:
- Kojima, Shinsuke;
- Kikuchi, Takashi;
- Kakei, Yasumasa;
- Kowa, Hisatomo;
- Yamamoto, Yasuji;
- Kajita, Hiroyuki;
- Osaki, Tohmi;
- Fukushima, Masanori;
- Kayano, Ryoma;
- Nagai, Yoji
Publication type:
journal article
Brain uptake and safety of Flutemetamol F 18 injection in Japanese subjects with probable Alzheimer's disease, subjects with amnestic mild cognitive impairment and healthy volunteers.
Published in:
2017
By:
- Miki, Takami;
- Shimada, Hiroyuki;
- Kim, Jae-Seung;
- Yamamoto, Yasuji;
- Sugino, Masakazu;
- Kowa, Hisatomo;
- Heurling, Kerstin;
- Zanette, Michelle;
- Sherwin, Paul;
- Senda, Michio;
- Sherwin, Paul F
Publication type:
journal article
Self Assessment Memory Scale (SAMS), a new simple method for evaluating memory function.
Published in:
Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.1024497
By:
- Hisatomo Kowa;
- Maki Uchimura;
- Asuka Ohashi;
- Mamoru Hiroe;
- Rei Ono
Publication type:
Article
A Study of the Usefulness of Self‐Assessment Memory Scale (SAMS) for the Elderly in the Community.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076497
By:
- Kowa, Hisatomo;
- Oki, Yutaro;
- Imamura, Miki;
- Suzuki, Yuka
Publication type:
Article
Framework for disclosing AD biomarker results following cognitive assessment within a pragmatic, multi‐country implementation evaluation.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.063746
By:
- MacLeod, Tim;
- Baksh, Magda Ruth;
- Filho, Otelo Corrêa dos Santos;
- Govia, Ishtar;
- Robledo, Luis Miguel Gutierrez;
- Kowa, Hisatomo;
- Ritchie, Craig W.;
- Willis, Deanna R;
- Coppinger, Justine;
- Ball, Daniel E;
- Murray, James F;
- Largent, Emily A.
Publication type:
Article
Baseline characteristics in Japan‐multimodal intervention trial for prevention of dementia (J‐MINT) Tamba study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.053802
By:
- Ono, Rei;
- Kowa, Hisatomo;
- Oki, Yutaro;
- Osaki, Tohmi;
- Murata, Shunsuke;
- Kumagai, Ryoko;
- Uchida, Kazuaki;
- Yasuda, Hisafumi;
- Kido, Yoshiaki
Publication type:
Article
Usefulness of the self‐reported Dementia Assessment Sheet for Community‐based Integrated Care System‐21 items (DASC‐21) in the community‐dwelling elderly: Epidemiology / Innovative methods in epidemiology (i.e., assessment methods, design, recruitment strategies, statistical methods, etc.)
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041652
By:
- Ono, Rei;
- Uchida, Kazuaki;
- Kawaharada, Rika;
- Kido, Yoshiaki;
- Yasuda, Hisafumi;
- Kowa, Hisatomo
Publication type:
Article
P3‐593: A CROSS‐OVER RANDOMIZED CONTROLLED TRIAL OF SHORT‐TERM MULTICOMPONENT EXERCISE PROGRAM CONDUCTED AMONG COMMUNITY‐DWELLING HEALTHY ELDERLY PEOPLE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1202, doi. 10.1016/j.jalz.2019.06.3630
By:
- Kowa, Hisatomo;
- Ono, Rei;
- Murata, Shunsuke;
- Yasuda, Hisafumi;
- Tanemura, Rumi;
- Kido, Yoshiaki
Publication type:
Article
The early detection of cognitive deterioration in normal populations attending medical checkups of the brain
Published in:
2010
By:
- Suzuki, Kazushi;
- Kowa, Hisatomo;
- Oike, Yumiko;
- Seto, Motoko;
- Aizawa, Kenichi;
- Suzuki, Toru;
- Yamazaki, Tsutomu;
- Tsuji, Shoji;
- Iwata, Atsushi
Publication type:
Abstract
A family of dementia, leukoencephalopathy, tremor, peripheral neuropathy and retinitis pigmentosa: A clinical description
Published in:
2010
By:
- Ohtomo, Ryo;
- Shirota, Yuichiro;
- Ishiura, Hiroyuki;
- Kowa, Hisatomo;
- Tsuji, Shoji;
- Iwata, Atsushi
Publication type:
Abstract
The clinical characteristics of the Japanese pedigree of FAD with PS1 H163R mutation
Published in:
2009
By:
- Miyagawa, Toji;
- Iwata, Atsushi;
- Kowa, Hisatomo;
- Kawarabayashi, Takeshi;
- Shoji, Mikio;
- Tsuji, Shoji;
- Momose, Toshimitsu;
- Kojima, Yoshiki
Publication type:
Abstract
P2-194: Complement pathways are upregulated in angular gyrus of primary progressive aphasia cases
Published in:
2008
By:
- Kowa, Hisatomo;
- Matsui, Toshifumi;
- Bouzou, Bérengère;
- Clark, Tim;
- Freeman, Stefanie;
- Frosch, Matthew;
- Hyman, Bradley
Publication type:
Abstract
P4-079: Coordinated expression of APP pathway mRNA and protein in AD
Published in:
2006
By:
- Matsui, Toshifumi;
- Ingelsson, Martin;
- Fukumoto, Hiroaki;
- Ramasamy, Karunya;
- Kowa, Hisatomo;
- Frosch, Matthew P.;
- Irizarry, Michael C.;
- Hyman, Bradley T.
Publication type:
Abstract
P4-079: Coordinated expression of APP pathway mRNA and protein in AD
Published in:
2006
By:
- Matsui, Toshifumi;
- Ingelsson, Martin;
- Fukumoto, Hiroaki;
- Ramasamy, Karunya;
- Kowa, Hisatomo;
- Frosch, Matthew P.;
- Irizarry, Michael C.;
- Hyman, Bradley T.
Publication type:
Abstract
Japanese WDR45 de novo mutation diagnosed by exome analysis: A case report.
Published in:
Neurology & Clinical Neuroscience, 2017, v. 5, n. 4, p. 131, doi. 10.1111/ncn3.12132
By:
- Endo, Hironobu;
- Uenaka, Takeshi;
- Satake, Wataru;
- Suzuki, Yutaka;
- Tachibana, Hisatsugu;
- Chihara, Norio;
- Ueda, Takehiro;
- Sekiguchi, Kenji;
- Mariko, Taniguchi‐Ikeda;
- Kowa, Hisatomo;
- Kanda, Fumio;
- Toda, Tatsushi
Publication type:
Article
Discrepancy between distribution of alpha-synuclein oligomers and Lewy-related pathology in Parkinson's disease.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01440-6
By:
- Sekiya, Hiroaki;
- Tsuji, Asato;
- Hashimoto, Yuki;
- Takata, Mariko;
- Koga, Shunsuke;
- Nishida, Katsuya;
- Futamura, Naonobu;
- Kawamoto, Michi;
- Kohara, Nobuo;
- Dickson, Dennis W.;
- Kowa, Hisatomo;
- Toda, Tatsushi
Publication type:
Article
7 Self Assessment Memory Scale, a new simple method for evaluating memory function.
Published in:
2023
By:
- Kowa, Hisatomo
Publication type:
Abstract
Association between locomotive syndrome and anemia among community‐dwelling older adults.
Published in:
Geriatrics & Gerontology International, 2023, v. 23, n. 6, p. 426, doi. 10.1111/ggi.14593
By:
- Encho, Haruhi;
- Uchida, Kazuaki;
- Nakamura, Junya;
- Mizuta, Sachiko;
- Akisue, Toshihiro;
- Kowa, Hisatomo;
- Ono, Rei
Publication type:
Article
Less Limb Muscle Involvement in Myositis Patients with Anti-Mitochondrial Antibodies.
Published in:
European Neurology, 2017, v. 78, n. 5/6, p. 290, doi. 10.1159/000481503
By:
- Uenaka, Takeshi;
- Kowa, Hisatomo;
- Ohtsuka, Yoshihisa;
- Seki, Tsuneyoshi;
- Sekiguchi, Kenji;
- Kanda, Fumio;
- Toda, Tatsushi
Publication type:
Article
Adult-onset leukoencephalopathies with vanishing white matter with novel missense mutations in EIF2B2, EIF2B3, and EIF2B5.
Published in:
2011
By:
- Matsukawa, Takashi;
- Wang, Xuemin;
- Liu, Rui;
- Wortham, Noel;
- Onuki, Yuko;
- Kubota, Akatsuki;
- Hida, Ayumi;
- Kowa, Hisatomo;
- Fukuda, Yoko;
- Ishiura, Hiroyuki;
- Mitsui, Jun;
- Takahashi, Yuji;
- Aoki, Shigeki;
- Takizawa, Shunya;
- Shimizu, Jun;
- Goto, Jun;
- Proud, Christopher;
- Tsuji, Shoji
Publication type:
Letter
Severe hypokinesis caused by paraneoplastic anti-Ma2 encephalitis associated with bilateral intratubular germ-cell neoplasm of the testes.
Published in:
2007
By:
- Matsumoto, Lumine;
- Yamamoto, Tomotaka;
- Higashihara, Mana;
- Sugimoto, Izumi;
- Kowa, Hisatomo;
- Shibahara, Junji;
- Nakamura, Koichiro;
- Shimizu, Jun;
- Ugawa, Yoshikazu;
- Goto, Jun;
- Dalmau, Josep;
- Tsuji, Shoji
Publication type:
journal article
Myositis with antimitochondrial antibodies diagnosed by rectus abdominis muscle biopsy.
Published in:
Muscle & Nerve, 2013, v. 47, n. 5, p. 766, doi. 10.1002/mus.23730
By:
- Uenaka, Takeshi;
- Kowa, Hisatomo;
- Sekiguchi, Kenji;
- Nagata, Kakuya;
- Ohtsuka, Yoshihisa;
- Kanda, Fumio;
- Toda, Tatsushi
Publication type:
Article

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