Works matching DE "CYCLIC nucleotide phosphodiesterases"

Results: 169

Radiation dosimetry of [<sup>11</sup>C]TZ1964B as determined by whole-body PET imaging of nonhuman primates.

Published in:

EJNMMI Research, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13550-025-01221-x

By:

Maiti, Baijayanta;
Goldman, Noah L.;
Hamdi, Mahdjoub;
Lenox-Krug, Jason;
Karimi, Morvarid;
Moerlein, Stephen M.;
Laforest, Richard;
Huang, Tianyu;
Tu, Zhude;
Perlmutter, Joel S.;
Norris, Scott A.

Publication type:

Article

Knockout of M-LP/Mpv17L, a newly identified atypical PDE, alleviates diabetic conditions in mice.

Published in:

Acta Diabetologica, 2024, v. 61, n. 10, p. 1327, doi. 10.1007/s00592-024-02337-7

By:

Iida, Reiko;
Ueki, Misuzu;
Yasuda, Toshihiro

Publication type:

Article

Knockout of M-LP/Mpv17L, a newly identified atypical PDE, induces physiological afferent cardiac hypertrophy in mice.

Published in:

Transgenic Research, 2023, v. 32, n. 6, p. 575, doi. 10.1007/s11248-023-00373-7

By:

Iida, Reiko;
Ueki, Misuzu;
Yasuda, Toshihiro

Publication type:

Article

Effects of Nitrosyl Iron Complexes with Thiocarbamide and Its Aliphatic Derivatives on Activities of Ca-ATPase of Sarcoplasmic Reticulum and cGMP Phosphodiesterase.

Published in:

Bulletin of Experimental Biology & Medicine, 2017, v. 163, n. 1, p. 54, doi. 10.1007/s10517-017-3736-8

By:

Tatyanenko, L.;
Shmatko, N.;
Sanina, N.;
Dobrokhotova, O.;
Pikhteleva, I.;
Kotel'nikov, A.;
Aldoshin, S.

Publication type:

Article

Multifunctional Cationic Peptide Fractions from Flaxseed Protein Hydrolysates.

Published in:

Plant Foods for Human Nutrition, 2012, v. 67, n. 1, p. 1, doi. 10.1007/s11130-012-0275-3

By:

Udenigwe, Chibuike;
Aluko, Rotimi

Publication type:

Article

Reverse fingerprinting, similarity searching by group fusion and fingerprint bit importance.

Published in:

Plant Foods for Human Nutrition, 2006, v. 61, n. 3, p. 311, doi. 10.1007/s11030-006-9039-z

By:

Williams, Chris

Publication type:

Article

Identification of Lithium-Regulated Genes in Cultured Lymphoblasts of Lithium Responsive Subjects with Bipolar Disorder.

Published in:

Neuropsychopharmacology, 2004, v. 29, n. 4, p. 799, doi. 10.1038/sj.npp.1300383

By:

Xiujun Sun, Jürgen;
L Trevor Young, Jürgen;
Jun-Feng Wang;
Grof, Paul;
Turecki, Gustavo;
Rouleau, Guy A.;
Alda, Martin

Publication type:

Article

A bioluminescent and homogeneous assay for monitoring GPCR-mediated cAMP modulation and PDE activity.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55038-0

By:

Mikheil, Dareen;
Larsen, Matthew A.;
Hsiao, Kevin;
Murray, Nathan H.;
Ugo, Tim;
Wang, Hui;
Goueli, Said A.

Publication type:

Article

Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice.

Published in:

Psychopharmacology, 2016, v. 233, n. 3, p. 447, doi. 10.1007/s00213-015-4129-1

By:

Lueptow, Lindsay;
Zhan, Chang-Guo;
O'Donnell, James

Publication type:

Article

Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity.

Published in:

Oncogene, 2015, v. 34, n. 12, p. 1499, doi. 10.1038/onc.2014.94

By:

Li, N;
Lee, K;
Xi, Y;
Zhu, B;
Gary, B D;
Ramírez-Alcántara, V;
Gurpinar, E;
Canzoneri, J C;
Fajardo, A;
Sigler, S;
Piazza, J T;
Chen, X;
Andrews, J;
Thomas, M;
Lu, W;
Li, Y;
Laan, D J;
Moyer, M P;
Russo, S;
Eberhardt, B T

Publication type:

Article

The G protein preference of orexin receptors is currently an unresolved issue.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38764-3

By:

Kukkonen, Jyrki P.

Publication type:

Article

Light up the COVID-19.

Published in:

Journal of Medical Signals & Sensors, 2022, v. 12, n. 4, p. 347, doi. 10.4103/jmss.jmss_135_21

By:

Neghab, Hoda;
Soheilifar, Mohammad;
Djavid, Gholamreza

Publication type:

Article

Functional Proteomic Profiling of Phosphodiesterases Using SeraFILE Separations Platform.

Published in:

International Journal of Proteomics, 2012, p. 1, doi. 10.1155/2012/515372

By:

Oka, Amita R.;
Kuruc, Matthew P.;
Gujarathi, Ketan M.;
Roy, Swapan

Publication type:

Article

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages.

Published in:

PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008447

By:

Munday, Jane C.;
Kunz, Stefan;
Kalejaiye, Titilola D.;
Siderius, Marco;
Schroeder, Susanne;
Paape, Daniel;
Alghamdi, Ali H.;
Abbasi, Zainab;
Huang, Sheng Xiang;
Donachie, Anne-Marie;
William, Samia;
Sabra, Abdel Nasser;
Sterk, Geert Jan;
Botros, Sanaa S.;
Brown, David G.;
Hoffman, Charles S.;
Leurs, Rob;
de Koning, Harry P.

Publication type:

Article

Effect of pranlukast on neonatal rats with periventricular leukomalacia.

Published in:

Chinese Journal of Contemporary Pediatrics, 2020, v. 22, n. 6, p. 656, doi. 10.7499/j.issn.1008-8830.1912139

By:

YE Xiao-Yan;
WANG Da-Yu;
XU Yan;
WANG Jun

Publication type:

Article

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets.

Published in:

Journal of Infectious Diseases, 2012, v. 206, n. 2, p. 229, doi. 10.1093/infdis/jir857

By:

de Koning, Harry P.;
Gould, Matthew K.;
Sterk, Geert Jan;
Tenor, Hermann;
Kunz, Stefan;
Luginbuehl, Edith;
Seebeck, Thomas

Publication type:

Article

Cardiac Cyclic Nucleotide Phosphodiesterases: Roles and Therapeutic Potential in Heart Failure.

Published in:

Cardiovascular Drugs & Therapy, 2020, v. 34, n. 3, p. 401, doi. 10.1007/s10557-020-06959-1

By:

Preedy, Michael E. J.

Publication type:

Article

The British Society for Cardiovascular Research Autumn 2019 Meeting Incorporating the Bernard and Joan Marshall Research Awards.

Published in:

2020

By:

Sinha, Sanjay;
Grieve, David J.

Publication type:

Editorial

Artificial intelligence utility for drug development: ChatGPT and beyond.

Published in:

2024

By:

Gurwitz, David;
Shomron, Noam

Publication type:

Product Review

Emerging Potential of the Phosphodiesterase (PDE) Inhibitor Ibudilast for Neurodegenerative Diseases: An Update on Preclinical and Clinical Evidence.

Published in:

Molecules, 2022, v. 27, n. 23, p. 8448, doi. 10.3390/molecules27238448

By:

Angelopoulou, Efthalia;
Pyrgelis, Efstratios-Stylianos;
Piperi, Christina

Publication type:

Article

Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine-Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography.

Published in:

Molecules, 2019, v. 24, n. 22, p. 4149, doi. 10.3390/molecules24224149

By:

Ritawidya, Rien;
Wenzel, Barbara;
Teodoro, Rodrigo;
Toussaint, Magali;
Kranz, Mathias;
Deuther-Conrad, Winnie;
Dukic-Stefanovic, Sladjana;
Ludwig, Friedrich-Alexander;
Scheunemann, Matthias;
Brust, Peter

Publication type:

Article

Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction.

Published in:

Cardiology, 2015, v. 132, n. 1, p. 45, doi. 10.1159/000430783

By:

Heijman, Jordi;
Heusch, Gerd;
Dobrev, Dobromir

Publication type:

Article

Sildenafil: A Review of its Use in Pulmonary Arterial Hypertension.

Published in:

Drugs, 2008, v. 68, n. 3, p. 383, doi. 10.2165/00003495-200868030-00009

By:

Croom, Katherine F;
Curran, Monique P

Publication type:

Article

Therapeutic Applications of Sildenafil Citrate in the Management of Paediatric Pulmonary Hypertension.

Published in:

Drugs, 2007, v. 67, n. 1, p. 57, doi. 10.2165/00003495-200767010-00005

By:

Leibovitch, Leah;
Matok, Ilan;
Paret, Gideon

Publication type:

Article

Role of PDE10A in vascular smooth muscle cell hyperplasia and pathological vascular remodelling.

Published in:

Cardiovascular Research, 2022, v. 118, n. 12, p. 2703, doi. 10.1093/cvr/cvab304

By:

Luo, Lingfeng;
Cai, Yujun;
Zhang, Yishuai;
Hsu, Chia G;
Korshunov, Vyacheslav A;
Long, Xiaochun;
Knight, Peter A;
Berk, Bradford C;
Yan, Chen

Publication type:

Article

Scientists on the Spot: Phosphodiesterases and heart failure.

Published in:

Cardiovascular Research, 2021, v. 117, n. 2, p. e24, doi. 10.1093/cvr/cvaa235

By:

Meli, Albano C;
Fischmeister, Rodolphe

Publication type:

Article

β-adrenergic receptors in cardiac muscle: it takes two to tango.

Published in:

Cardiovascular Research, 2020, v. 116, n. 13, p. 2033, doi. 10.1093/cvr/cvaa183

By:

Niggli, Ernst

Publication type:

Article

Evolution of multiple phosphodiesterase isoforms in stickleback involved in cAMP signal transduction pathway.

Published in:

BMC Systems Biology, 2009, v. 3, p. 1, doi. 10.1186/1752-0509-3-23

By:

Sato, Yukuto;
Hashiguchi, Yasuyuki;
Nishida, Mutsumi

Publication type:

Article

The Antiplatelet and Antithrombotic Effects of PF-253, a Potent and Selective PDE5 Inhibitor, in the Rabbit Folts Model of Arterial Thrombosis.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1166

By:

McClanahan, Thomas Blanc;
Zhiwu Lin;
Liguo Chi;
Rapp, Steve;
MacInesss, Alan

Publication type:

Article

Distinct PDE4D splice variants regulate beta-adrenergic signaling in neonatal mouse cardiac myocytes.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A997, doi. 10.1096/fasebj.21.6.a997-b

By:

Richter, Wito;
Day, Peter;
Wang, Yvonne;
Bruss, Matthew;
Wang, Ping;
Kobilka, Brian;
Conti, Marco

Publication type:

Article

Integrating cAMP and phospholipid signaling: role of phosphodiesterase 3B.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796, doi. 10.1096/fasebj.21.6.a796

By:

Wilson, Lindsay S.;
Maurice, Donald H.

Publication type:

Article

Protein kinase A phosphorylation of human phosphodiesterase 3B stimulates enzyme activity, promotes 14-3-3 protein binding and inhibits phosphatase- catalyzed inactivation.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796

By:

Jimmo, Sandra Lynn;
Palmer, Dan;
Raymond, Dan;
Wilson, Lindsay;
Carter, Rhonda;
Maurice, Donald

Publication type:

Article

Vascular smooth muscle cell podosomes: dynamic actin-based structures coordinating pro and anti migratory effects of cAMP elevating agents.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796

By:

Carter, Rhonda L.;
Furmaniak-Kazmierczak, Emilia;
Farber, Alison;
Cote, Graham P.;
Maurice, Donald H.

Publication type:

Article

Phosphodiesterase Inhibition Decreases Vascular Endothelial Permeability Without Global Changes in cAMP: Potential Role of Phosphodiesterase/VE-Cadherin Signaling Complexes.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796

By:

Ovens, Jeffrey D.;
Maurice, Donald H.

Publication type:

Article

Caffeine Enhances ATP Release from Erythrocytes: Consequences for Peripheral Vascular Perfusion.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A479, doi. 10.1096/fasebj.21.5.a479-d

By:

Ellsworth, Mary L.;
Chrzaszcz, MaryAnn;
O'Keefe, Emily;
Achilleus, David;
Bowles, Elizabeth;
Sprague, Randy S.

Publication type:

Article

LIPID METABOLISM AND TRANSPORT II (588.1-588.15).

Published in:: 2005
Publication type:: Abstract

An evolutionary analysis of cAMP-specific Phosphodiesterase 4 alternative splicing.

Published in:

BMC Evolutionary Biology, 2010, v. 10, p. 247, doi. 10.1186/1471-2148-10-247

By:

Johnson, Keven R.;
Nicodemus-Johnson, Jessie;
S.^Danziger, Robert

Publication type:

Article

Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase.

Published in:

Nature, 2009, v. 459, n. 7249, p. 1015, doi. 10.1038/nature07966

By:

Barends, Thomas R. M.;
Hartmann, Elisabeth;
Griese, Julia J.;
Beitlich, Thorsten;
Kirienko, Natalia V.;
Ryjenkov, Dmitri A.;
Reinstein, Jochen;
Shoeman, Robert L.;
Gomelsky, Mark;
Schlichting, Ilme

Publication type:

Article

Folate responsiveness during growth and development of Dictyostelium: separate but related pathways control chemotaxis and gene regulation.

Published in:

Molecular Microbiology, 1994, v. 11, n. 2, p. 331, doi. 10.1111/j.1365-2958.1994.tb00313.x

By:

Blusch, Jürgen H.;
Nellen, Wolfgang

Publication type:

Article

Phosphodiesterase 10A in the Rat Pineal Gland: Localization, Daily and Seasonal Regulation of Expression and Influence on Signal Transduction.

Published in:

Neuroendocrinology, 2011, v. 94, n. 2, p. 113, doi. 10.1159/000327138

By:

Spiwoks-Becker, Isabella;
Wolloscheck, Tanja;
Rickes, Oliver;
Kelleher, Debra K.;
Rohleder, Nils;
Weyer, Veronika;
Spessert, Rainer

Publication type:

Article

Heterogeneous expression of long noncoding RNA RP11-109D20.2: Insights into regulatory gene expression roles in colon cancer.

Published in:

Iranian Journal of Basic Medical Sciences, 2025, v. 28, n. 5, p. 592, doi. 10.22038/ijbms.2025.81777.17688

By:

Chitgaran, Sara;
Mahmoudian, Reihaneh Alsadat;
Khatami, Seyed Saeed;
Nasrabadi, Fatemeh;
Soltani, Ehsan;
Razavi, Amirnader Emami;
Kamali, Fatemeh;
Bahrami, Ahmad Reza;
Matin, Maryam Moghaddam;
Farshchian, Moein

Publication type:

Article

Identification and Localization of the Cyclic Nucleotide Phosphodiesterase 10A in Bovine Testis and Mature Spermatozoa.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161035

By:

Goupil, Serge;
Maréchal, Loïze;
El Hajj, Hassan;
Tremblay, Marie-Ève;
Richard, François J.;
Leclerc, Pierre

Publication type:

Article

Phosphodiesterase 4D7 selectively regulates cAMP-mediated control of human arterial endothelial cell transcriptomic responses to fluid shear stress.

Published in:

Canadian Journal of Physiology & Pharmacology, 2021, v. 99, n. 2, p. 179, doi. 10.1139/cjpp-2020-0318

By:

Burke-Kleinman, Jonah;
Maurice, Donald H.

Publication type:

Article

Astragaloside IV relieves gestational diabetes mellitus in genetic mice through reducing hepatic gluconeogenesis.

Published in:

Canadian Journal of Physiology & Pharmacology, 2020, v. 98, n. 7, p. 466, doi. 10.1139/cjpp-2019-0548

By:

Zhang, Ruixue;
Xing, Baoheng;
Zhao, Jianyong;
Zhang, Xuelei;
Zhou, Ling;
Yang, Shuangyan;
Wang, Yong;
Yang, Fengzhen

Publication type:

Article

Repurposing Human PDE4 Inhibitors for Neglected Tropical Diseases. Evaluation of Analogs of the Human PDE4 Inhibitor GSK-256066 as Inhibitors of PDEB1 of Trypanosoma brucei.

Published in:

Chemical Biology & Drug Design, 2015, v. 85, n. 5, p. 549, doi. 10.1111/cbdd.12443

By:

Ochiana, Stefan O.;
Bland, Nicholas D.;
Settimo, Luca;
Campbell, Robert K.;
Pollastri, Michael P.

Publication type:

Article

The N-Terminal Domain of 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase Harbors a GTP/ATP Binding Site.

Published in:

Chemical Biology & Drug Design, 2007, v. 70, n. 6, p. 502, doi. 10.1111/j.1747-0285.2007.00592.x

By:

Stingo, Stefania;
Masullo, Mariorosario;
Polverini, Eugenia;
Laezza, Chiara;
Ruggiero, Immacolata;
Arcone, Rosaria;
Ruozi, Enrica;
Piaz, Fabrizio Dal;
Malfitano, Anna Maria;
D'Ursi, Anna Maria;
Bifulco, Maurizio

Publication type:

Article

Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies.

Published in:

Journal of Neurochemistry, 2025, v. 169, n. 1, p. 1, doi. 10.1111/jnc.16274

By:

Markusson, Sigurbjörn;
Raasakka, Arne;
Schröder, Marcel;
Sograte‐Idrissi, Shama;
Rahimi, Amir Mohammad;
Asadpour, Ommolbanin;
Körner, Henrike;
Lodygin, Dmitri;
Eichel‐Vogel, Maria A.;
Chowdhury, Risha;
Sutinen, Aleksi;
Muruganandam, Gopinath;
Iyer, Manasi;
Cooper, Madeline H.;
Weigel, Maya K.;
Ambiel, Nicholas;
Werner, Hauke B.;
Zuchero, J. Bradley;
Opazo, Felipe;
Kursula, Petri

Publication type:

Article

Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 253, doi. 10.1186/1742-2094-9-253

By:

Silva, Jharon;
Polesskaya, Oksana;
Knight, Walter;
Zheng, Johnny Ting;
Granger, Megan;
Lopez, Ten‚e;
Ontiveros, Fernando;
Changyong Feng;
Chen Yan;
Kasischke, Karl A.;
Dewhurst, Stephen

Publication type:

Article

Inhibitory effect of acetamide-45 on airway inflammation and phosphodiesterase 4 in allergic rats.

Published in:

Acta Pharmacologica Sinica, 2005, v. 26, n. 12, p. 1492, doi. 10.1111/j.1745-7254.2005.00227.x

By:

Kai Wang;
Hua-hao Shen;
Jun-chun, Chen;
Zhong Chen

Publication type:

Article

Preclinical Characterization of the Phosphodiesterase 10A PET Tracer [(11)C]MK-8193.

Published in:

2016

By:

Hostetler, Eric;
Fan, Hong;
Joshi, Aniket;
Zeng, Zhizhen;
Eng, Waisi;
Gantert, Liza;
Holahan, Marie;
Meng, Xianjun;
Miller, Patricia;
O'Malley, Stacey;
Purcell, Mona;
Riffel, Kerry;
Salinas, Cristian;
Williams, Mangay;
Ma, Bennett;
Buist, Nicole;
Smith, Sean;
Coleman, Paul;
Cox, Christopher;
Flores, Brock

Publication type:

journal article