We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Difference between kidney function by cystatin C versus creatinine and association with muscle mass and frailty.
- Authors
Yuan, Julia H; Rifkin, Dena E; Ginsberg, Charles; Cawthon, Peggy M; Kado, Deborah M; Bauer, Scott R; Ensrud, Kristine E; Hoffman, Andrew R; Potok, O Alison
- Abstract
A higher difference in estimated glomerular filtration rate by cystatin C versus creatinine (eGFRDiff = eGFRCys - eGFRCreat) is associated with decreased frailty risk. Since eGFRCreat is influenced by muscle more than eGFRCys, muscle mass may explain this association. Previous work could not account for this when considering regional muscle measures by imaging. Deuterated creatine (D 3 Cr) dilution measures whole body muscle mass (kilograms). We aimed to determine whether eGFRDiff is associated with D 3 Cr muscle mass and whether muscle mass explains the association between eGFRDiff and frailty.
- Publication
Journal of the American Geriatrics Society, 2024, Vol 72, Issue 10, p3163
- ISSN
1532-5415
- Publication type
Journal Article
- DOI
10.1111/jgs.19014