Works matching DE "CHYMASES"

Results: 63

Dual inhibition of cathepsin G and chymase reduces myocyte death and improves cardiac remodeling after myocardial ischemia reperfusion injury.

Published in:

Basic Research in Cardiology, 2017, v. 112, n. 6, p. 1, doi. 10.1007/s00395-017-0652-z

By:

Hooshdaran, Bahman;
Kolpakov, Mikhail;
Guo, Xinji;
Miller, Sonni;
Wang, Tao;
Tilley, Douglas;
Rafiq, Khadija;
Sabri, Abdelkarim

Publication type:

Article

Involvement of premacular mast cells in the pathogenesis of macular diseases.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211438

By:

Sato, Takaki;
Morishita, Seita;
Horie, Taeko;
Fukumoto, Masanori;
Kida, Teruyo;
Oku, Hidehiro;
Nakamura, Kimitoshi;
Takai, Shinji;
Jin, Denan;
Ikeda, Tsunehiko

Publication type:

Article

Comparison of a chymase inhibitor and hyaluronic acid/carboxymethylcellulose (Seprafilm) in a novel peritoneal adhesion model in rats.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0211391

By:

Ozeki, Maiko;
Jin, Denan;
Miyaoka, Yuta;
Masubuchi, Shinsuke;
Hirokawa, Fumitoshi;
Hayashi, Michihiro;
Takai, Shinji;
Uchiyama, Kazuhisa

Publication type:

Article

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0207826

By:

Thorpe, Michael;
Fu, Zhirong;
Albat, Emanuelle;
Akula, Srinivas;
de Garavilla, Lawrence;
Kervinen, Jukka;
Hellman, Lars

Publication type:

Article

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0195077

By:

Thorpe, Michael;
Fu, Zhirong;
Chahal, Gurdeep;
Akula, Srinivas;
Kervinen, Jukka;
de Garavilla, Lawrence;
Hellman, Lars

Publication type:

Article

Systemic mastocytosis presenting as cardiac tamponade with CD25<sup>+</sup> pericardial mast cells.

Published in:

Clinical Case Reports, 2016, v. 4, n. 3, p. 279, doi. 10.1002/ccr3.505

By:

Sukrithan, Vineeth K.;
Salamon, Jason N.;
Berulava, Giorgi;
Sibinga, Nicholas E.;
Verma, Amit

Publication type:

Article

Pharmacokinetics, Safety, and Tolerability of the Novel Chymase Inhibitor BAY 1142524 in Healthy Male Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2019, v. 8, n. 4, p. 467, doi. 10.1002/cpdd.579

By:

Kanefendt, Friederike;
Thuß, Uwe;
Becka, Michael;
Boxnick, Stefanie;
Berse, Matthias;
Schultz, Armin;
Otto, Christiane

Publication type:

Article

Altered Immunohistochemical Expression of Mast Cell Tryptase and Chymase in the Pathogenesis of Oral Submucous Fibrosis and Malignant Transformation of the Overlying Epithelium.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098719

By:

Yadav, Archana;
Desai, Rajiv S.;
Bhuta, Bansari A.;
Singh, Jatinder S.;
Mehta, Reema;
Nehete, Akash P.

Publication type:

Article

Association of the Common Genetic Polymorphisms and Haplotypes of the Chymase Gene with Left Ventricular Mass in Male Patients with Symptomatic Aortic Stenosis.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096306

By:

Orlowska-Baranowska, Ewa;
Gora, Jaroslaw;
Baranowski, Rafal;
Stoklosa, Patrycjusz;
Gadomska vel Betka, Lucja;
Pedzich-Placha, Ewa;
Milkowska, Malogrzata;
Koblowska, Marta K.;
Hryniewiecki, Tomasz;
Gaciong, Zbigniew;
Placha, Grzegorz

Publication type:

Article

Chymase Mediates Injury and Mitochondrial Damage in Cardiomyocytes during Acute Ischemia/Reperfusion in the Dog.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094732

By:

Zheng, Junying;
Wei, Chih-Chang;
Hase, Naoki;
Shi, Ke;
Killingsworth, Cheryl R.;
Litovsky, Silvio H.;
Powell, Pamela C.;
Kobayashi, Tsunefumi;
Ferrario, Carlos M.;
Rab, Andras;
Aban, Inmaculada;
Collawn, James F.;
Dell'Italia, Louis J.

Publication type:

Article

Generation of a New Congenic Mouse Strain with Enhanced Chymase Expression in Mast Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084340

By:

Jin, Xi;
Zhao, Wanke;
Shi, Kaiyao;
Ho, Wanting T.;
Zhao, Zhizhuang J.

Publication type:

Article

Mutations in Arg143 and Lys192 of the Human Mast Cell Chymase Markedly Affect the Activity of Five Potent Human Chymase Inhibitors.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065988

By:

Ahooghalandari, Parvin;
Hanke, Nina;
Thorpe, Michael;
Witte, Andreas;
Messinger, Josef;
Hellman, Lars

Publication type:

Article

A Combination of Receptor-Based Pharmacophore Modeling & QM Techniques for Identification of Human Chymase Inhibitors.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0063030

By:

Arooj, Mahreen;
Sakkiah, Sugunadevi;
Kim, Songmi;
Arulalapperumal, Venkatesh;
Lee, Keun Woo

Publication type:

Article

Molecular Modeling Study for Inhibition Mechanism of Human Chymase and Its Application in Inhibitor Design.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062740

By:

Arooj, Mahreen;
Kim, Songmi;
Sakkiah, Sugunadevi;
Cao, Guang Ping;
Lee, Yuno;
Lee, Keun Woo

Publication type:

Article

Increased Mast Cell Density and Airway Responses to Allergic and Non-Allergic Stimuli in a Sheep Model of Chronic Asthma.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037161

By:

Van der Velden, Joanne;
Barker, Donna;
Barcham, Garry;
Koumoundouros, Emmanuel;
Snibson, Kenneth

Publication type:

Article

Computational Studies of Novel Chymase Inhibitors Against Cardiovascular and Allergic Diseases: Mechanism and Inhibition.

Published in:

Chemical Biology & Drug Design, 2012, v. 80, n. 6, p. 862, doi. 10.1111/cbdd.12006

By:

Arooj, Mahreen;
Thangapandian, Sundarapandian;
John, Shalini;
Hwang, Swan;
Park, Jong K.;
Lee, Keun W.

Publication type:

Article

Combination of Chymostatin and Aliskiren attenuates ER stress induced by lipid overload in kidney tubular cells.

Published in:

Lipids in Health & Disease, 2018, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12944-018-0818-1

By:

Qiu, Miaojuan;
Li, Suchun;
Jin, Lizi;
Feng, Pinning;
Kong, Yonglun;
Zhao, Xiaoduo;
Lin, Yu;
Xu, Yunyun;
Li, Chunling;
Wang, Weidong

Publication type:

Article

Chymase Inhibition and Cardiovascular Protection.

Published in:

Cardiovascular Drugs & Therapy, 2013, v. 27, n. 2, p. 139, doi. 10.1007/s10557-013-6450-4

By:

Tojo, Hideaki;
Urata, Hidenori

Publication type:

Article

In focus in HCB.

Published in:

2017

By:

Taatjes, Douglas;
Roth, Jürgen

Publication type:

Editorial

Mast cell chymase promotes hypertrophic scar fibroblast proliferation and collagen synthesis by activating TGF-β1/Smads signaling pathway.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 5, p. 4438, doi. 10.3892/etm.2017.5082

By:

HONGMING CHEN;
YANWEN XU;
GUANBIN YANG;
QIANQIAN ZHANG;
XUN HUANG;
LIMING YU;
XIANGLIN DONG

Publication type:

Article

High concentrations of mast cell chymase facilitate the transduction of the transforming growth factor-β1/Smads signaling pathway in skin fibroblasts.

Published in:

Experimental & Therapeutic Medicine, 2015, v. 9, n. 3, p. 955, doi. 10.3892/etm.2015.2216

By:

XIANGLIN DONG;
CHUANSHAN ZHANG;
SHAOLIN MA;
HAO WEN

Publication type:

Article

Increased expression of chymase in inflammatory polyps in elderly patients with functional bowel disorder.

Published in:

Experimental & Therapeutic Medicine, 2014, v. 7, n. 2, p. 371, doi. 10.3892/etm.2013.1444

By:

JIAN-MING RONG;
HONG-ZAN JI;
XIAO-WEI WU;
QUAN SUN;
MEI-XIA GUO;
XIAO-BING XU;
FANG-YU WANG

Publication type:

Article

Inflammatory cell patterns in the nasal mucosa of patients with idiopathic rhinitis.

Published in:

American Journal of Rhinology & Allergy, 2012, v. 26, n. 2, p. 55, doi. 10.2500/ajra.2012.26.3725

By:

Çomoğlu, Şenol;
Keles, Nesil;
Değer, Kemal

Publication type:

Article

Predomination of IL-17-producing tryptase-positive/chymase-positive mast cells in azoospermic chronic testicular inflammation.

Published in:

Andrologia, 2016, v. 48, n. 6, p. 617, doi. 10.1111/and.12487

By:

Chen, S.‐J.;
Duan, Y.‐G.;
Haidl, G.;
Allam, J.‐P.

Publication type:

Article

Comparación de las concentraciones séricas maternas de quimasa en pacientes con y sin preeclampsia.

Published in:

Ginecología y Obstetricia de México, 2016, v. 84, n. 6, p. 354

By:

Lara-Ávila, L.;
Herrera-Salazar, A.;
Morgan-Ortiz, F.;
Medina-Bastidas, D.;
Arámbula-Meráz, E.;
Osuna-Ramírez, I.

Publication type:

Article

Increased Bone Mass in Female Mice Lacking Mast Cell Chymase.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167964

By:

Lind, Thomas;
Gustafson, Ann-Marie;
Calounova, Gabriela;
Hu, Lijuan;
Rasmusson, Annica;
Jonsson, Kenneth B.;
Wernersson, Sara;
Åbrink, Magnus;
Andersson, Göran;
Larsson, Sune;
Melhus, Håkan;
Pejler, Gunnar

Publication type:

Article

Mast cell chymase protects against renal fibrosis in murine unilateral ureteral obstruction.

Published in:

Kidney International, 2013, v. 84, n. 2, p. 317, doi. 10.1038/ki.2013.98

By:

Beghdadi, Walid;
Madjene, Lydia C;
Claver, Julien;
Pejler, Gunnar;
Beaudoin, Lucie;
Lehuen, Agnès;
Daugas, Eric;
Blank, Ulrich

Publication type:

Article

Synthesis, Biological Evaluation of SPF-32629A-Based 2- and 4-Pyridone Analogs as Chymase Inhibitors.

Published in:

Bulletin of the Korean Chemical Society, 2014, v. 35, n. 8, p. 2547, doi. 10.5012/bkcs.2014.35.8.2547

By:

Xiang Fei;
Yue Yuan;
Young-Mi Lee;
Kwang Won Jeong;
Seung-Yong Seo

Publication type:

Article

The relationship between breast cancer molecular subtypes and mast cell populations in tumor microenvironment.

Published in:

2017

By:

Glajcar, Anna;
Szpor, Joanna;
Pacek, Agnieszka;
Tyrak, Katarzyna;
Chan, Florence;
Streb, Joanna;
Hodorowicz-Zaniewska, Diana;
Okoń, Krzysztof;
Tyrak, Katarzyna Ewa;
Okoń, Krzysztof

Publication type:

journal article

Complement C3 is expressed by mast cells in cutaneous vasculitis and is degraded by chymase.

Published in:

Archives of Dermatological Research, 2016, v. 308, n. 8, p. 575, doi. 10.1007/s00403-016-1677-0

By:

Lipitsä, Tiina;
Naukkarinen, Anita;
Laitala, Joel;
Harvima, Ilkka

Publication type:

Article

Mast cell tryptase and chymase in the progress of cutaneous vasculitis.

Published in:

Archives of Dermatological Research, 2015, v. 307, n. 10, p. 917, doi. 10.1007/s00403-015-1607-6

By:

Lipitsä, Tiina;
Naukkarinen, Anita;
Harvima, Ilkka

Publication type:

Article

Serum chymase levels correlate with severe dengue warning signs and clinical fluid accumulation in hospitalized pediatric patients.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68844-z

By:

Rathore, Abhay P. S.;
Senanayake, Manouri;
Athapathu, Arjuna Salinda;
Gunasena, Sunethra;
Karunaratna, Irantha;
Leong, Wei Yee;
Lim, Ting;
Mantri, Chinmay Kumar;
Wilder-Smith, Annelies;
St. John, Ashley L.

Publication type:

Article

Searching for Chymase Inhibitors among Chamomile Compounds Using a Computational-Based Approach.

Published in:

Biomolecules (2218-273X), 2019, v. 9, n. 1, p. 5, doi. 10.3390/biom9010005

By:

Dubey, Amit;
Dotolo, Serena;
Ramteke, Pramod W.;
Facchiano, Angelo;
Marabotti, Anna

Publication type:

Article

Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4-associated oxidative stress in diabetic hamsters.

Published in:

Journal of Diabetes Investigation, 2012, v. 3, n. 4, p. 354, doi. 10.1111/j.2040-1124.2012.00202.x

By:

Maeda, Yasutaka;
Inoguchi, Toyoshi;
Takei, Ryoko;
Hendarto, Hari;
Ide, Makoto;
Inoue, Tomoaki;
Kobayashi, Kunihisa;
Urata, Hidenori;
Nishiyama, Akira;
Takayanagi, Ryoichi

Publication type:

Article

ROLE OF MAST CELL IN ORAL PATHOLOGY.

Published in:

Oral & Maxillofacial Pathology Journal, 2013, v. 4, n. 1, p. 320

By:

Kheur, Supriya;
Patekar, Deepali;
Bagul, Neeta;
Kulkarni, Meena;
Routray, Samapika;
Dhas, Varsha

Publication type:

Article

Improvement of cardiovascular remodelling by chymase inhibitor.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2016, v. 43, n. 4, p. 387, doi. 10.1111/1440-1681.12549

By:

Takai, Shinji;
Jin, Denan

Publication type:

Article

Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease.

Published in:

Pulmonary Circulation, 2014, v. 4, n. 1, p. 128, doi. 10.1086/675642

By:

Kosanovic, Djuro;
Kumar Dahal, Bhola;
Peters, Dorothea Maren;
Seimetz, Michael;
Wygrecka, Malgorzata;
Hoffmann, Katrin;
Antel, Jochen;
Reiss, Irwin;
Ardeschir Ghofrani, Hossein;
Weissmann, Norbert;
Grimminger, Friedrich;
Seeger, Werner;
Schermuly, Ralph Theo

Publication type:

Article

Chymase inhibition protects diabetic rats from renal lesions.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 1, p. 121, doi. 10.3892/mmr.2016.5234

By:

MEI ZHANG;
WEN HUANG;
JING BAI;
XIAODONG NIE;
WEN WANG

Publication type:

Article

Identification of sites in apolipoprotein A-I susceptible to chymase and carboxypeptidase A digestion.

Published in:

Bioscience Reports, 2013, v. 33, n. 1, p. 49, doi. 10.1042/BSR20120094

By:

USAMI, Yoko;
KOBAYASHI, Yukihiro;
KAMEDA, Takahiro;
MIYAZAKI, Akari;
MATSUDA, Kazuyuki;
SUGANO, Mitsutoshi;
KAWASAKI, Kenji;
KURIHARA, Yuriko;
KASAMA, Takeshi;
TOZUKA, Minoru

Publication type:

Article

44. Jahrestagung der Österreichischen Diabetes Gesellschaft. "Chancen und Risiken für Menschen mit Diabetes".

Published in:: Wiener Klinische Wochenschrift, 2016, v. 128, p. 395, doi. 10.1007/s00508-016-1101-y
Publication type:: Article

Mast cells reside in myometrium and cervix, but are dispensable in mice for successful pregnancy and labor.

Published in:

Immunology & Cell Biology, 2012, v. 90, n. 3, p. 321, doi. 10.1038/icb.2011.40

By:

Menzies, Fiona M;
Higgins, Claire A;
Shepherd, Malcolm C;
Nibbs, Robert JB;
Nelson, Scott M

Publication type:

Article

Role of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human Data.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0162644

By:

Sansoè, Giovanni;
Aragno, Manuela;
Mastrocola, Raffaella;
Mengozzi, Giulio;
Novo, Erica;
Parola, Maurizio

Publication type:

Article

Correction: Granule Associated Serine Proteases of Hematopoietic Cells – An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145592

By:

Akula, Srinivas;
Thorpe, Michael;
Boinapally, Vamsi;
Hellman, Lars

Publication type:

Article

Granule Associated Serine Proteases of Hematopoietic Cells – An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

Published in:

PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0143091

By:

Akula, Srinivas;
Thorpe, Michael;
Boinapally, Vamsi;
Hellman, Lars

Publication type:

Article

Chymase Inhibitor as a Novel Therapeutic Agent for Non-alcoholic Steatohepatitis.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00144

By:

Takai, Shinji;
Jin, Denan

Publication type:

Article

Airway responsiveness to mannitol in asthma is associated with chymase-positive mast cells and eosinophilic airway inflammation.

Published in:

Clinical & Experimental Allergy, 2016, v. 46, n. 2, p. 288, doi. 10.1111/cea.12609

By:

Sverrild, A.;
Bergqvist, A.;
Baines, K. J.;
Porsbjerg, C.;
Andersson, C. K.;
Thomsen, S. F.;
Hoffmann, H. J.;
Gibson, P.;
Erjefält, J. S.;
Backer, V.

Publication type:

Article

In vitro and in vivo metabolism of a novel chymase inhibitor, SUN13834, and the predictability of human metabolism using mice with humanized liver.

Published in:

Xenobiotica, 2014, v. 44, n. 2, p. 154, doi. 10.3109/00498254.2013.865857

By:

Igawa, Yoshiyuki;
Fujitani, Tomomichi;
Shah, Bharti;
Oo, Charles;
Kanai, Yasushi

Publication type:

Article

Mast Cells: Key Contributors to Cardiac Fibrosis.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 1, p. 231, doi. 10.3390/ijms19010231

By:

Levick, Scott P.;
Widiapradja, Alexander

Publication type:

Article

Protease Expression Levels in Prostate Cancer Tissue Can Explain Prostate Cancer-Associated Seminal Biomarkers—An Explorative Concept Study.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 5, p. 976, doi. 10.3390/ijms18050976

By:

Neuhaus, Jochen;
Schiffer, Eric;
Mannello, Ferdinando;
Horn, Lars-Christian;
Ganzer, Roman;
Stolzenburg, Jens-Uwe

Publication type:

Article

Retinoic Acid Negatively Impacts Proliferation and MC<sub>TC</sub> Specific Attributes of Human Skin Derived Mast Cells, but Reinforces Allergic Stimulability.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 3, p. 525, doi. 10.3390/ijms18030525

By:

Babina, Magda;
Artuc, Metin;
Guhl, Sven;
Zuberbier, Torsten

Publication type:

Article