The article discusses the negative symptoms of schizophrenia, such as flat affect and social withdrawal, and their economic impact on healthcare in the United States. It highlights a study by Yeh et al. on the efficacy of high-definition transcranial direct current stimulation (HD-tDCS) in alleviating these symptoms. The study found that HD-tDCS improved negative symptoms in a larger sample size, offering a new treatment option for patients who do not respond to pharmacotherapy. This research is significant for developing effective treatments for schizophrenia's negative symptoms and improving clinical outcomes.