Works matching DE "CYCLIC nucleotide phosphodiesterases"

Results: 169

In vitro effects of PDE5 inhibitors sildenafil, vardenafil and tadalafil on isolated human ureteral smooth muscle: a basic research approach.

Published in:

Urological Research, 2007, v. 35, n. 1, p. 49, doi. 10.1007/s00240-006-0073-1

By:

Gratzke, Christian;
Ückert, Stefan;
Kedia, Giorgi;
Reich, Oliver;
Schlenker, Boris;
Seitz, Michael;
Becker, Armin J.;
Stief, Christian G.

Publication type:

Article

Conserved expression and functions of PDE4 in rodent and human heart.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 2, p. 249, doi. 10.1007/s00395-010-0138-8

By:

Richter, Wito;
Xie, Moses;
Scheitrum, Colleen;
Krall, Judith;
Movsesian, Matthew;
Conti, Marco

Publication type:

Article

The Endocrine Function of the Heart: Physiology and Involvements of Natriuretic Peptides and Cyclic Nucleotide Phosphodiesterases in Heart Failure.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1746, doi. 10.3390/jcm8101746

By:

Lugnier, Claire;
Meyer, Alain;
Charloux, Anne;
Andrès, Emmanuel;
Gény, Bernard;
Talha, Samy

Publication type:

Article

An improved DNA-based test for detection of the codon 616 mutation in the alpha cyclic GMP phosphodiesterase gene that causes progressive retinal atrophy in the Cardigan Welsh Corgi.

Published in:

Veterinary Ophthalmology, 2002, v. 5, n. 2, p. 103, doi. 10.1046/j.1463-5224.2002.00223.x

By:

Petersen-Jones, Simon M.;
Entz, David D.

Publication type:

Article

NCS 613, a Potent PDE4 Inhibitor, Displays Anti-Inflammatory and Anti-Proliferative Properties on A549 Lung Epithelial Cells and Human Lung Adenocarcinoma Explants.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01266

By:

Yougbare, Issaka;
Belemnaba, Lazare;
Morin, Caroline;
Abusnina, Abdurazzag;
Senouvo, Yannick F.;
Keravis, Thérèse;
Lugnier, Claire;
Rousseau, Eric

Publication type:

Article

Evaluation of Modulators of cAMP-Response in Terms of Their Impact on Cell Cycle and Mitochondrial Activity of Leishmania donovani.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00782

By:

Saha, Amrita;
Bhattacharjee, Anindita;
Vij, Amit;
Das, Pijush K.;
Bhattacharya, Arijit;
Biswas, Arunima

Publication type:

Article

Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity.

Published in:

Oncogene, 2015, v. 34, n. 12, p. 1499, doi. 10.1038/onc.2014.94

By:

Li, N;
Lee, K;
Xi, Y;
Zhu, B;
Gary, B D;
Ramírez-Alcántara, V;
Gurpinar, E;
Canzoneri, J C;
Fajardo, A;
Sigler, S;
Piazza, J T;
Chen, X;
Andrews, J;
Thomas, M;
Lu, W;
Li, Y;
Laan, D J;
Moyer, M P;
Russo, S;
Eberhardt, B T

Publication type:

Article

Sildenafil: A Review of its Use in Pulmonary Arterial Hypertension.

Published in:

Drugs, 2008, v. 68, n. 3, p. 383, doi. 10.2165/00003495-200868030-00009

By:

Croom, Katherine F;
Curran, Monique P

Publication type:

Article

Therapeutic Applications of Sildenafil Citrate in the Management of Paediatric Pulmonary Hypertension.

Published in:

Drugs, 2007, v. 67, n. 1, p. 57, doi. 10.2165/00003495-200767010-00005

By:

Leibovitch, Leah;
Matok, Ilan;
Paret, Gideon

Publication type:

Article

Functional Proteomic Profiling of Phosphodiesterases Using SeraFILE Separations Platform.

Published in:

International Journal of Proteomics, 2012, p. 1, doi. 10.1155/2012/515372

By:

Oka, Amita R.;
Kuruc, Matthew P.;
Gujarathi, Ketan M.;
Roy, Swapan

Publication type:

Article

Special Issue: "Enzymes and Enzyme Inhibitors—Applications in Medicine and Diagnosis 2.0".

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13422, doi. 10.3390/ijms252413422

By:

Geronikaki, Athina

Publication type:

Article

Radiosynthesis and biological evaluation of the new PDE10A radioligand [<sup>18</sup>F]AQ28A.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2017, v. 60, n. 1, p. 36, doi. 10.1002/jlcr.3471

By:

Wagner, Sally;
Teodoro, Rodrigo;
Deuther ‐ Conrad, Winnie;
Kranz, Mathias;
Scheunemann, Matthias;
Fischer, Steffen;
Wenzel, Barbara;
Egerland, Ute;
Hoefgen, Norbert;
Steinbach, Jörg;
Brust, Peter

Publication type:

Article

Decreasing Cyclic GMP Exerts Similar Positive Functional Effects on Cardiac Myocytes Regardless of Initial Level.

Published in:

Pharmacology, 2000, v. 61, n. 1, p. 51, doi. 10.1159/000028380

By:

Lin Yan;
Huang, Mark W.;
Scholz, Peter M.;
Weiss, Harvey R.

Publication type:

Article

Effect of polycaprolactone/carbon nanotube scaffold implantation along with liposomal ellagic acid in hippocampal synaptogenesis after spinal cord injury.

Published in:

Nanomedicine Journal, 2023, v. 10, n. 3, p. 197, doi. 10.22038/NMJ.2023.72151.1776

By:

Gholami, Arman Abroumand;
Gheybi, Fatemeh;
Molavi, Amir Mahdi;
Tahmasebi, Fatemeh;
Papi, Arash;
Babaloo, Hamideh

Publication type:

Article

An EPAC1/PDE1C-Signaling Axis Regulates Formation of Leading-Edge Protrusion in Polarized Human Arterial Vascular Smooth Muscle Cells.

Published in:

Cells (2073-4409), 2019, v. 8, n. 12, p. 1473, doi. 10.3390/cells8121473

By:

Brzezinska, Paulina;
Maurice, Donald H.

Publication type:

Article

The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!

Published in:

Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00185

By:

Tagoe, Daniel N. A.;
Kalejaiye, Titilola D.;
de Koning, Harry P.

Publication type:

Article

Phosphodiesterases in neurodegenerative disorders.

Published in:

IUBMB Life, 2012, v. 64, n. 12, p. 965, doi. 10.1002/iub.1104

By:

Bollen, Eva;
Prickaerts, Jos

Publication type:

Article

Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005680

By:

Long, Thavy;
Rojo-Arreola, Liliana;
Shi, Da;
El-Sakkary, Nelly;
Jarnagin, Kurt;
Rock, Fernando;
Meewan, Maliwan;
Jr.Rascón, Alberto A.;
Lin, Lin;
Cunningham, Katherine A.;
Lemieux, George A.;
Podust, Larissa;
Abagyan, Ruben;
Ashrafi, Kaveh;
McKerrow, James H.;
Caffrey, Conor R.

Publication type:

Article

Role of Ser102 and Ser104 as Regulators of cGMP Hydrolysis by PDE5A.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107627

By:

Carøe Nordgaard, Julie;
Kruse, Lars Schack;
Gammeltoft, Steen;
Kruuse, Christina Rostrup

Publication type:

Article

Mechanisms of Cyclic Nucleotide Phosphodiesterases in Modulating T Cell Responses in Murine Graft-versus-Host Disease.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058110

By:

Weber, Michael;
Lupp, Corinna;
Stein, Pamela;
Kreft, Andreas;
Bopp, Tobias;
Wehler, Thomas C.;
Schmitt, Edgar;
Schild, Hansjörg;
Radsak, Markus P.

Publication type:

Article

β-Adrenergic cAMP Signals Are Predominantly Regulated by Phosphodiesterase Type 4 in Cultured Adult Rat Aortic Smooth Muscle Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047826

By:

Kui Zhai;
Hubert, Fabien;
Nicolas, Valérie;
Guangju Ji;
Fischmeister, Rodolphe;
Leblais, Véronique

Publication type:

Article

Expression and Regulation of Cyclic Nucleotide Phosphodiesterases in Human and Rat Pancreatic Islets.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014191

By:

Heimann, Emilia;
Jones, Helena A.;
Resjö, Svante;
Manganiello, Vincent C.;
Stenson, Lena;
Degerman, Eva

Publication type:

Article

Determination of Sildenafil, Tadalafil, and Vardenafil in Tablets and Adulterated Herbal Products by ESI‐MS‐MS.

Published in:

Journal of Liquid Chromatography & Related Technologies, 2006, v. 29, n. 4, p. 591, doi. 10.1080/10826070500479393

By:

Abdel-Hamid, M.

Publication type:

Article

Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-α and interleukin-1β by human mononuclear cells.

Published in:

Immunology, 1991, v. 72, n. 1, p. 56

By:

Endres, S.;
Fülle, H.-J.;
Sinha, B.;
Stoll, D.;
Dinarello, C.A.;
Gerzer, R.;
Weber, P.C.

Publication type:

Article

Repurposing Human PDE4 Inhibitors for Neglected Tropical Diseases. Evaluation of Analogs of the Human PDE4 Inhibitor GSK-256066 as Inhibitors of PDEB1 of Trypanosoma brucei.

Published in:

Chemical Biology & Drug Design, 2015, v. 85, n. 5, p. 549, doi. 10.1111/cbdd.12443

By:

Ochiana, Stefan O.;
Bland, Nicholas D.;
Settimo, Luca;
Campbell, Robert K.;
Pollastri, Michael P.

Publication type:

Article

The N-Terminal Domain of 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase Harbors a GTP/ATP Binding Site.

Published in:

Chemical Biology & Drug Design, 2007, v. 70, n. 6, p. 502, doi. 10.1111/j.1747-0285.2007.00592.x

By:

Stingo, Stefania;
Masullo, Mariorosario;
Polverini, Eugenia;
Laezza, Chiara;
Ruggiero, Immacolata;
Arcone, Rosaria;
Ruozi, Enrica;
Piaz, Fabrizio Dal;
Malfitano, Anna Maria;
D'Ursi, Anna Maria;
Bifulco, Maurizio

Publication type:

Article

The Antiplatelet and Antithrombotic Effects of PF-253, a Potent and Selective PDE5 Inhibitor, in the Rabbit Folts Model of Arterial Thrombosis.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1166

By:

McClanahan, Thomas Blanc;
Zhiwu Lin;
Liguo Chi;
Rapp, Steve;
MacInesss, Alan

Publication type:

Article

Distinct PDE4D splice variants regulate beta-adrenergic signaling in neonatal mouse cardiac myocytes.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A997, doi. 10.1096/fasebj.21.6.a997-b

By:

Richter, Wito;
Day, Peter;
Wang, Yvonne;
Bruss, Matthew;
Wang, Ping;
Kobilka, Brian;
Conti, Marco

Publication type:

Article

Integrating cAMP and phospholipid signaling: role of phosphodiesterase 3B.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796, doi. 10.1096/fasebj.21.6.a796

By:

Wilson, Lindsay S.;
Maurice, Donald H.

Publication type:

Article

Protein kinase A phosphorylation of human phosphodiesterase 3B stimulates enzyme activity, promotes 14-3-3 protein binding and inhibits phosphatase- catalyzed inactivation.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796

By:

Jimmo, Sandra Lynn;
Palmer, Dan;
Raymond, Dan;
Wilson, Lindsay;
Carter, Rhonda;
Maurice, Donald

Publication type:

Article

Vascular smooth muscle cell podosomes: dynamic actin-based structures coordinating pro and anti migratory effects of cAMP elevating agents.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796

By:

Carter, Rhonda L.;
Furmaniak-Kazmierczak, Emilia;
Farber, Alison;
Cote, Graham P.;
Maurice, Donald H.

Publication type:

Article

Phosphodiesterase Inhibition Decreases Vascular Endothelial Permeability Without Global Changes in cAMP: Potential Role of Phosphodiesterase/VE-Cadherin Signaling Complexes.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A796

By:

Ovens, Jeffrey D.;
Maurice, Donald H.

Publication type:

Article

Caffeine Enhances ATP Release from Erythrocytes: Consequences for Peripheral Vascular Perfusion.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A479, doi. 10.1096/fasebj.21.5.a479-d

By:

Ellsworth, Mary L.;
Chrzaszcz, MaryAnn;
O'Keefe, Emily;
Achilleus, David;
Bowles, Elizabeth;
Sprague, Randy S.

Publication type:

Article

LIPID METABOLISM AND TRANSPORT II (588.1-588.15).

Published in:: 2005
Publication type:: Abstract

C[sub 2]-Ceramide Influences the Expression and Insulin-Mediated Regulation of Cyclic Nucleotide Phosphodiesterase 3B and Lipolysis in 3T3-L1 Adipocytes.

Published in:

Diabetes, 2002, v. 51, n. 3, p. 631, doi. 10.2337/diabetes.51.3.631

By:

Jie Mei;
Holst, Lena Stenson;
Landström, Tova Rahn;
Holm, Cecilia;
Brindley, David;
Manganiello, Vincent;
Degerman, Eva

Publication type:

Article

CGMP-Phosphodiesterase Activity Is Up-regulated in Response to Pressure Overload of Rat Ventricles.

Published in:

Bioscience, Biotechnology & Biochemistry, 2003, v. 67, n. 5, p. 973, doi. 10.1271/bbb.67.973

By:

Yanaka, Noriyuki;
Kurosawa, Yukie;
Minami, Kouichi;
Kawai, Eri;
Omori, Kenji

Publication type:

Article

Cardiac Cyclic Nucleotide Phosphodiesterases: Roles and Therapeutic Potential in Heart Failure.

Published in:

Cardiovascular Drugs & Therapy, 2020, v. 34, n. 3, p. 401, doi. 10.1007/s10557-020-06959-1

By:

Preedy, Michael E. J.

Publication type:

Article

The British Society for Cardiovascular Research Autumn 2019 Meeting Incorporating the Bernard and Joan Marshall Research Awards.

Published in:

2020

By:

Sinha, Sanjay;
Grieve, David J.

Publication type:

Editorial

Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction.

Published in:

Cardiology, 2015, v. 132, n. 1, p. 45, doi. 10.1159/000430783

By:

Heijman, Jordi;
Heusch, Gerd;
Dobrev, Dobromir

Publication type:

Article

Multifunctional Cationic Peptide Fractions from Flaxseed Protein Hydrolysates.

Published in:

Plant Foods for Human Nutrition, 2012, v. 67, n. 1, p. 1, doi. 10.1007/s11130-012-0275-3

By:

Udenigwe, Chibuike;
Aluko, Rotimi

Publication type:

Article

Reverse fingerprinting, similarity searching by group fusion and fingerprint bit importance.

Published in:

Plant Foods for Human Nutrition, 2006, v. 61, n. 3, p. 311, doi. 10.1007/s11030-006-9039-z

By:

Williams, Chris

Publication type:

Article

Diuretic effect of Xanthine derivatives: A Critical Review.

Published in:

International Journal of Pharmaceutical Research (09752366), 2022, v. 14, n. 4, p. 1, doi. 10.31838/ijpr/2022.14.04.003

By:

SHABNAMTHAKUR;
YADAV, RAKESH;
SHARMA, RUPALI;
CHAWLA, AMIT

Publication type:

Article

NG2 and NG2-positive cells delineate focal cerebral infarct demarcation in rats.

Published in:

Neuropathology, 2013, v. 33, n. 1, p. 30, doi. 10.1111/j.1440-1789.2012.01322.x

By:

Claus, Helene L.;
Walberer, Maureen;
Simard, Marie L.;
Emig, Beata;
Muesken, Sophia M.;
Rueger, Maria A.;
Fink, Gereon R.;
Schroeter, Michael

Publication type:

Article

Protein microarray analysis identifies cyclic nucleotide phosphodiesterase as an interactor of Nogo-A.

Published in:

Neuropathology, 2010, v. 30, n. 1, p. 7, doi. 10.1111/j.1440-1789.2009.01035.x

By:

Sumiyoshi, Kenta;
Obayashi, Shinya;
Tabunoki, Hiroko;
Arima, Kunimasa;
Satoh, Jun-ichi

Publication type:

Article

A bioluminescent and homogeneous assay for monitoring GPCR-mediated cAMP modulation and PDE activity.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55038-0

By:

Mikheil, Dareen;
Larsen, Matthew A.;
Hsiao, Kevin;
Murray, Nathan H.;
Ugo, Tim;
Wang, Hui;
Goueli, Said A.

Publication type:

Article

Cyclic GMP-mediated memory enhancement in the object recognition test by inhibitors of phosphodiesterase-2 in mice.

Published in:

Psychopharmacology, 2016, v. 233, n. 3, p. 447, doi. 10.1007/s00213-015-4129-1

By:

Lueptow, Lindsay;
Zhan, Chang-Guo;
O'Donnell, James

Publication type:

Article

Genetic variation in phosphodiesterase (PDE) 7B in chronic lymphocytic leukemia: overview of genetic variants of cyclic nucleotide PDEs in human disease.

Published in:

Journal of Human Genetics, 2011, v. 56, n. 9, p. 676, doi. 10.1038/jhg.2011.80

By:

Peiró, Ana M;
Tang, Chih-Min;
Murray, Fiona;
Zhang, Lingzhi;
Brown, Loren M;
Chou, Daisy;
Rassenti, Laura;
Kipps, Thomas A;
Insel, Paul A

Publication type:

Article

Pentoxifylline and skin inflammation.

Published in:

Clinical & Experimental Dermatology, 1998, v. 23, n. 4, p. 168, doi. 10.1046/j.1365-2230.1998.00316.x

By:

BRUYNZEEL;
STOOF;
WILLEMZE

Publication type:

Article

The G protein preference of orexin receptors is currently an unresolved issue.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38764-3

By:

Kukkonen, Jyrki P.

Publication type:

Article

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages.

Published in:

PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008447

By:

Munday, Jane C.;
Kunz, Stefan;
Kalejaiye, Titilola D.;
Siderius, Marco;
Schroeder, Susanne;
Paape, Daniel;
Alghamdi, Ali H.;
Abbasi, Zainab;
Huang, Sheng Xiang;
Donachie, Anne-Marie;
William, Samia;
Sabra, Abdel Nasser;
Sterk, Geert Jan;
Botros, Sanaa S.;
Brown, David G.;
Hoffman, Charles S.;
Leurs, Rob;
de Koning, Harry P.

Publication type:

Article