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- Title
Open-label study of the efficacy and safety of topical treatment with TDT 067 (terbinafine in Transfersome<sup>®</sup>) in patients with onychomycosis.
- Authors
Dominicus, R.; Weidner, C.; Tate, H.; Kroon, H.-A.
- Abstract
The article presents an open-label study which determined the safety and efficacy of topical treatment with terbinafine in Transfersome (TDT 067) in patients with onychomycosis. The researchers assessed the subungual samples at primary endpoints and nail growth using standardized methodology. The study found that efficacy rates are low compared with oral antifungal agents due to the formulations that failed to achieve adequate concentrations of active ingredients at the site of infection.
- Subjects
ANTISEPTICS; ANTIFUNGAL agents; ONYCHOMYCOSIS; TERBINAFINE; DRUG efficacy; PATIENTS
- Publication
British Journal of Dermatology, 2012, Vol 166, Issue 6, p1360
- ISSN
0007-0963
- Publication type
Academic Journal
- DOI
10.1111/j.1365-2133.2011.10766.x