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- Title
Coagulation disorders in pregnancy: acquired and inherited thrombophilias.
- Authors
Benedetto, Chiara; Marozio, Luca; Tavella, Anna Maria; Salton, Loredana; Grivon, Sara; Di Giampaolo, Francesca
- Abstract
Both acquired and inherited thrombophilias are associated with an increased risk of pregnancy-related venous thromboembolism (VTE) as well as with adverse pregnancy outcome. However, the extension of attributable risk for each thrombophilia and outcome is still a question of debate. Thrombophilias have been investigated in connection with VTE and pregnancy complications such as: recurrent and nonrecurrent early pregnancy loss, late fetal death, placental abruption, fetal growth restriction, and preeclampsia. This review discusses the evidence of association between thrombophilias and pregnancy outcome together with issues as to clinical management and preventive strategies.
- Subjects
BLOOD coagulation disorders in pregnancy; THROMBOSIS; PREGNANCY complications; FETAL death; PREECLAMPSIA
- Publication
Annals of the New York Academy of Sciences, 2010, Vol 1205, Issue 1, p106
- ISSN
0077-8923
- Publication type
Academic Journal
- DOI
10.1111/j.1749-6632.2010.05674.x