Works matching AU Hontecillas, Raquel
Results: 54
Safety, Tolerability, and Pharmacokinetics of NIM‐1324 an Oral LANCL2 Agonist in a Randomized, Double‐Blind, Placebo‐Controlled Phase I Clinical Trial.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 1, p. 1, doi. 10.1111/cts.70129
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- Article
Arachidonic acid- and docosahexaenoic acid-enriched formulas modulate antigen-specific T cell responses against influenza virus in neonatal piglets.
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- FASEB Journal, 2007, v. 21, n. 5, p. A377, doi. 10.1096/fasebj.21.5.a377
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- Article
Immunomodulatory properties of long-term dietary supplementation with abscisic acid.
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- FASEB Journal, 2007, v. 21, n. 5, p. A376, doi. 10.1096/fasebj.21.5.a376-c
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- Article
The loss of PPAR γ in immune cells abrogates the ability of abscisic acid to improve insulin sensitivity through a mechanism involving suppression of MCP-1 expression and macrophage infiltration into white adipose tissue.
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- FASEB Journal, 2007, v. 21, n. 5, p. A64
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- Article
Multiscale modeling of mucosal immune responses.
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- BMC Bioinformatics, 2015, v. 16, p. 1, doi. 10.1186/1471-2105-16-S12-S2
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- Article
Increasing the Density of Laboratory Measures for Machine Learning Applications.
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- Journal of Clinical Medicine, 2021, v. 10, n. 1, p. 103, doi. 10.3390/jcm10010103
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- Article
Modulation of colonic immunometabolic responses during Clostridioides difficile infection ameliorates disease severity and inflammation.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41847-2
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- Article
Modulation of colonic immunometabolic responses during Clostridioides difficile infection ameliorates disease severity and inflammation.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41847-2
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- Article
Nlrx1-Regulated Defense and Metabolic Responses to Aspergillus fumigatus Are Morphotype and Cell Type Specific.
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- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.749504
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- Article
Pharmacophore modeling improves virtual screening for novel peroxisome proliferator-activated receptor-gamma ligands.
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- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 5, p. 421, doi. 10.1007/s10822-015-9831-x
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- Article
Treatment of Obesity-Related Complications with Novel Classes of Naturally Occurring PPAR Agonists.
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- 2011
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- Journal Article
Treatment of Obesity-Related Complications with Novel Classes of Naturally Occurring PPAR Agonists.
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- Journal of Obesity, 2011, v. 2011, p. 1, doi. 10.1155/2011/897894
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- Article
Deletion of PPAR-γ in immune cells enhances susceptibility to antiglomerular basement membrane disease.
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- Journal of Inflammation Research, 2010, v. 3, p. 127, doi. 10.2147/JIR.S13394
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- Article
Modeling-Enabled Characterization of Novel NLRX1 Ligands.
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- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145420
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- Article
Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection.
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- PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137839
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- Article
Sensitivity Analysis of an ENteric Immunity SImulator (ENISI)-Based Model of Immune Responses to Helicobacter pylori Infection.
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- PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0136139
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- Article
Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection.
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- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0134849
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- Article
Investigation of chloroform-methanol soluble wheat proteins and sphingolipids as potential dietary triggers of diabetes in BBdp rats.
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- Food & Agricultural Immunology, 2008, v. 19, n. 1, p. 25, doi. 10.1080/09540100801915345
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- Article
Molecular modeling of lanthionine synthetase component C-like protein 2: a potential target for the discovery of novel type 2 diabetes prophylactics and therapeutics.
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- Journal of Molecular Modeling, 2011, v. 17, n. 3, p. 543, doi. 10.1007/s00894-010-0748-y
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- Article
Systems Modeling of Molecular Mechanisms Controlling Cytokine-driven CD4+ T Cell Differentiation and Phenotype Plasticity.
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- PLoS Computational Biology, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pcbi.1003027
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- Article
First-in-class topical therapeutic omilancor ameliorates disease severity and inflammation through activation of LANCL2 pathway in psoriasis.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99349-y
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- Article
Lanthionine Synthetase C-Like 2 Modulates Immune Responses to Influenza Virus Infection.
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- Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00178
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- Article
Mucosal interactions between Genetics, Diet, and Microbiome in inflammatory Bowel Disease.
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- Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00290
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- Article
Gene regulatory network reveals oxidative stress as the underlying molecular mechanism of type 2 diabetes and hypertension.
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- BMC Medical Genomics, 2010, v. 3, p. 45, doi. 10.1186/1755-8794-3-45
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- Article
Enemy of My Enemy: A Novel Insect-Specific Flavivirus Offers a Promising Platform for a Zika Virus Vaccine.
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- Vaccines, 2021, v. 9, n. 10, p. 1142, doi. 10.3390/vaccines9101142
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- Article
High-resolution computational modeling of immune responses in the gut.
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- GigaScience, 2019, v. 8, n. 6, p. 1, doi. 10.1093/gigascience/giz062
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- Article
Modeling the Mechanisms by Which HIV-Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa.
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- PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0168133
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- Article
Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection.
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- PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167440
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- Article
CD4<sup>+</sup> T-cell responses and distribution at the colonic mucosa duringBrachyspira hyodysenteriae-induced colitis in pigs.
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- Immunology, 2005, v. 115, n. 1, p. 127, doi. 10.1111/j.1365-2567.2005.02124.x
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- Article
Dietary Modulation of Inflammation-Induced Colorectal Cancer through PPARγ.
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- PPAR Research, 2009, p. 1, doi. 10.1155/2009/498352
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- Article
Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1.
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- Drug & Chemical Toxicology, 2022, v. 45, n. 1, p. 209, doi. 10.1080/01480545.2019.1679828
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- Article
Abscisic Acid Standardized Fig (Ficus carica) Extracts Ameliorate Postprandial Glycemic and Insulinemic Responses in Healthy Adults.
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- Nutrients, 2019, v. 11, n. 8, p. 1757, doi. 10.3390/nu11081757
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- Article
Supervised learning methods in modeling of CD4+ T cell heterogeneity.
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- BioData Mining, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13040-015-0060-6
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- Article
Computational modeling of complex bioenergetic mechanisms that modulate CD4+ T cell effector and regulatory functions.
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- NPJ Systems Biology & Applications, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41540-022-00263-4
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- Article
Identification of new regulatory genes through expression pattern analysis of a global RNA-seq dataset from a Helicobacter pylori co-culture system.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68439-8
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- Article
Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67300-2
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- Article
Modulation of hepatic PPAR expression during Ft LVS LPS-induced protection from Francisella tularensis LVS infection.
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- BMC Infectious Diseases, 2010, v. 10, n. 1, p. 1, doi. 10.1186/1471-2334-10-10
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- Article
NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis.
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- PLoS Pathogens, 2020, v. 16, n. 9, p. 1, doi. 10.1371/journal.ppat.1008854
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- Article
Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records.
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- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.638913
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- Article
Systems-wide analyses of mucosal immune responses to Helicobacter pylori at the interface between pathogenicity and symbiosis.
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- Gut Microbes, 2016, v. 7, n. 1, p. 3, doi. 10.1080/19490976.2015.1116673
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- Article
Zinc deficiency alters host response and pathogen virulence in a mouse model of enteroaggregative escherichia coli -induced diarrhea.
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- Gut Microbes, 2014, v. 5, n. 5, p. 618, doi. 10.4161/19490976.2014.969642
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- Article
Novel insights on the role of CD8+ T cells and cytotoxic responses during Helicobacter pylori infection.
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- Gut Microbes, 2014, v. 5, n. 3, p. 1, doi. 10.4161/gmic.28899
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- Article
Animal models of enteroaggregative Escherichia coli infection.
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- Gut Microbes, 2013, v. 4, n. 4, p. 281, doi. 10.4161/gmic.24826
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- Article
Predictive Computational Modeling of the Mucosal Immune Responses during <i>Helicobacter pylori</i> Infection.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073365
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- Article
The Role of Peroxisome Proliferator-Activated Receptor γ in Immune Responses to Enteroaggregative <i>Escherichia coli</i> Infection.
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- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057812
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- Article
Helicobacter pylori Colonization Ameliorates Glucose Homeostasis in Mice through a PPAR γ-Dependent Mechanism.
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- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050069
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- Article
Modeling the Role of Peroxisome Proliferator-Activated Receptor c and MicroRNA-146 in Mucosal Immune Responses to Clostridium difficile.
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- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047525
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- Publication type:
- Article
Immunoregulatory Mechanisms Underlying Prevention of Colitis-Associated Colorectal Cancer by Probiotic Bacteria.
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- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034676
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- Publication type:
- Article
Computational Modeling-Based Discovery of Novel Classes of Anti-Inflammatory Drugs That Target Lanthionine Synthetase C-Like Protein 2.
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- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034643
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- Article
Probiotic Bacteria Produce Conjugated Linoleic Acid Locally in the Gut That Targets Macrophage PPAR γ to Suppress Colitis.
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- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031238
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- Article