Results
Title

Use of glycoprotein IIb/IIIa inhibitors in unstable angina and non-ST-elevation myocardial infarction.

Authors

Crosbie, Deanne J.

Abstract

Acute coronary syndromes (ACS) are a major cause of morbidity and mortality in Western society. The commonest underlying pathology is the coronary atherosclerotic plaque complicated by thrombosis. Platelets play a central role. As the glycoprotein IIb/IIIa receptor is involved in the final step of platelet thrombus formation development and investigation of its blockage in ACS is at the fore. Initial hospital management of ACS occur in the ED setting. The present article outlines the above topics and clarifies the place of glycoprotein IIb/IIIa receptor inhibition in ED.

Subjects

ATHEROSCLEROTIC plaque; THROMBOSIS; BLOOD platelets; GLYCOPROTEINS; CARDIOVASCULAR diseases; EPIDEMIOLOGY; MORTALITY

Publication

Emergency Medicine Australasia, 2005, Vol 17, Issue 5/6, p500

ISSN

1742-6731

Publication type

Academic Journal

DOI

10.1111/j.1742-6723.2005.00783.x