ODSS vs. ABSIS and PDAI oral parts in pemphigus vulgaris: inter‐rater reliability and testing times.

Shamabadi, Ahmad; Yazdinezhad, Soodeh; Sadeghi, Yasaman; Moradi, Amir Reza; Yazdchi, Arsalan; Teymourpour, Amir; Faramarzi, Atefeh; Seirafi, Ramtin; Balighi, Kamran; Mahmoudi, Hamidreza; Daneshpazhooh, Maryam

Objectives: The existence of standard methods for diagnosis and measuring the severity of diseases leads to a more accurate severity assessment, the possibility of following up, and the possibility of comparing the results of studies. This study aimed to compare different pemphigus vulgaris (PV) assessment methods regarding inter‐observer reliability and testing times—focusing on oral parts. Materials and Methods: Two dermatologists evaluated orally involved PV patients by oral parts of Autoimmune Bullous Skin Disorder Intensity Score (ABSIS), Pemphigus Disease Area Index (PDAI), and Oral Disease Severity Score (ODSS). Results: Seventy patients completed the study. The intraclass correlation coefficient showed the evaluators' agreements on ABSIS, PDAI, and ODSS with 0.98, 0.94, and 0.95, respectively. Reliability analyses showed near‐perfect relationships between each scoring methods pairs. There was no association between lesion sites and disease severity. The PDAI scoring duration was significantly shorter, and the ABSIS scoring duration was significantly longer. Conclusion: ODSS is valid for evaluating oral involvement in patients with PV and relates to ABSIS and PDAI almost perfectly. Besides, it was shown that the evaluation of patients' oral involvement based on PDAI and ODSS is done in about 1 min, which seems clinically reasonable.

PEMPHIGUS diagnosis; ORAL disease diagnosis; RESEARCH; RESEARCH methodology evaluation; RESEARCH methodology; SEVERITY of illness index; COMPARATIVE studies; INTER-observer reliability; INTRACLASS correlation; DESCRIPTIVE statistics; RESEARCH bias; STATISTICAL correlation; EVALUATION

Oral Diseases, 2023, Vol 29, Issue 7, p2696

1354-523X

Academic Journal

10.1111/odi.14320