Outcomes reporting in clinical trials of Chinese herbal medicine on ulcerative colitis: A systematic review.

Zhang, Xuan; Zhang, Lin; Wang, Juan; Hu, Lihan; Zhang, Xuanqi; Wang, Nana; Tan, Hanzhi; Cheng, Chung Wah; Li, Ji; Han, Fei; Wang, Ping; Lyu, Aiping; Bian, Zhaoxiang

The systematic review published in the Journal of Evidence-Based Medicine focuses on outcomes reporting in clinical trials of Chinese herbal medicine for ulcerative colitis (UC). The study highlights the challenges in standardizing outcome measures due to the lack of agreed-upon evaluation criteria, such as those in Chinese medicine. The review aims to summarize existing endpoint definitions, measurement tools, and efficacy outcomes reported in randomized controlled trials of Chinese herbal medicine for UC, emphasizing the need for a core outcome set to reduce heterogeneity and enhance study quality. The study included 1247 randomized controlled trials published between 2011 and 2022, with outcomes categorized into domains such as clinical composite outcomes, safety outcomes, CM symptoms/patterns outcomes, and others.

CELL adhesion molecules; END of treatment; HAMILTON Depression Inventory; INFLAMMATORY bowel diseases; TREATMENT effectiveness; ENEMA; CONDOM use; PLATELET function tests

Journal of Evidence-Based Medicine, 2024, Vol 17, Issue 4, p691

1756-5383

Academic Journal

10.1111/jebm.12649