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Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Characterization of mice doubly transgenic for parathyroid hormone-related protein and murine placental lactogen: a novel role for placental lactogen in pancreatic beta-cell survival.
- Published in:
- 2004
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- Publication type:
- journal article
Overexpression of parathyroid hormone-related protein inhibits pancreatic beta-cell death in vivo and in vitro.
- Published in:
- 2002
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- Publication type:
- journal article
Lambert–Eaton myasthenic syndrome: mouse passive‐transfer model illuminates disease pathology and facilitates testing therapeutic leads.
- Published in:
- Annals of the New York Academy of Sciences, 2018, v. 1412, n. 1, p. 73, doi. 10.1111/nyas.13512
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- Publication type:
- Article
Author Correction: Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32162-x
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- Publication type:
- Article
Targeted delivery of HGF to the skeletal muscle improves glucose homeostasis in diet-induced obese mice.
- Published in:
- Journal of Physiology & Biochemistry, 2015, v. 71, n. 4, p. 795, doi. 10.1007/s13105-015-0444-6
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- Publication type:
- Article
"RAS"ling β cells to proliferate for diabetes: why do we need MEN?
- Published in:
- Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3698, doi. 10.1172/JCI77764
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- Publication type:
- Article
Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic β-cell replication in mice.
- Published in:
- Journal of Physiology, 2008, v. 586, n. 3, p. 899, doi. 10.1113/jphysiol.2007.143586
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- Publication type:
- Article
A comparison of parathyroid hormone-related protein (1-36) and parathyroid hormone (1-34) on markers of bone turnover and bone density in postmenopausal women: The PrOP study.
- Published in:
- Journal of Bone & Mineral Research, 2013, v. 28, n. 11, p. 2266, doi. 10.1002/jbmr.1978
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- Publication type:
- Article
A 7-day continuous infusion of PTH or PTHrP suppresses bone formation and uncouples bone turnover.
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- Journal of Bone & Mineral Research, 2011, v. 26, n. 9, p. 2287, doi. 10.1002/jbmr.415
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- Publication type:
- Article
Continuous PTH and PTHrP Infusion Causes Suppression of Bone Formation and Discordant Effects on 1,25(OH)<sub>2</sub>Vitamin D.
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- Journal of Bone & Mineral Research, 2005, v. 20, n. 10, p. 1792, doi. 10.1359/JBMR.050602
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- Publication type:
- Article
C-Terminal Parathyroid Hormone-Related Protein Inhibits Proliferation and Differentiation of Human Osteoblast-like Cells.
- Published in:
- Journal of Bone & Mineral Research, 1997, v. 12, n. 5, p. 778, doi. 10.1359/jbmr.1997.12.5.778
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- Publication type:
- Article
Parathyroid hormone-related protein is an autocrine modulator of rabbit proximal tubule cell growth.
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- Journal of Bone & Mineral Research, 1995, v. 10, n. 12, p. 1875, doi. 10.1002/jbmr.5650101206
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- Publication type:
- Article
A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
- Published in:
- Nature Medicine, 2015, v. 21, n. 4, p. 383, doi. 10.1038/nm.3820
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- Publication type:
- Article
Improving islet transplantation by gene delivery of hepatocyte growth factor (HGF) and its downstream target, protein kinase B (PKB)/Akt.
- Published in:
- Cell Biochemistry & Biophysics, 2007, v. 48, n. 2/3, p. 191, doi. 10.1007/s12013-007-0024-7
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- Publication type:
- Article
NRF2 is required for neonatal mouse beta cell growth by maintaining redox balance and promoting mitochondrial biogenesis and function.
- Published in:
- Diabetologia, 2024, v. 67, n. 3, p. 547, doi. 10.1007/s00125-023-06071-7
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- Publication type:
- Article
Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles.
- Published in:
- Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01179-2
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- Publication type:
- Article
Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion during Acute Sepsis in Non-Diabetic Mice.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067716
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- Publication type:
- Article
A Phase 1 single ascending dose study of pure oral harmine in healthy volunteers.
- Published in:
- Journal of Psychopharmacology, 2024, v. 38, n. 10, p. 911, doi. 10.1177/02698811241273772
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- Publication type:
- Article
Parathyroid hormone-related protein for the treatment of postmenopausal osteoporosis: defining the maximal tolerable dose.
- Published in:
- 2010
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- Publication type:
- journal article
Direct Comparison of Sustained Infusion of Human Parathyroid Hormone-Related Protein-(1–36) [hPTHrP(1–36)] Versus hPTH-(1–34) on Serum Calcium, Plasma 1,25-Dihydroxyvitamin D Concentrations, and Fractional Calcium Excretion in Healthy Human Volunteers.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 4, p. 1603, doi. 10.1210/jc.2002-020773
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- Publication type:
- Article
Short-Term, High-Dose Parathyroid Hormone-Related Protein as a Skeletal Anabolic Agent for the Treatment of Postmenopausal Osteoporosis.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 2, p. 569, doi. 10.1210/jc.2002-021122
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- Publication type:
- Article
Parathyroid Hormone-Related Protein-(1–36) Stimulates Renal Tubular Calcium Reabsorption in Normal Human Volunteers: Implications for the Pathogenesis of Humoral Hypercalcemia of Malignancy.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 4, p. 1525, doi. 10.1210/jcem.86.4.7406
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- Publication type:
- Article
Using β-Cell Growth Factors to Enhance Human Pancreatic Islet Transplantation.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 3, p. 984, doi. 10.1210/jcem.86.3.7315
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- Publication type:
- Article
Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges.
- Published in:
- Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.671946
- By:
- Publication type:
- Article
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 530, p. 1, doi. 10.1126/scitranslmed.aaw9996
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- Publication type:
- Article
Intermittent Hypoxia Causes Insulin Resistance in Lean Mice Independent of Autonomic Activity.
- Published in:
- American Journal of Respiratory & Critical Care Medicine, 2007, v. 175, n. 8, p. 851, doi. 10.1164/rccm.200610-1527oc
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- Publication type:
- Article
Safety and tolerability of subcutaneous PTHrP(1–36) in healthy human volunteers: a dose escalation study.
- Published in:
- Osteoporosis International, 2006, v. 17, n. 2, p. 225, doi. 10.1007/s00198-005-1976-3
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- Publication type:
- Article
Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.
- Published in:
- Science Signaling, 2019, v. 12, n. 610, p. 1, doi. 10.1126/scisignal.aax0715
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- Publication type:
- Article
Parathyroid Hormone-Related Peptide (1-36) Enhances Beta Cell Regeneration and Increases Beta Cell Mass in a Mouse Model of Partial Pancreatectomy.
- Published in:
- PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0158414
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- Publication type:
- Article
Hepatocyte Growth Factor Enhances Engraftment and Function of Nonhuman Primate Islets.
- Published in:
- Diabetes, 2008, v. 57, n. 10, p. 2745, doi. 10.2337/db08-1085
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- Publication type:
- Article
Protein Kinase C-ζ Activation Markedly Enhances ß-Cell Proliferation.
- Published in:
- Diabetes, 2007, v. 56, n. 11, p. 2732, doi. 10.2337/db07-0461
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- Publication type:
- Article
Glucose infusion in mice: a new model to induce beta-cell replication.
- Published in:
- 2007
- By:
- Publication type:
- journal article
Glucose Infusion in Mice.
- Published in:
- Diabetes, 2007, v. 56, n. 7, p. 1792, doi. 10.2337/db06-1513
- By:
- Publication type:
- Article
Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Targeted Inactivation of Hepatocyte Growth Factor Receptor c-met in β-Cells Leads to Defective Insulin Secretion and GLUT-2 Downregulation Without Alteration of β-Cell Mass.
- Published in:
- Diabetes, 2005, v. 54, n. 7, p. 2090, doi. 10.2337/diabetes.54.7.2090
- By:
- Publication type:
- Article
Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice.
- Published in:
- 2001
- By:
- Publication type:
- journal article
Antiproliferative effect of the C-terminal fragments of parathyroid hormone-related protein, PTHrP-(107-111) and (107-139), on osteoblastic osteosarcoma cells.
- Published in:
- Journal of Cellular Physiology, 1997, v. 170, n. 2, p. 209, doi. 10.1002/(SICI)1097-4652(199702)170:2<209::AID-JCP13>3.0.CO;2-C
- By:
- Publication type:
- Article
Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia.
- Published in:
- European Journal of Applied Physiology, 2013, v. 113, n. 2, p. 467, doi. 10.1007/s00421-012-2452-3
- By:
- Publication type:
- Article
Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges.
- Published in:
- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2021.671946
- By:
- Publication type:
- Article
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system.
- Published in:
- Science Translational Medicine, 2024, v. 16, n. 755, p. 1, doi. 10.1126/scitranslmed.adg3456
- By:
- Publication type:
- Article
A Comparison of Parathyroid Hormone-Related Protein (1-36) and Parathyroid Hormone (1-34) on Markers of Bone Turnover and Bone Density in Postmenopausal Women: The PrOP Study.
- Published in:
- Journal of Bone & Mineral Research, 2014, v. 29, n. 3, p. 770, doi. 10.1002/jbmr.2149
- By:
- Publication type:
- Article
Simultaneous Measurement of Insulin Sensitivity, Insulin Secretion, and the Disposition Index in Conscious Unhandled Mice.
- Published in:
- Obesity (19307381), 2012, v. 20, n. 7, p. 1403, doi. 10.1038/oby.2012.36
- By:
- Publication type:
- Article
Nrf2 Regulates β-Cell Mass by Suppressing β-Cell Death and Promoting β-Cell Proliferation.
- Published in:
- 2022
- By:
- Publication type:
- journal article
638-P: A Novel, Long-Acting Dual Agonist for GIPR/GLP-1R, HISHS-2001, Demonstrates Effects on HbA1c and Weight Loss in the db/db Mouse Model of Type 2 Diabetes.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-638-P
- By:
- Publication type:
- Article
Dextran Sulfate Protects Pancreatic β-Cells, Reduces Autoimmunity, and Ameliorates Type 1 Diabetes.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Lactogens Reduce Endoplasmic Reticulum Stress-Induced Rodent and Human β-Cell Death and Diabetes Incidence in Akita Mice.
- Published in:
- 2020
- By:
- Publication type:
- journal article
1784-P: Liraglutide Treatment Stimulates Alpha Cells to Produce Glucagon-Like Peptide-1 via Expression of Prohormone Convertase 1/3 in Mice and Human.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1784-P
- By:
- Publication type:
- Article
Myc Is Required for Adaptive β-Cell Replication in Young Mice but Is Not Sufficient in One-Year-Old Mice Fed With a High-Fat Diet.
- Published in:
- 2019
- By:
- Publication type:
- journal article