Title: eEF1A2 as a Putative Oncogene.
Authors: Lee, Mee‐Hyun; Surh, Young‐Joon
Abstract: The first evidence for the role of the protein elongation factor eEF1A2 in tumorigenesis was reported by Anand and colleagues who demonstrated that eEF1A2 is overexpressed in about 30% of ovarian tumors and some established ovarian cancer cells. This abnormal expression correlates with a poor prognosis. Since this discovery, there have been several reports suggesting eEF1A2 as a diagnostic marker in various cancers. This review highlights the oncogenic potential of eEF1A2.
Subjects: ONCOGENES; CANCER genes; CELLULAR pathology; ONCOLOGY; CANCER cells
Publication: Annals of the New York Academy of Sciences, 2009, Vol 1171, p87
ISSN: 0077-8923
Publication type: Academic Journal
DOI: 10.1111/j.1749-6632.2009.04909.x

eEF1A2 as a Putative Oncogene.

Lee, Mee‐Hyun; Surh, Young‐Joon