A comparison between the release of fluoride from sodium fluoride lozenges and bone meal tablets.

Lorentzen, B.; Birkeland, J. M.; Lökken, P.

The release of fluoride from a fluoride-containing bone meal tablet and a chewable sodium fluoride lozenge to 0.5 M perchloric acid, deionized water, and saliva was compared. In acid, all the fluoride was released from the bone meal tablet (0.25 mg F), while there was a poor release in water and saliva (2-10%). The release from the sodium fluoride lozenge (0.25 mg F) was essentially complete in water and saliva as well as in acid. Following sucking and chewing on a sodium fluoride lozenge, the mean salivary fluoride concentration increased from 0.04 to 36 parts/10[sup6] 5 min after intake. Concentrations exceeding the preintake level were still recorded after 20 mm. With the bone meal tablet, only a slight increase (to 0.2 parts/10[sup6]) in the salivary fluoride level was obtained.

SODIUM fluoride; DRUG tablets; SALIVARY glands; FLUID therapy; ORAL drug administration; SALIVA

Community Dentistry & Oral Epidemiology, 1976, Vol 4, Issue 4, p140

0301-5661

Academic Journal

10.1111/j.1600-0528.1976.tb00971.x