Works matching DE "HEPATOCYTE nuclear factors"

Results: 415

Hepatocyte Nuclear Factor 4 Alpha: A Key Regulator of Liver Disease Pathology and Haemostatic Disorders.

Published in:

Liver International, 2025, v. 45, n. 6, p. 1, doi. 10.1111/liv.16245

By:

Choudhuri, Subhadip;
Garg, Nisha Jain

Publication type:

Article

Association study of HNF1A in women with polycystic ovary syndrome.

Published in:

Journal of Assisted Reproduction & Genetics, 2017, v. 34, n. 5, p. 677, doi. 10.1007/s10815-017-0905-7

By:

Lv, Yue;
Sun, Changfa;
Tian, Ye;
Zhao, Shigang;
Bian, Yuehong;
Cheng, Lei;
Sun, Mei;
Liu, Hong-Bin;
Zhao, Han;
Ma, Jinlong

Publication type:

Article

Cell-permeated peptide P-T3H2 inhibits malignancy on hepatocellular carcinoma through stabilizing HNF4α protein.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01661-2

By:

Wu, Si-Han;
Xiao, Meng-Chao;
Liu, Fang;
Hong, Huan-Yu;
Ding, Chen-Hong;
Zhang, Xin;
Xie, Wei-Fen

Publication type:

Article

Inverse regulation of claudin-2 and -7 expression by p53 and hepatocyte nuclear factor 4α in colonic MCE301 cells.

Published in:

Tissue Barriers, 2021, v. 9, n. 1, p. 1, doi. 10.1080/21688370.2020.1860409

By:

Hirota, Chieko;
Takashina, Yui;
Ikumi, Naotaka;
Ishizuka, Noriko;
Hayashi, Hisayoshi;
Tabuchi, Yoshiaki;
Yoshino, Yuta;
Matsunaga, Toshiyuki;
Ikari, Akira

Publication type:

Article

LINC00667 regulates MPP<sup>+</sup>‐induced neuronal injury in Parkinson's disease.

Published in:

Annals of Clinical & Translational Neurology, 2022, v. 9, n. 5, p. 707, doi. 10.1002/acn3.51480

By:

Huo, Xinlong;
Wang, Lisong;
Shao, Jiahui;
Zhou, Chenhang;
Ying, Xiaowei;
Zhao, Jinhua;
Jin, Xinchun

Publication type:

Article

HNF4G accelerates glioma progression by facilitating NRP1 transcription.

Published in:

Oncology Letters, 2023, v. 25, n. 3, p. N.PAG, doi. 10.3892/ol.2023.13688

By:

Che, Hongmin;
Zheng, Qi;
Liao, Zijun;
Zhang, Lu

Publication type:

Article

A comprehensive analysis of the expression, epigenetic and genetic changes of HNF1B and ECI2 in 122 cases of high-grade serous ovarian carcinoma.

Published in:

Oncology Letters, 2021, v. 21, n. 3, p. N.PAG, doi. 10.3892/ol.2021.12446

By:

Němejcová, Kristýna;
Bártů, Michaela;
Hojný, Jan;
Hájková, Nikola;
Michálková, Romana;
Krkavcová, Eva;
Stružinská, Ivana;
Bui, Hiep Quang;
Dundr, Pavel;
Cibula, David;
Jirsová, Kateřina

Publication type:

Article

Overexpression of Rhophilin Rho GTPase-binding protein 2 promotes hepatocellular carcinoma.

Published in:

Oncology Letters, 2020, v. 20, n. 6, p. N.PAG, doi. 10.3892/ol.2020.12245

By:

Yuan, Bo;
Bo, Wentao;
Feng, Xielin;
Hu, Yong;
Zeng, Jiawei

Publication type:

Article

miR-375-3p inhibits the progression of laryngeal squamous cell carcinoma by targeting hepatocyte nuclear factor-1β.

Published in:

Oncology Letters, 2020, v. 20, n. 4, p. N.PAG, doi. 10.3892/ol.2020.11941

By:

Chang, Kunpeng;
Wei, Zhenxing;
Cao, Hua

Publication type:

Article

Checkpoint kinase 1 inhibitors as targeted molecular agents for clear cell carcinoma of the ovary (Review).

Published in:

Oncology Letters, 2015, v. 10, n. 2, p. 571, doi. 10.3892/ol.2015.3268

By:

HIROSHI KOBAYASHI;
HIROSHI SHIGETOMI;
CHIHARU YOSHIMOTO

Publication type:

Article

Toward an understanding of the pathophysiology of clear cell carcinoma of the ovary (Review).

Published in:

Oncology Letters, 2013, v. 6, n. 5, p. 1163, doi. 10.3892/ol.2013.1550

By:

CHIHARU UEKURI;
HIROSHI SHIGETOMI;
SUMIRE ONO;
YOSHIKAZU SASAKI;
MIYUKI MATSUURA;
HIROSHI KOBAYASHI

Publication type:

Article

Transcriptional networks in the human epididymis.

Published in:

Andrology, 2019, v. 7, n. 5, p. 741, doi. 10.1111/andr.12629

By:

Browne, J. A.;
Leir, S‐H.;
Yin, S.;
Harris, A.

Publication type:

Article

Human Hepatocyte Nuclear Factors (HNF1 and LXRb) Regulate CYP7A1 in HIV-Infected Black South African Women with Gallstone Disease: A Preliminary Study.

Published in:

Life (2075-1729), 2023, v. 13, n. 2, p. 273, doi. 10.3390/life13020273

By:

Kinoo, Suman Mewa;
Naidoo, Pragalathan;
Singh, Bhugwan;
Chuturgoon, Anil;
Nagiah, Savania

Publication type:

Article

Regulation of Hepatocyte Nuclear Factor 4α Attenuated Lipotoxicity but Increased Bile Acid Toxicity in Non-Alcoholic Fatty Liver Disease.

Published in:

Life (2075-1729), 2022, v. 12, n. 11, p. 1682, doi. 10.3390/life12111682

By:

Roh, Yoon Jin;
Kim, Yun;
Lee, Jae Sun;
Oh, Ju Hee;
Lee, Seung Min;
Yoon, Eileen Laurel;
Lee, Sung Ryol;
Jun, Dae Won

Publication type:

Article

Hepatocyte Growth Factor-Dependent Antiviral Activity of Activated cdc42-Associated Kinase 1 Against Hepatitis B Virus.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.800935

By:

Lee, Hye Won;
Choi, Yongwook;
Lee, Ah Ram;
Yoon, Cheol-Hee;
Kim, Kyun-Hwan;
Choi, Byeong-Sun;
Park, Yong Kwang

Publication type:

Article

An Atypical HNF4A Mutation Which Does Not Conform to the Classic Presentation of HNF4A-MODY.

Published in:

Case Reports in Endocrinology, 2018, p. 1, doi. 10.1155/2018/1560472

By:

Spiro, Andrew J.;
Vu, Katherine N.;
Warnock, Alicia Lynn

Publication type:

Article

Association of Agenesis of the Dorsal Pancreas With HNF1B Heterozygote Mutation: A Case Report.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.640006

By:

Guo, Mei;
Xu, Qinqin;
Yu, Xuefeng;
Yang, Qin;
Shao, Shiying

Publication type:

Article

HNF1A POU Domain Mutations Found in Japanese Liver Cancer Patients Cause Downregulation of HNF4A Promoter Activity with Possible Disruption in Transcription Networks.

Published in:

Genes, 2022, v. 13, n. 3, p. 413, doi. 10.3390/genes13030413

By:

Haque, Effi;
Teeli, Aamir Salam;
Winiarczyk, Dawid;
Taguchi, Masahiko;
Sakuraba, Shun;
Kono, Hidetoshi;
Leszczyński, Paweł;
Pierzchała, Mariusz;
Taniguchi, Hiroaki

Publication type:

Article

Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5' Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis.

Published in:

Genes, 2020, v. 11, n. 5, p. 486, doi. 10.3390/genes11050486

By:

Bolleyn, Jennifer;
Rombaut, Matthias;
Nair, Nisha;
Branson, Steven;
Heymans, Anja;
Chuah, Marinee;
VandenDriessche, Thierry;
Rogiers, Vera;
De Kock, Joery;
Vanhaecke, Tamara

Publication type:

Article

HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II.

Published in:

Genes, 2019, v. 10, n. 1, p. 21, doi. 10.3390/genes10010021

By:

DeLaForest, Ann;
Di Furio, Francesca;
Jing, Ran;
Ludwig-Kubinski, Amy;
Twaroski, Kirk;
Urick, Amanda;
Pulakanti, Kirthi;
Rao, Sridhar;
Duncan, Stephen A.

Publication type:

Article

Regulation of hepatic TRB3/Akt interaction induced by physical exercise and its effect on the hepatic glucose production in an insulin resistance state.

Published in:

Diabetology & Metabolic Syndrome, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13098-015-0064-x

By:

Marinho, Rodolfo;
Mekary, Rania A.;
Muñoz, Vitor Rosetto;
Gomes, Ricardo José;
Pauli, José Rodrigo;
Pereira de Moura, Leandro

Publication type:

Article

HNF1A-AS1 Regulates Cell Migration, Invasion and Glycolysis via Modulating miR-124/MYO6 in Colorectal Cancer Cells.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 1507, doi. 10.2147/OTT.S231249

By:

Guo, Xiong;
Zhang, Yang;
Liu, Ling;
Yang, Weiming;
Zhang, Qi

Publication type:

Article

Prognostic role of long non-coding RNA HNF1A-AS1 in Chinese cancer patients: a meta-analysis.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 5325, doi. 10.2147/OTT.S163575

By:

Zhuang, Chunbo;
Zheng, Lei;
Wang, Pei

Publication type:

Article

Incidence of HNF1A and GCK MODY Variants in a South African Population.

Published in:

Application of Clinical Genetics, 2020, v. 13, p. 209, doi. 10.2147/TACG.S281872

By:

Matsha, Tandi E;
Raghubeer, Shanel;
Tshivhase, Abegail M;
Davids, Saarah FG;
Hon, Gloudina M;
Bjørkhaug, Lise;
Erasmus, Rajiv T

Publication type:

Article

DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0214338

By:

Giantin, Mery;
Küblbeck, Jenni;
Zancanella, Vanessa;
Prantner, Viktoria;
Sansonetti, Fabiana;
Schoeniger, Axel;
Tolosi, Roberta;
Guerra, Giorgia;
Da Ros, Silvia;
Dacasto, Mauro;
Honkakoski, Paavo

Publication type:

Article

CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α) regulate expression of the human fructose-1,6-bisphosphatase 1 (FBP1) gene in human hepatocellular carcinoma HepG2 cells.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194252

By:

Wattanavanitchakorn, Siriluck;
Rojvirat, Pinnara;
Chavalit, Tanit;
MacDonald, Michael J.;
Jitrapakdee, Sarawut

Publication type:

Article

FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS.

Published in:

Nature Medicine, 2014, v. 20, n. 3, p. 272, doi. 10.1038/nm.3485

By:

Liu, Yawei;
Carlsson, Robert;
Comabella, Manuel;
Wang, JunYang;
Kosicki, Michael;
Carrion, Belinda;
Hasan, Maruf;
Wu, Xudong;
Montalban, Xavier;
Dziegiel, Morten Hanefeld;
Sellebjerg, Finn;
Sørensen, Per Soelberg;
Helin, Kristian;
Issazadeh-Navikas, Shohreh

Publication type:

Article

Clinicopathological heterogeneity in ovarian clear cell adenocarcinoma: a study on individual therapy practice.

Published in:

Medical Molecular Morphology, 2015, v. 48, n. 3, p. 146, doi. 10.1007/s00795-014-0090-z

By:

Matsuo, Yuji;
Tashiro, Hironori;
Yanai, Hiroyuki;
Moriya, Takuya;
Katabuchi, Hidetaka

Publication type:

Article

Expression profile analysis of the inflammatory response regulated by hepatocyte nuclear factor 4α.

Published in:

BMC Genomics, 2011, v. 12, p. 1, doi. 10.1186/1471-2164-12-128

By:

Wang, Zhongyan;
Bishop, Eric P;
Burke, Peter A

Publication type:

Article

Nuclear Receptor HNF4α Binding Sequences are Widespread in Alu Repeats.

Published in:: BMC Genomics, 2011, v. 12, n. Suppl 2, p. 560, doi. 10.1186/1471-2164-12-560
Publication type:: Article

microRNA-141 inhibits cell proliferation and invasion and promotes apoptosis by targeting hepatocyte nuclear factor-3beta in hepatocellular carcinoma cells.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-879

By:

Li Lin;
Hongwei Liang;
Yanbo Wang;
Xiaomao Yin;
Yanwei Hu;
Jinlan Huang;
Tingyu Ren;
Hui Xu;
Lei Zheng;
Xi Chen

Publication type:

Article

microRNA-141 inhibits cell proliferation and invasion and promotes apoptosis by targeting hepatocyte nuclear factor-3β in hepatocellular carcinoma cells.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-879

By:

Li Lin;
Hongwei Liang;
Yanbo Wang;
Xiaomao Yin;
Yanwei Hu;
Jinlan Huang;
Tingyu Ren;
Hui Xu;
Lei Zheng;
Xi Chen

Publication type:

Article

Conjunction of G-quadruplex and stem-loop in the 5′ untranslated region of mouse hepatocyte nuclear factor 4-alpha1 mediates strong inhibition of protein expression.

Published in:

Molecular & Cellular Biochemistry, 2018, v. 446, n. 1/2, p. 73, doi. 10.1007/s11010-018-3274-3

By:

Guo, Shangdong;
Lu, Hong

Publication type:

Article

Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 381, n. 1/2, p. 127, doi. 10.1007/s11010-013-1694-7

By:

Fang, Dian-liang;
Wan, Ying;
Shen, Wei;
Cao, Jie;
Sun, Zhong-xin;
Yu, Hui-hong;
Zhang, Qin;
Cheng, Wen-hui;
Chen, Juan;
Ning, Bo

Publication type:

Article

Role of HNF6 in liver homeostasis and pathophysiology.

Published in:

2025

By:

Tian, Miaomiao;
Gao, Weizhen;
Ma, Shujun;
Cao, Huiling;
Zhang, Yu;
An, Fuxiang;
Qi, Jianni;
Yang, Zhen

Publication type:

Literature Review

Mechanisms of ion transport regulation by HNF1β in the kidney: beyond transcriptional regulation of channels and transporters.

Published in:

Pflügers Archiv: European Journal of Physiology, 2022, v. 474, n. 8, p. 901, doi. 10.1007/s00424-022-02697-5

By:

Tholen, Lotte E.;
Hoenderop, Joost G. J.;
de Baaij, Jeroen H. F.

Publication type:

Article

Hepatocyte nuclear factor 6 inhibits the growth and metastasis of cholangiocarcinoma cells by regulating miR-122.

Published in:

Journal of Cancer Research & Clinical Oncology, 2016, v. 142, n. 5, p. 969, doi. 10.1007/s00432-016-2121-8

By:

Zhu, Huaqiang;
Mi, Yuetang;
Jiang, Xian;
Zhou, Xu;
Li, Rui;
Wei, Zheng;
Jiang, Hongchi;
Lu, Jun;
Sun, Xueying

Publication type:

Article

Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model.

Published in:

GeroScience, 2024, v. 46, n. 6, p. 5967, doi. 10.1007/s11357-024-01137-9

By:

Abudahab, Sara;
Kronfol, Mohamad M.;
Dozmorov, Mikhail G.;
Campbell, Thomas;
Jahr, Fay M.;
Nguyen, Jasmine;
AlAzzeh, Ola;
Al Saeedy, Dalia Y.;
Victor, Ashley;
Lee, Sera;
Malay, Shravani;
Lapato, Dana M.;
Halquist, Matthew S.;
McRae, MaryPeace;
Deshpande, Laxmikant S.;
Slattum, Patricia W.;
Price, Elvin T.;
McClay, Joseph L.

Publication type:

Article

亚砷酸钠对人正常肝细胞脂质代谢及因子调控的作用.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2025, v. 29, n. 23, p. 4956, doi. 10.12307/2025.509

By:

田侦丽;
张小旭;
方兴艳;
谢婷婷

Publication type:

Article

Cofunctional Subpathways Were Regulated by Transcription Factor with Common Motif, Common Family, or Common Tissue.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/780357

By:

Su, Fei;
Shang, Desi;
Xu, Yanjun;
Feng, Li;
Yang, Haixiu;
Liu, Baoquan;
Su, Shengyang;
Chen, Lina;
Li, Xia

Publication type:

Article

N-Glycomic and Transcriptomic Changes Associated with CDX1 mRNA Expression in Colorectal Cancer Cell Lines.

Published in:

Cells (2073-4409), 2019, v. 8, n. 3, p. 273, doi. 10.3390/cells8030273

By:

Holst, Stephanie;
Wilding, Jennifer L.;
Koprowska, Kamila;
Rombouts, Yoann;
Wuhrer, Manfred

Publication type:

Article

ONECUT1 variants beyond type 1 and type 2 diabetes: exploring clinical diversity and epigenetic associations in Arab cohorts.

Published in:

Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1254833

By:

Dashti, Mohammed;
Nizam, Rasheeba;
John, Sumi Elsa;
Melhem, Motasem;
Channanath, Arshad;
Alkandari, Hessa;
Thanaraj, Thangavel Alphonse;
Al-Mulla, Fahd

Publication type:

Article

ONECUT1 variants beyond type 1 and type 2 diabetes: exploring clinical diversity and epigenetic associations in Arab cohorts.

Published in:

Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1254833

By:

Dashti, Mohammed;
Nizam, Rasheeba;
John, Sumi Elsa;
Melhem, Motasem;
Channanath, Arshad;
Alkandari, Hessa;
Thanaraj, Thangavel Alphonse;
Al-Mulla, Fahd

Publication type:

Article

Dysregulation of HNF1B/Clusterin axis enhances disease progression in a highly aggressive subset of pancreatic cancer patients.

Published in:

Carcinogenesis, 2022, v. 43, n. 12, p. 1198, doi. 10.1093/carcin/bgac092

By:

Yang, Shouhui;
Tang, Wei;
Azizian, Azadeh;
Gaedcke, Jochen;
Ströbel, Philipp;
Wang, Limin;
Cawley, Helen;
Ohara, Yuuki;
Valenzuela, Paloma;
Zhang, Lin;
Lal, Trisha;
Sinha, Sanju;
Rupin, Eythan;
Hanna, Nader;
Ghadimi, B Michael;
Hussain, S Perwez

Publication type:

Article

Identification of biomarkers for the diagnosis and targets for therapy in patients with clear cell ovarian cancer: a systematic literature review.

Published in:

Carcinogenesis, 2022, v. 43, n. 3, p. 183, doi. 10.1093/carcin/bgac012

By:

Butler, Holly;
Saulat, Omar;
Guinn, Barbara-ann

Publication type:

Article

microRNA-320b suppresses HNF4G and IGF2BP2 expression to inhibit angiogenesis and tumor growth of lung cancer.

Published in:

Carcinogenesis, 2021, v. 42, n. 5, p. 762, doi. 10.1093/carcin/bgab023

By:

Ma, Yu-Shui;
Shi, Bo-Wen;
Guo, Jun-Hong;
Liu, Ji-Bin;
Yang, Xiao-Li;
Xin, Rui;
Shi, Yi;
Zhang, Dan-Dan;
Lu, Gai-Xia;
Jia, Cheng-You;
Wang, Hui-Min;
Wang, Pei-Yao;
Yang, Hui-Qiong;
Zhang, Jia-Jia;
Wu, Wei;
Cao, Ping-Sheng;
Yin, Yu-Zhen;
Gu, Li-Peng;
Tian, Lin-Lin;
Lv, Zhong-Wei

Publication type:

Article

Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A.

Published in:

Carcinogenesis, 2014, v. 35, n. 12, p. 2670, doi. 10.1093/carcin/bgu193

By:

Hoskins, Jason W.;
Jia, Jinping;
Flandez, Marta;
Parikh, Hemang;
Xiao, Wenming;
Collins, Irene;
Emmanuel, Mickey A.;
Ibrahim, Abdisamad;
Powell, John;
Zhang, Lizhi;
Malats, Nuria;
Bamlet, William R.;
Petersen, Gloria M.;
Real, Francisco X.;
Amundadottir, Laufey T.

Publication type:

Article

FOXA2 suppresses the metastasis of hepatocellular carcinoma partially through matrix metalloproteinase-9 inhibition.

Published in:

Carcinogenesis, 2014, v. 35, n. 11, p. 2576, doi. 10.1093/carcin/bgu180

By:

Wang, Jian;
Zhu, Chang-Peng;
Hu, Ping-Fang;
Qian, Hui;
Ning, Bei-Fang;
Zhang, Qing;
Chen, Fei;
Liu, Jiao;
Shi, Bin;
Zhang, Xin;
Xie, Wei-Fen

Publication type:

Article

Estrogen receptor α or β loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFβ and HNF3β signaling.

Published in:

Carcinogenesis, 2014, v. 35, n. 1, p. 96, doi. 10.1093/carcin/bgt323

By:

Hasson, Rian M.;
Briggs, Alexandra;
Carothers, Adelaide M.;
Davids, Jennifer S.;
Wang, Jiping;
Javid, Sara H.;
Cho, Nancy L.;
Bertagnolli, Monica M.

Publication type:

Article

The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27934-w

By:

Girard, Romain;
Tremblay, Sarah;
Noll, Christophe;
St-Jean, Stéphanie;
Jones, Christine;
Gélinas, Yves;
Maloum-Rami, Faïza;
Perreault, Nathalie;
Laplante, Mathieu;
Carpentier, André C.;
Boudreau, François

Publication type:

Article