The authors were appropriately concerned about amnesia and hypnosis in the sevoflurane-free group and used processed EEG monitoring, claiming that it indicated likely adequate hypnosis. Despite the lack of explicit memory concerns, stress and pain in infants may result in lasting behavioral change.5 In fact, the data reported by Efune and colleagues argue that the sevoflurane-free group had inadequate hypnosis. In conclusion, a mainstay of anesthesia practice in our era is ensuring analgesia, amnesia, and hypnosis.