Works matching DE "MEVALONATE kinase"

Results: 232

SMARCB1 Deficiency as a Driver of the Hallmarks of Cancer in Rhabdoid Tumours: Novel Insights into Dysregulated Energy Metabolism, Emerging Targets, and Ongoing Clinical Trials.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 5, p. 304, doi. 10.3390/metabo15050304

By:

Shakerdi, Abdul L.;
Pidgeon, Graham P.

Publication type:

Article

Biometallorganische Chemie mit IspG und IspH: Struktur, Funktion und Hemmung der an der Isoprenoid-Biosynthese beteiligten [Fe4S4]-Proteine.

Published in:

Angewandte Chemie, 2014, v. 126, n. 17, p. 4382, doi. 10.1002/ange.201306712

By:

Wang, Weixue;
Oldfield, Eric

Publication type:

Article

Pseudiline: halogenierte, allosterische Inhibitoren des Enzyms IspD aus dem Mevalonat-unabhängigen Biosyntheseweg.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2267, doi. 10.1002/ange.201309557

By:

Kunfermann, Andrea;
Witschel, Matthias;
Illarionov, Boris;
Martin, René;
Rottmann, Matthias;
Höffken, H. Wolfgang;
Seet, Michael;
Eisenreich, Wolfgang;
Knölker, Hans ‐ Joachim;
Fischer, Markus;
Bacher, Adelbert;
Groll, Michael;
Diederich, François

Publication type:

Article

The mevalonate pathway as a metabolic requirement for autophagy–implications for growth control, proteostasis, and disease.

Published in:

2016

By:

Miettinen, Teemu P.;
Björklund, Mikael

Publication type:

Opinion

Long-Term Safety and Effectiveness of Canakinumab in Patients with MKD/HIDS: Interim Analysis of the RELIANCE Registry.

Published in:

Rheumatology & Therapy, 2025, v. 12, n. 1, p. 137, doi. 10.1007/s40744-024-00733-7

By:

Oommen, Prasad T.;
Kallinich, Tilmann;
Rech, Juergen;
Blank, Norbert;
Weber-Arden, Julia;
Kuemmerle-Deschner, Jasmin B.

Publication type:

Article

MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-024-02186-8

By:

Zhou, Changsheng;
Liu, Jia;
Hu, Xudong;
Lu, Lu;
Hou, Juan;
Wang, Jian;
Jiang, Liqun;
Huang, Shuangshuang;
Lin, Yu;
Liu, Luyao;
Cui, Lingling;
Liu, Yiqian;
Huang, Yufeng

Publication type:

Article

Relationship of SNP rs2645429 in Farnesyl-Diphosphate Farnesyltransferase 1 Gene Promoter with Susceptibility to Lung Cancer.

Published in:

International Journal of Genomics, 2018, p. 1, doi. 10.1155/2018/4863757

By:

Dehghani, Mehdi;
Samani, Zahra;
Abidi, Hassan;
Manzouri, Leila;
Mahmoudi, Reza;
Hosseini Teshnizi, Saeed;
Nikseresht, Mohsen

Publication type:

Article

Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma.

Published in:

Oncology Letters, 2019, v. 17, n. 2, p. 1523

By:

Zhao, Dan-Dan;
Yuan, Jun;
Cheng, Qi;
Qi, Ya-Ling;
Lu, Ke;
Lai, Shan-Shan;
Sun, Qian;
Zhao, Yue;
Fang, Lei;
Jin, Mei-Ling;
Yu, De-Cai;
Qiu, Yu-Dong;
Li, Chao-Jun;
Chen, Jun;
Xue, Bin

Publication type:

Article

Dynamics of Monoterpene Formation in Spike Lavender Plants.

Published in:

Metabolites (2218-1989), 2017, v. 7, n. 4, p. 65, doi. 10.3390/metabo7040065

By:

Mendoza-Poudereux, Isabel;
Kutzner, Erika;
Huber, Claudia;
Segura, Juan;
Arrillaga, Isabel;
Eisenreich, Wolfgang

Publication type:

Article

Long-Term Follow-Up and Optimization of Interleukin-1 Inhibitors in the Management of Monogenic Autoinflammatory Diseases: Real-Life Data from the JIR Cohort.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.568865

By:

Hentgen, Véronique;
Koné-Paut, Isabelle;
Belot, Alexandre;
Galeotti, Caroline;
Grateau, Gilles;
Carbasse, Aurelia;
Pagnier, Anne;
Pillet, Pascal;
Delord, Marc;
Hofer, Michael;
Georgin-Lavialle, Sophie

Publication type:

Article

Comparative Transcriptome Analysis of Genes Involved in Sesquiterpene Alkaloid Biosynthesis in Trichoderma longibrachiatum MD33 and UN32.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.800125

By:

Qian, Xu;
Jin, Hui;
Chen, Zhuojun;
Dai, Qingqing;
Sarsaiya, Surendra;
Qin, Yitong;
Jia, Qi;
Jin, Leilei;
Chen, Jishuang

Publication type:

Article

Defective Protein Prenylation in a Spectrum of Patients With Mevalonate Kinase Deficiency.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01900

By:

Munoz, Marcia A.;
Jurczyluk, Julie;
Simon, Anna;
Hissaria, Pravin;
Arts, Rob J. W.;
Coman, David;
Boros, Christina;
Mehr, Sam;
Rogers, Michael J.

Publication type:

Article

Effects of Lime Application on Activities of Related Enzymes and Protein Expression of Saponin Metabolism of Panax notoginseng under Cadmium Stress.

Published in:

Polish Journal of Environmental Studies, 2020, v. 29, n. 6, p. 4199, doi. 10.15244/pjoes/120514

By:

Zuran Li;
Yueqin Jiang;
Yanqun Zu;
Xinyue Mei;
Li Qin;
Bo Li

Publication type:

Article

Reply to 'Paradoxical hidradenitis suppurativa induced by adalimumab biosimilar successfully treated with guselkumab in a patient with psoriasis. Comment on "Paradoxical hidradenitis suppurativa due to anti-interleukin-1 agents for mevalonate kinase deficiency successfully treated with the addition of ustekinumab"'

Published in:

Clinical & Experimental Dermatology, 2023, v. 48, n. 8, p. 940, doi. 10.1093/ced/llad160

By:

Sanz, Pablo López;
Pérez, Marta Guzmán;
Ramírez, Claudia Guerrero;
Córdoba, Silvia Manso;
Martínez, María Encarnación Alfaro;
Defez, José Manuel Azaña

Publication type:

Article

Paradoxical hidradenitis suppurativa induced by adalimumab biosimilar successfully treated with guselkumab in a patient with psoriasis. Comment on 'Paradoxical hidradenitis suppurativa due to anti-interleukin-1 agents for mevalonate kinase deficiency successfully treated with the addition of ustekinumab'

Published in:

Clinical & Experimental Dermatology, 2023, v. 48, n. 6, p. 701, doi. 10.1093/ced/llad082

By:

Martora, Fabrizio;
Fabbrocini, Gabriella;
Marasca, Claudio;
Battista, Teresa;
Megna, Matteo

Publication type:

Article

Paradoxical hidradenitis suppurativa due to anti-interleukin-1 agents for mevalonate kinase deficiency successfully treated with the addition of ustekinumab.

Published in:

Clinical & Experimental Dermatology, 2023, v. 48, n. 5, p. 535, doi. 10.1093/ced/llad003

By:

Sanz, Pablo López;
Pérez, Marta Guzmán;
Defez, José Manuel Azaña;
Ramírez, Claudia Guerrero;
Córdoba, Silvia Manso;
Martínez, María Encarnación Alfaro

Publication type:

Article

Updating and identifying a novel mutation in the PMVK gene in classic porokeratosis of Mibelli.

Published in:

Clinical & Experimental Dermatology, 2017, v. 42, n. 8, p. 910, doi. 10.1111/ced.13197

By:

Song, N. J.;
Luan, J.;
Zhang, Z. H.

Publication type:

Article

Co-Expression Analysis Reveals Differential Expression of Homologous Genes Associated with Specific Terpenoid Biosynthesis in Rehmannia glutinosa.

Published in:

Genes, 2022, v. 13, n. 6, p. 1092, doi. 10.3390/genes13061092

By:

Kang, Ji-Nam;
Han, Jong-Won;
Yang, So-Hee;
Lee, Si-Myung

Publication type:

Article

Production of β-carotene and acetate in recombinant Escherichia coli with or without mevalonate pathway at different culture temperature or pH.

Published in:

Biotechnology & Bioprocess Engineering, 2012, v. 17, n. 6, p. 1196, doi. 10.1007/s12257-012-0272-2

By:

Nguyen, Anh;
Kim, Seon-Won;
Kim, Sung;
Seo, Yang-Gon;
Chung, In-Young;
Kim, Dae;
Kim, Chang-Joon

Publication type:

Article

FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity.

Published in:

Virulence, 2016, v. 7, n. 6, p. 718, doi. 10.1080/21505594.2016.1195537

By:

Wiesner, Jochen;
Ziemann, Christina;
Hintz, Martin;
Reichenberg, Armin;
Ortmann, Regina;
Schlitzer, Martin;
Fuhst, Rainer;
Timmesfeld, Nina;
Vilcinskas, Andreas;
Jomaa, Hassan

Publication type:

Article

Mevalonate kinase gene mutations and their clinical correlations in Behçet's disease.

Published in:

International Journal of Rheumatic Diseases, 2014, v. 17, n. 4, p. 435, doi. 10.1111/1756-185X.12243

By:

Arslan Taş, Didem;
Erken, Eren;
Yildiz, Fatih;
Dinkçi, Suzan;
Sakalli, Hakan

Publication type:

Article

Strategies of isoprenoids production in engineered bacteria.

Published in:

Journal of Applied Microbiology, 2016, v. 121, n. 4, p. 932, doi. 10.1111/jam.13237

By:

Li, Y.;
Wang, G.

Publication type:

Article

Enzymatic process optimization for the in vitro production of isoprene from mevalonate.

Published in:

Microbial Cell Factories, 2017, v. 16, p. 1, doi. 10.1186/s12934-016-0622-4

By:

Tao Cheng;
Hui Liu;
Huibin Zou;
Ningning Chen;
Mengxun Shi;
Congxia Xie;
Guang Zhao;
Mo Xian

Publication type:

Article

Combinatory optimization of chromosomal integrated mevalonate pathway for β-carotene production in Escherichia coli.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0607-3

By:

Lijun Ye;
Chunzhi Zhang;
Changhao Bi;
Qingyan Li;
Xueli Zhang

Publication type:

Article

ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0447-1

By:

Rodriguez, Sarah;
Denby, Charles M.;
Van Vu, T.;
Baidoo, Edward E. K.;
Wang, George;
Keasling, Jay D.

Publication type:

Article

Combinatorial engineering of hybrid mevalonate pathways in Escherichia coli for protoilludene production.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0409-7

By:

Liyang Yang;
Chonglong Wang;
Jia Zhou;
Seon-Won Kim

Publication type:

Article

Exometabolome analysis reveals hypoxia at the upscaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process.

Published in:

Microbial Cell Factories, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2859-13-32

By:

Zhibiao Fu;
Verderame, Thomas D.;
Leighton, Julie M.;
Sampey, Brante P.;
Appelbaum, Edward R.;
Patel, Pramatesh S.;
Aon, Juan C.

Publication type:

Article

Chemically induced mouse liver tumors are resistant to treatment with atorvastatin.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-766

By:

Braeuning, Albert;
Bucher, Philip;
Hofmann, Ute;
Buchmann, Albrecht;
Schwarz, Michael

Publication type:

Article

A linear pathway for mevalonate production supports growth of Thermococcus kodakarensis.

Published in:

Extremophiles, 2019, v. 23, n. 2, p. 229, doi. 10.1007/s00792-019-01076-w

By:

Liman, Geraldy L. S.;
Hulko, Tyler;
Febvre, Hallie P.;
Brachfeld, Aaron C.;
Santangelo, Thomas J.

Publication type:

Article

Real-world safety and effectiveness of canakinumab in patients with tumour necrosis factor receptor-associated periodic syndrome or hyperimmunoglobulinaemia D syndrome: Interim results from post-marketing surveillance in Japan.

Published in:

Modern Rheumatology, 2023, v. 33, n. 2, p. 381, doi. 10.1093/mr/roac041

By:

Kumiko Hosono;
Kazuko Matsumoto;
Miki Shimbo;
Isao Tsumiyama;
Chihiro Kato

Publication type:

Article

A case report of Hyper‐IgD syndrome in a 5‐year‐old girl with recurrent fever, skin rash, and arthralgia; novel MVK mutation (C.298G>A).

Published in:

2024

By:

Tabibi, Pooneh;
Shiari, Reza;
Ghotb Abadi, Shabnam Hajiani

Publication type:

Case Study

Analysis of OeMVK Gene Expression in Different Olive Tissues Using Real Time PCR.

Published in:

Adiyaman University Journal of Science & Technology / Adıyaman Üniversitesi Fen Bilimleri Dergisi, 2019, v. 9, n. 2, p. 230, doi. 10.37094/adyujsci.530868

By:

DENİZ SÖNMEZ, Görkem

Publication type:

Article

Cloning and expression analysis of mevalonate kinase and phosphomevalonate kinase genes associated with the MVA pathway in Santalum album.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-96511-4

By:

Niu, Meiyun;
Xiong, Yuping;
Yan, Haifeng;
Zhang, Xinhua;
Li, Yuan;
da Silva, Jaime A. Teixeira;
Ma, Guohua

Publication type:

Article

Bayesian Optimization for an ATP-Regenerating In Vitro Enzyme Cascade.

Published in:

Catalysts (2073-4344), 2023, v. 13, n. 3, p. 468, doi. 10.3390/catal13030468

By:

Siedentop, Regine;
Siska, Maximilian;
Möller, Niklas;
Lanzrath, Hannah;
von Lieres, Eric;
Lütz, Stephan;
Rosenthal, Katrin

Publication type:

Article

Enhanced (−)-α-Bisabolol Productivity by Efficient Conversion of Mevalonate in Escherichia coli.

Published in:

Catalysts (2073-4344), 2019, v. 9, n. 5, p. 432, doi. 10.3390/catal9050432

By:

Kim, Soo-Jung;
Kim, Seong Keun;
Seong, Wonjae;
Woo, Seung-Gyun;
Lee, Hyewon;
Yeom, Soo-Jin;
Kim, Haseong;
Lee, Dae-Hee;
Lee, Seung-Goo

Publication type:

Article

Mevalonate kinase-deficient THP-1 cells show a disease-characteristic pro-inflammatory phenotype.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1379220

By:

Politiek, Frouwkje A.;
Turkenburg, Marjolein;
Ofman, Rob;
Waterham, Hans R.

Publication type:

Article

Activation of the plant mevalonate pathway by extracellular ATP.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28150-w

By:

Cho, Sung-Hwan;
Tóth, Katalin;
Kim, Daewon;
Vo, Phuc H.;
Lin, Chung-Ho;
Handakumbura, Pubudu P.;
Ubach, Albert Rivas;
Evans, Sterling;
Paša-Tolić, Ljiljana;
Stacey, Gary

Publication type:

Article

Nonselective Mevalonate Kinase Inhibitor as a Novel Class of Antibacterial Agents.

Published in:

Cholesterol, 2015, v. 2015, p. 1, doi. 10.1155/2015/147601

By:

Gharehbeglou, Mohammad;
Arjmand, Ghasem;
Haeri, Mohammad Reza;
Khazeni, Mohammad

Publication type:

Article

INVESTIGATIONS ON 3-HYDROXY-3-METHYLGLUTARYL COA REDUCTASE ENZYME FROM DIFFERENT SOURCE ORGANISMS.

Published in:

Journal of Nature Science & Sustainable Technology, 2015, v. 9, n. 4, p. 725

By:

Adhikari, Utpal Kumar;
Hossain, Md. Sazzad;
Rahman, M. Mizanur

Publication type:

Article

T lymphocyte regulation by mevalonate metabolism.

Published in:

Science Signaling, 2015, v. 8, n. 370, p. 1, doi. 10.1126/scisignal.2005970

By:

Thurnher, Martin;
Gruenbacher, Georg

Publication type:

Article

Validation of liquid chromatography-tandem mass spectrometry for mevalonate in human plasma: Incompetent effects between treated atorvastatin & its combination with olmesartan in cardiovascular patients.

Published in:

Journal of Young Pharmacists, 2014, v. 6, n. 2, p. 50, doi. 10.5530/jyp.2014.2.8

By:

Das, Rakesh;
Pal, Tapan Kumar

Publication type:

Article

Large-Scale Evolutionary Analysis of Genes and Supergene Clusters from Terpenoid Modular Pathways Provides Insights into Metabolic Diversification in Flowering Plants.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128808

By:

Hofberger, Johannes A.;
Ramirez, Aldana M.;
Bergh, Erik van den;
Zhu, Xinguang;
Bouwmeester, Harro J.;
Schuurink, Robert C.;
Schranz, M. Eric

Publication type:

Article

Loss of HMG-CoA Reductase in C. elegans Causes Defects in Protein Prenylation and Muscle Mitochondria.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100033

By:

Ranji, Parmida;
Rauthan, Manish;
Pitot, Christophe;
Pilon, Marc

Publication type:

Article

Chemical and Genetic Validation of the Statin Drug Target to Treat the Helminth Disease, Schistosomiasis.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087594

By:

Rojo-Arreola, Liliana;
Long, Thavy;
Asarnow, Dan;
Suzuki, Brian M.;
Singh, Rahul;
Caffrey, Conor R.

Publication type:

Article

Kinetics of Phosphomevalonate Kinase from Saccharomyces cerevisiae.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087112

By:

Garcia, David E.;
Keasling, Jay D.

Publication type:

Article

Exploration of Virtual Candidates for Human HMG-CoA Reductase Inhibitors Using Pharmacophore Modeling and Molecular Dynamics Simulations.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083496

By:

Son, Minky;
Baek, Ayoung;
Sakkiah, Sugunadevi;
Park, Chanin;
John, Shalini;
Lee, Keun Woo

Publication type:

Article

Selective Role of Mevalonate Pathway in Regulating Perforin but Not FasL and TNFalpha Release in Human Natural Killer Cells

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062932

By:

Poggi, Alessandro;
Boero, Silvia;
Musso, Alessandra;
Zocchi, Maria Raffaella

Publication type:

Article

Metabolite Profiling Identified Methylerythritol Cyclodiphosphate Efflux as a Limiting Step in Microbial Isoprenoid Production.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0047513

By:

Kang Zhou;
Ruiyang Zou;
Stephanopoulos, Gregory;
Heng-Phon Too

Publication type:

Article

Effect of Levels of Acetate on the Mevalonate Pathway of Borrelia burgdorferi.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0038171

By:

Van Laar, Tricia A.;
Ying-Han Lin;
Miller, Christine L.;
Rajasekhar Karna, S. L.;
Chambers, James P.;
Seshu, J.

Publication type:

Article

P149 Role of the mevalonate pathway in myocardial postconditioning.

Published in:

Cardiovascular Research, 2014, v. 103, n. suppl_1, p. S26, doi. 10.1093/cvr/cvu082.88

By:

Szucs, G;
Murlasits, Z;
Csonka, C;
Ferdinandy, P

Publication type:

Article