Works matching IS 00071188 AND DT 2010 AND VI 160 AND IP 2

Results: 22

Challenges for and current status of research into positive modulators of AMPA receptors.
Published in:
2010
By:
- Ward, Simon E;
- Bax, Benjamin D;
- Harries, Mark
Publication type:
journal article
Methylenedioxymethamphetamine inhibits mitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity.
Published in:
2010
By:
- Puerta, Elena;
- Hervias, Isabel;
- Goñi-Allo, Beatriz;
- Zhang, Steven F;
- Jordán, Joaquín;
- Starkov, Anatoly A;
- Aguirre, Norberto;
- Goñi-Allo, Beatriz;
- Jordán, Joaquín
Publication type:
journal article
Enhancement of inflammatory mediator release by beta(2)-adrenoceptor agonists in airway epithelial cells is reversed by glucocorticoid action.
Published in:
2010
By:
- Holden, NS;
- Rider, CF;
- Bell, MJ;
- Velayudhan, J;
- King, EM;
- Kaur, M;
- Salmon, M;
- Giembycz, MA;
- Newton, R;
- Holden, N S;
- Rider, C F;
- Bell, M J;
- King, E M;
- Giembycz, M A
Publication type:
journal article
Estimation of binding rate constants using a simultaneous mixed-effects method: application to monoamine transporter reuptake inhibitor reboxetine.
Published in:
2010
By:
- Benson, Neil;
- Snelder, Nelleke;
- Ploeger, Bart;
- Napier, Carolyn;
- Sale, Harriet;
- JM Birdsall, Nigel;
- Butt, Richard P;
- Van Der Graaf, Piet H;
- Birdsall, Nigel J M
Publication type:
journal article
The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by ß-amyloid peptide.
Published in:
British Journal of Pharmacology, 2010, v. 160, n. 2, p. 246, doi. 10.1111/j.1476-5381.2010.00656.x
By:
- Kurz, C;
- Ungerer, I;
- Lipka, U;
- Kirr, S;
- Schütt, T;
- Eckert, A;
- Leuner, K;
- Müller, WE
Publication type:
Article
Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus.
Published in:
2010
By:
- Andújar, I;
- Recio, MC;
- Bacelli, T;
- Giner, RM;
- Ríos, JL;
- Andújar, I;
- Recio, M C;
- Giner, R M;
- Ríos, J L
Publication type:
journal article
Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity.
Published in:
2010
By:
- Silva, Jean Jerley Nogueira;
- Guedes, Paulo Marcos Matta;
- Zottis, Aderson;
- Balliano, Tatiane Luciano;
- Nascimento Silva, Francisco Ordelei;
- França Lopes, Luiz Gonzaga;
- Ellena, Javier;
- Oliva, Glaucius;
- Andricopulo, Adriano Defini;
- Franco, Douglas Wagner;
- Silva, João Santana;
- França Lopes, Luiz Gonzaga;
- Silva, João Santana
Publication type:
journal article
Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane-targeted alkylphospholipid analogues.
Published in:
2010
By:
- Carrasco, María P;
- Jiménez-López, José M;
- Ríos-Marco, Pablo;
- Segovia, Josefa L;
- Marco, Carmen;
- Carrasco, María P;
- Jiménez-López, José M;
- Ríos-Marco, Pablo
Publication type:
journal article
High-throughput screening and small animal models, where are we?
Published in:
British Journal of Pharmacology, 2010, v. 160, n. 2, p. 204, doi. 10.1111/j.1476-5381.2010.00725.x
By:
- Giacomotto, Jean;
- Ségalat, Laurent
Publication type:
Article
New drugs for neglected infectious diseases: Chagas' disease.
Published in:
2010
By:
- Machado, Fabiana S;
- Tanowitz, Herbert B;
- Teixeira, Mauro M
Publication type:
journal article
Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations.
Published in:
2010
By:
- Ludolph, Andrea G;
- Udvardi, Patrick T;
- Schaz, Ulrike;
- Henes, Carolin;
- Adolph, Oliver;
- Weigt, Henry U;
- Fegert, Joerg M;
- Boeckers, Tobias M;
- Föhr, Karl J;
- Föhr, Karl J
Publication type:
journal article
Selective alpha7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis.
Published in:
2010
By:
- Snoek, Susanne A;
- Verstege, Marleen I;
- Van Der Zanden, Esmerij P;
- Deeks, Nigel;
- Bulmer, David C;
- Skynner, Michael;
- Lee, Kevin;
- Te Velde, Anje A;
- Boeckxstaens, Guy E;
- De Jonge, Wouter J
Publication type:
journal article
A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse.
Published in:
2010
By:
- Julio-Pieper, M;
- Hyland, NP;
- Bravo, JA;
- Dinan, TG;
- Cryan, JF;
- Hyland, N P;
- Bravo, J A;
- Dinan, T G;
- Cryan, J F
Publication type:
journal article
Mitochondria as pharmacological targets.
Published in:
2010
By:
- Moncada, S
Publication type:
journal article
A novel antagonist of the prostaglandin E(2) EP(4) receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models.
Published in:
2010
By:
- Chen, Q;
- Muramoto, K;
- Masaaki, N;
- Ding, Y;
- Yang, H;
- Mackey, M;
- Li, W;
- Inoue, Y;
- Ackermann, K;
- Shirota, H;
- Matsumoto, I;
- Spyvee, M;
- Schiller, S;
- Sumida, T;
- Gusovsky, F;
- Lamphier, M
Publication type:
journal article
Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion.
Published in:
2010
By:
- Pravdic, D;
- Mio, Y;
- Sedlic, F;
- Pratt, PF;
- Warltier, DC;
- Bosnjak, ZJ;
- Bienengraeber, M;
- Pratt, P F;
- Warltier, D C;
- Bosnjak, Z J
Publication type:
journal article
Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT(2)) receptor.
Published in:
2010
By:
- Wunder, F;
- Tinel, H;
- Kast, R;
- Geerts, A;
- Becker, EM;
- Kolkhof, P;
- Hütter, J;
- Ergüden, J;
- Härter, M;
- Becker, E M;
- Hütter, J;
- Ergüden, J;
- Härter, M
Publication type:
journal article
Ouabain attenuates cardiotoxicity induced by other cardiac steroids.
Published in:
2010
By:
- Nesher, M;
- Shpolansky, U;
- Viola, N;
- Dvela, M;
- Buzaglo, N;
- Ben-Ami, H Cohen;
- Rosen, H;
- Lichtstein, D;
- Cohen Ben-Ami, H
Publication type:
journal article
Signal transduction by protease-activated receptors.
Published in:
2010
By:
- Soh, Unice JK;
- Dores, Michael R;
- Chen, Buxin;
- Trejo, JoAnn;
- Soh, Unice J K
Publication type:
journal article
Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.
Published in:
2010
By:
- Rollema, H;
- Shrikhande, A;
- Ward, KM;
- Tingley III, FD;
- Coe, JW;
- O'Neill, BT;
- Tseng, E;
- Wang, EQ;
- Mather, RJ;
- Hurst, RS;
- Williams, KE;
- De Vries, M;
- Cremers, T;
- Bertrand, S;
- Bertrand, D;
- Ward, K M;
- Tingley, F D 3rd;
- Coe, J W;
- O'Neill, B T;
- Wang, E Q
Publication type:
journal article
Increased brain damage after ischaemic stroke in mice lacking the chemokine receptor CCR5.
Published in:
2010
By:
- Sorce, S;
- Bonnefont, J;
- Julien, S;
- Marq-Lin, N;
- Rodriguez, I;
- Dubois-Dauphin, M;
- Krause, KH;
- Krause, K H
Publication type:
journal article
Nitric oxide donor trans-[RuCl([15]aneN)NO] as a possible therapeutic approach for Chagas' disease.
Published in:
2010
By:
- Guedes, Paulo MM;
- Oliveira, Fabiana S;
- Gutierrez, Fredy RS;
- Da Silva, Grace Kelly;
- Rodrigues, Gerson Jhonatan;
- Bendhack, Lusiane Maria;
- Franco, Douglas W;
- Do Valle Matta, Maria A;
- Zamboni, Dario S;
- Da Silva, Roberto Santana;
- Silva, João Santana;
- Guedes, Paulo M M;
- Gutierrez, Fredy R S;
- Silva, João Santana
Publication type:
journal article