Works matching DE "THROMBOPOIETIN"

Results: 572

Expression and functional analysis of the novel c-Mpl splice variant c-Mpl-D in acute myeloid leukemia.

Published in:

Acta Scientiarum Naturalium Universitatis Sunyatseni / Zhongshan Daxue Xuebao, 2025, v. 64, n. 3, p. 47, doi. 10.13471/j.cnki.acta.snus.ZR20240274

By:

WANG Jiasheng;
LI Fei;
HE Yue;
WU Leyan;
LI Chunmou;
ZENG Maozhen;
CHEN Junru;
CHEN Haisheng;
GUO Qiqi;
FAN Jiaxi;
WANG Qi;
HUANG Xuan;
CHEN Weiting;
ZHANG Qing

Publication type:

Article

Thrombopoietic agents enhance bone healing in mice, rats, and pigs.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 1, p. 125, doi. 10.1093/jbmr/zjae191

By:

Childress, Paul J;
Nielsen, Jeffery J;
Bemenderfer, Thomas B;
Dadwal, Ushashi C;
Chakraborty, Nabarun;
Harris, Jonathan S;
Bethel, Monique;
Alvarez, Marta B;
Tucker, Aamir;
Wessel, Alexander R;
Millikan, Patrick D;
Wilhite, Jonathan H;
Engle, Andrew;
Brinker, Alexander;
Rytlewski, Jeffrey D;
Scofield, David C;
Griffin, Kaitlyn S;
Shelley, W Christopher;
Manikowski, Kelli J;
Jackson, Krista L

Publication type:

Article

Eltrombopag for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura.

Published in:

Oncology (08909091), 2009, v. 23, n. 13, p. 1171

By:

Andrew Dmytrijuk;
Robie-Such, Kathy;
Rieves, Dwaine;
Pazdur, Richard

Publication type:

Article

The Road to Romiplostim Approval and Beyond.

Published in:

Oncology (08909091), 2009, v. 23, n. 8, p. 709

By:

Lyman, Gary H.

Publication type:

Article

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 971, doi. 10.1038/nsmb.2099

By:

Ungureanu, Daniela;
Jinhua Wu;
Pekkala, Tuija;
Niranjan, Yashavanthi;
Young, Clifford;
Jensen, Ole N.;
Chong-Feng Xu;
Neubert, Thomas A.;
Skoda, Radek C.;
Hubbard, Stevan R.;
Silvennoinen, Olli

Publication type:

Article

Differential localization of P-selectin and von Willebrand factor during megakaryocyte maturation.

Published in:

Biotechnic & Histochemistry, 2010, v. 85, n. 3, p. 157, doi. 10.3109/10520290903149612

By:

Zingariello1, M;
Fabucci, ME;
Bosco, D;
Migliaccio, AR;
Martelli, F;
Rana, RA;
Zetterberg, E

Publication type:

Article

Optimizing Optimata.

Published in:

Bio-IT World, 2005, v. 4, n. 11, p. 46

By:

Russell, John

Publication type:

Article

Expression, purification and characterization of soluble human thrombopoietin receptor from Escherichia coli.

Published in:

Biotechnology Letters, 2000, v. 22, n. 20, p. 1611, doi. 10.1023/A:1005672824663

By:

Heungrok Park;
Hana Im;
Young Jun Kang;
Myeong-Hee Yu;
Hyo Jeong Hong

Publication type:

Article

Normal and pathological dynamics of platelets in humans.

Published in:

Journal of Mathematical Biology, 2017, v. 75, n. 6/7, p. 1411, doi. 10.1007/s00285-017-1125-6

By:

Langlois, Gabriel;
Craig, Morgan;
Humphries, Antony;
Mackey, Michael;
Mahaffy, Joseph;
Bélair, Jacques;
Moulin, Thibault;
Sinclair, Sean;
Wang, Liangliang

Publication type:

Article

Eltrombopag, an oral thrombopoietin receptor agonist, has no impact on the pharmacokinetic profile of probe drugs for cytochrome P450 isoenzymes CYP3A4, CYP1A2, CYP2C9 and CYP2C19 in healthy men: a cocktail analysis.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 1, p. 67, doi. 10.1007/s00228-009-0716-6

By:

Jenkins, Julian;
Williams, Daphne;
Deng, Yanli;
Collins, David;
Kitchen, Valerie

Publication type:

Article

Thrombopoietin modulates cardiac contractility in vitro and contributes to myocardial depressing activity of septic shock serum.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 5, p. 609, doi. 10.1007/s00395-010-0103-6

By:

Lupia, Enrico;
Spatola, Tiziana;
Cuccurullo, Alessandra;
Bosco, Ornella;
Mariano, Filippo;
Pucci, Angela;
Ramella, Roberta;
Alloatti, Giuseppe;
Montrucchio, Giuseppe

Publication type:

Article

Expression, refolding, and characterization of recombinant thrombopoietin/stem cell factor fusion protein in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 74, n. 4, p. 836, doi. 10.1007/s00253-006-0734-6

By:

Yuhui Zang;
Xu Zhang;
Xiaoling Jiang;
Haoran Li;
Jie Zhu;
Chi Zhang;
Wei Peng;
Junchuan Qin

Publication type:

Article

Down-regulation of lactate dehydrogenase-A by siRNAs for reduced lactic acid formation of Chinese hamster ovary cells producing thrombopoietin.

Published in:

Applied Microbiology & Biotechnology, 2007, v. 74, n. 1, p. 152, doi. 10.1007/s00253-006-0654-5

By:

Sung Hyun Kim;
Gyun Min Lee

Publication type:

Article

Yeast hydrolysate as a low-cost additive to serum-free medium for the production of human thrombopoietin in suspension cultures of Chinese hamster ovary cells.

Published in:

Applied Microbiology & Biotechnology, 2004, v. 63, n. 5, p. 527, doi. 10.1007/s00253-003-1389-1

By:

Sung, Y. H.;
Lim, S. W.;
Chung, J. Y.;
Lee, G. M.

Publication type:

Article

Therapeutic roles of hematopoietic growth factors: treatment with a thrombopoietin mimetic (Eltrombopag) and cyclosporin A in aplastic anemia.

Published in:

Egyptian Journal of Haematology, 2022, v. 47, n. 2, p. 105, doi. 10.4103/ejh.ejh_11_22

By:

Khaled, Safaa;
Mahmoud, Maged;
Mahran, Dalia;
Abdelaal, Sawsan;
Hussein, Safinaz

Publication type:

Article

Safety, Pharmacokinetics and Pharmacodynamics of Hetrombopag Olamine, a Novel TPO-R Agonist, in Healthy Individuals.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2017, v. 121, n. 5, p. 414, doi. 10.1111/bcpt.12815

By:

Zheng, Li;
Liang, Mao‐zhi;
Zeng, Xiao‐ling;
Li, Cai‐zheng;
Zhang, Yi‐fan;
Chen, Xiao‐yan;
Zhu, Xi;
Xiang, An‐bo

Publication type:

Article

Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity.

Published in:

Oncology Letters, 2018, v. 15, n. 1, p. 839, doi. 10.3892/ol.2017.7410

By:

Wang, Han;
Wang, Hua;
Liang, En-Yu;
Zhou, Li-Xia;
Dong, Zhan-Ling;
Liang, Ping;
Weng, Qi-Fang;
Yang, Mo

Publication type:

Article

Normal platelet counts mask abnormal thrombopoiesis in patients with chronic myeloid leukemia.

Published in:

Oncology Letters, 2015, v. 10, n. 4, p. 2390, doi. 10.3892/ol.2015.3502

By:

KAILI YAN;
BANGSHENG DING;
JIANYAO HUANG;
YUANYUAN DAI;
SHUDAO XIONG;
ZHIMIN ZHAI

Publication type:

Article

Usefulness of short-term eltrombopag treatment as a supportive treatment in hepatocellular carcinoma patients with cirrhosis and severe thrombocytopenia: A report of two cases.

Published in:

2014

By:

TAKUMI KAWAGUCHI;
MASAHITO NAKANO;
MANABU SATANI;
SHUJI SUMIE;
SHINGO YAMADA;
KEISUKE AMANO;
RYOKO KUROMATSU;
MICHIO SATA

Publication type:

Case Study

Correlation Between Serum Thrombopoietin Level and Cirrhosis Clinical Stage in Liver Cirrhosis Patients in Mohammad Hoesin Palembang Hospital and Palembang BARI Hospital.

Published in:

Indonesian Journal of Gastroenterology, Hepatology & Digestive Endoscopy, 2015, v. 16, n. 3, p. 153, doi. 10.24871/1632015153-159

By:

Astoni, Muhamad Ayus;
Bakry, Fuad;
Saleh, Irsan

Publication type:

Article

Efficacy and Safety of Recombinant Human Thrombopoietin on Sepsis Patients With Thrombocytopenia: A Systematic Review and Meta-Analysis.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00940

By:

Zhang, Jin;
Lu, Zongqing;
Xiao, Wenyan;
Hua, Tianfeng;
Zheng, Yao;
Yang, Min

Publication type:

Article

Thrombopoietin, flt3-ligand and c-kit-ligand modulate HOX gene expression in expanding cord blood CD133+ cells.

Published in:

Cell Proliferation, 2004, v. 37, n. 4, p. 295, doi. 10.1111/j.1365-2184.2004.00313.x

By:

McGuckin, C.P.;
Forraz, N.;
Pettengell, R.;
Thompson, A.

Publication type:

Article

Romiplostim as a treatment for immune thrombocytopenia: a review.

Published in:

Journal of Blood Medicine, 2015, v. 6, p. 37, doi. 10.2147/JBM.S47240

By:

Chalmers, Sarah;
Tarantino, Michael D.

Publication type:

Article

Romiplostim (AMG531, Nplate) for secondary failure of platelet recovery after allo-SCT.

Published in:

2011

By:

Calmettes, C;
Vigouroux, S;
Tabrizi, R;
Milpied, N

Publication type:

Letter

Transplantation of ex vivo expanded cord blood cells using the copper chelator tetraethylenepentamine: a phase I/II clinical trial.

Published in:

Bone Marrow Transplantation, 2008, v. 41, n. 9, p. 771, doi. 10.1038/sj.bmt.1705979

By:

De Lima, M.;
McMannis, J.;
Gee, A.;
Komanduri, K.;
Couriel, D.;
Andersson, B. S.;
Hosing, C.;
Khouri, I.;
Jones, R.;
Champlin, R.;
Karandish, S.;
Sadeghi, T.;
Peled, T.;
Grynspan, F.;
Daniely, Y.;
Nagler, A.;
Shpall, E. J.

Publication type:

Article

Effect of hematopoietic growth factors on severity of experimental autoimmune encephalomyelitis.

Published in:

Bone Marrow Transplantation, 2006, v. 38, n. 6, p. 453, doi. 10.1038/sj.bmt.1705473

By:

Verda, L.;
Luo, K.;
Kim, D.-A.;
Bronesky, D.;
Kohm, A. P.;
Miller, S. D.;
Statkute, L.;
Oyama, Y.;
Burt, R. K.

Publication type:

Article

Prolonged thrombocytopenia after allogeneic hematopoietic stem cell transplantation: associations with impaired platelet production and increased platelet turnover.

Published in:

Bone Marrow Transplantation, 2006, v. 38, n. 5, p. 377, doi. 10.1038/sj.bmt.1705444

By:

Yamazaki, R.;
Kuwana, M.;
Mori, T.;
Okazaki, Y.;
Kawakami, Y.;
Ikeda, Y.;
Okamoto, S.

Publication type:

Article

Superior ex vivo cord blood expansion following co-culture with bone marrow-derived mesenchymal stem cells.

Published in:

Bone Marrow Transplantation, 2006, v. 37, n. 4, p. 359, doi. 10.1038/sj.bmt.1705258

By:

Robinson, S N.;
Ng, J;
Niu, T;
Yang, H;
McMannis, J D;
Karandish, S;
Kaur, I;
Fu, P;
Del Angel, M;
Messinger, R;
Flagge, F;
de Lima, M;
Decker, W;
Xing, D;
Champlin, R;
Shpall, E J

Publication type:

Article

Two candidate genes for low platelet count identified in an Asian Indian kindred by genome-wide linkage analysis: glycoprotein IX and thrombopoietin.

Published in:

European Journal of Human Genetics, 2006, v. 14, n. 1, p. 101, doi. 10.1038/sj.ejhg.5201499

By:

Garner, Chad;
Best, Steve;
Menzel, Stephan;
Rooks, Helen;
Spector, Tim D.;
Thein, Swee Lay

Publication type:

Article

Multivariate QTL linkage analysis suggests a QTL for platelet count on chromosome 19q.

Published in:

European Journal of Human Genetics, 2004, v. 12, n. 10, p. 835, doi. 10.1038/sj.ejhg.5201248

By:

Evans, David M;
Zhu, Gu;
Duffy, David L;
Montgomery, Grant W;
Frazer, Ian H;
Martin, Nicholas G

Publication type:

Article

Regeneration-associated cells improve recovery from myocardial infarction through enhanced vasculogenesis, anti-inflammation, and cardiomyogenesis.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0203244

By:

Salybekov, Amankeldi A.;
Kawaguchi, Akira T.;
Masuda, Haruchika;
Vorateera, Kosit;
Okada, Chisa;
Asahara, Takayuki

Publication type:

Article

Immature platelet fraction and thrombopoietin in patients with liver cirrhosis: A cohort study.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0192271

By:

Rauber, Philip;
Lammert, Frank;
Grotemeyer, Katharina;
Appenrodt, Beate

Publication type:

Article

Human mass balance, metabolism, and cytochrome P450 phenotyping of lusutrombopag.

Published in:

Xenobiotica, 2021, v. 51, n. 3, p. 287, doi. 10.1080/00498254.2020.1845416

By:

Kawachi, Tomoyuki;
Ninomiya, Mizuki;
Katsube, Takayuki;
Wajima, Toshihiro;
Kanazu, Takushi

Publication type:

Article

Megakaryothrombopoiesis During Ex Vivo Expansion of Human Cord Blood CD34+ Cells Using Thrombopoietin.

Published in:

Scandinavian Journal of Immunology, 2002, v. 55, n. 1, p. 88, doi. 10.1046/j.1365-3083.2002.01031.x

By:

Woo, S;
Kie, J;
Ryu, K;
Moon, H;
Chung, W;
Hwang, D;
Kim, S;
Han, T;
Hahn, M;
Chong, Y;
Park, H;
Seoh, J

Publication type:

Article

Aging platelets stimulate TPO production.

Published in:

Nature Medicine, 2015, v. 21, n. 1, p. 11, doi. 10.1038/nm.3780

By:

Kile, Benjamin T

Publication type:

Article

Boosting platelet production.

Published in:

Nature Medicine, 2008, v. 14, n. 9, p. 917, doi. 10.1038/nm0908-917

By:

Wei, Andrew;
Jackson, Shaun P.

Publication type:

Article

Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes.

Published in:

Nature Medicine, 2006, v. 12, n. 5, p. 557, doi. 10.1038/nm1400

By:

Jin, David K.;
Shido, Koji;
Kopp, Hans-Georg;
Petit, Isabelle;
Shmelkov, Sergey V.;
Young, Lauren M.;
Hooper, Andrea T.;
Amano, Hideki;
Avecilla, Scott T.;
Heissig, Beate;
Hattori, Koichi;
Zhang, Fan;
Hicklin, Daniel J.;
Wu, Yan;
Zhu, Zhenping;
Dunn, Ashley;
Salari, Hassan;
Werb, Zena;
Hackett, Neil R.;
Crystal, Ronald G.

Publication type:

Article

Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies.

Published in:

Nature Genetics, 2015, v. 47, n. 10, p. 1131, doi. 10.1038/ng.3380

By:

Saliba, Joseph;
Saint-Martin, Cécile;
Di Stefano, Antonio;
Lenglet, Gaëlle;
Marty, Caroline;
Pasquier, Florence;
Valle, Véronique Della;
Secardin, Lise;
Mahfoudhi, Emna;
Grosjean, Sarah;
Droin, Nathalie;
Diop, M'boyba;
Dessen, Philippe;
Palazzo, Alberta;
Merlevede, Jane;
Isnard, Françoise;
Casadevall, Nicole;
Solary, Eric;
Debili, Najet;
Bernard, Olivier A

Publication type:

Article

The effect of recombinant human thrombopoietin (rhTPO) on sepsis patients with acute severe thrombocytopenia: a study protocol for a multicentre randomised controlled trial (RESCUE trial).

Published in:

2019

By:

Zhou, Zhigang;
Feng, Tienan;
Xie, Yun;
Huang, Peijie;
Xie, Hui;
Tian, Rui;
Qian, Biyun;
Wang, Ruilan

Publication type:

journal article

Differences in the haematological profile of healthy70 year old men and women: normal ranges withconfirmatory factor analysis.

Published in:

BMC Blood Disorders, 2010, v. 10, p. 4

By:

McIlhagger, Rowan;
Gow, Alan J.;
Brett, Caroline E.;
Corley, Janie;
Taylor, Michelle;
Deary, Ian J.;
Starr, John M.

Publication type:

Article

Plasma thrombopoietin levels in liver cirrhosis and kidney failure.

Published in:

1999

By:

Stockelberg, D.;
Andersson, P.-O.;
Björnsson, E.;
Björk, S.;
Wadenvik, H.;
Andersson, P;
Björnsson, E;
Björk, S

Publication type:

journal article

Thrombopoietin protects against doxorubicin-induced cardiomyopathy, improves cardiac function, and reversely alters specific signalling networks.

Published in:

European Journal of Heart Failure, 2011, v. 13, n. 4, p. 366, doi. 10.1093/eurjhf/hfr001

By:

Chan, Kathy Yuen-Yee;
Xiang, Ping;
Zhou, Ligang;
Li, Karen;
Ng, Pak-Cheung;
Wang, Chi-Chiu;
Zhang, Lei;
Deng, Hai-Yan;
Pong, Nga-Hin;
Zhao, Hailu;
Chan, Wood-Yee;
Sung, Rita Yn-Tz

Publication type:

Article

Identification of a new Mpl-interacting protein, Atp5d.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 391, n. 1/2, p. 85, doi. 10.1007/s11010-014-1990-x

By:

Liu, Hongyan;
Zhao, Zhenhu;
Zhong, Yuxu;
Shan, Yajun;
Sun, Xiaohong;
Mao, Bingzhi;
Cong, Yuwen

Publication type:

Article

Oral eltrombopag versus subcutaneous recombinant human thrombopoietin for promoting platelet engraftment after allogeneic stem cell transplantation: A prospective, non‐inferiority, randomized controlled trial.

Published in:

Hematological Oncology, 2022, v. 40, n. 4, p. 777, doi. 10.1002/hon.3017

By:

Wen, Bingbing;
Zhang, Xiaohan;
Chen, Shiyu;
Fan, Jingchao;
Yang, Sitian;
Cai, Yun;
Wang, Pengcheng;
Zhang, Qiaoxia;
Gu, Qingli;
Du, Xin

Publication type:

Article

Efficacy of Recombinant Human Thrombopoietin for the Treatment of Secondary Failure of Platelet Recovery After Allogeneic HSCT.

Published in:

Clinical & Applied Thrombosis/Hemostasis, 2022, v. 28, p. 1, doi. 10.1177/10760296211068037

By:

Cao, Yigeng;
Wang, Mingyang;
Shen, Biao;
Zhao, Fei;
Zhang, Rongli;
Chen, Xin;
He, Yi;
Zhai, Weihua;
Ma, Qiaoling;
Wei, Jialin;
Huang, Yong;
Yang, Donglin;
Pang, Aiming;
Feng, Sizhou;
Jiang, Erlie;
Han, Mingzhe

Publication type:

Article

Eltrombopag Effectiveness and Tolerability in Chronic Immune Thrombocytopenia: A Meta-Analysis.

Published in:

Clinical & Applied Thrombosis/Hemostasis, 2021, v. 27, p. 1, doi. 10.1177/10760296211005555

By:

Ahmed, Hafiz Abdul Waqas;
Masoud, Ahmed Taher;
Han, Jia;
Adel Sofy, Ahmed;
Saeed Ahmed, Ahmed;
Abdesattart, Ahmed Taha;
Drokow, Emmanuel Kwateng;
Sun, Kai

Publication type:

Article

Modeling the Thrombopoietic Effects of Burn.

Published in:

Letters in Biomathematics, 2014, v. 1, n. 1, p. 111, doi. 10.1080/23737867.2014.11414474

By:

Wentz, Jacqueline;
Oldson, Darren;
Stricklin, Daniela

Publication type:

Article

造血干细胞动员: 不同方案的优缺点及预测模型与技术提升.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2025, v. 29, n. 36, p. 7863, doi. 10.12307/2025.553

By:

韩孟君;
许芳

Publication type:

Article

Clinical significance of the changes of platelet counts and serum thrombopoietin levels in chronic hepatitis C patients treated with different doses of consensus interferon

Published in:

Hepatology Research, 2002, v. 24, n. 3, p. 236, doi. 10.1016/S1386-6346(02)00108-0

By:

Chu, Chen-Wei;
Hwang, Shinn-Jang;
Lu, Rei-Hwa;
Lai, Chiung-Ru;
Luo, Jiing-Chyuan;
Wang, Yuan-Jen;
Chang, Full-Young;
Lee, Shou-Dong

Publication type:

Article

Restoration of thrombopoietin production after partial splenic embolization leads to resolution of thrombocytopenia in liver cirrhosis

Published in:

Hepatology Research, 2002, v. 23, n. 4, p. 265, doi. 10.1016/S1386-6346(02)00002-5

By:

Hidaka, Hisashi;
Kokubu, Shigehiro;
Saigenji, Katsunori;
Isobe, Yoshinori;
Maeda, Tadanobu

Publication type:

Article