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A phase I study of panobinostat in pediatric patients with refractory solid tumors, including CNS tumors.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation.
- Published in:
- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0284-y
- By:
- Publication type:
- Article
High-resolution MRI demonstrates that more than 90% of small intracranial melanoma metastases develop in close relationship to the leptomeninges.
- Published in:
- Neuro-Oncology, 2020, v. 22, n. 3, p. 423, doi. 10.1093/neuonc/noz171
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- Publication type:
- Article
The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma.
- Published in:
- Science Signaling, 2015, v. 8, n. 390, p. 1, doi. 10.1126/scisignal.aab1111
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- Publication type:
- Article
Cell Division and Hematopoietic Stem Cells.
- Published in:
- Cell Cycle, 2005, v. 4, n. 7, p. 893, doi. 10.4161/cc.4.7.1831
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- Publication type:
- Article
Consensus approaches to best practice management of gastrointestinal stromal tumors.
- Published in:
- Asia Pacific Journal of Clinical Oncology, 2008, v. 4, n. 4, p. 188, doi. 10.1111/j.1743-7563.2008.00218.x
- By:
- Publication type:
- Article
Sunitinib malate in the treatment of renal cell carcinoma and gastrointestinal stromal tumor: Recommendations for patient management.
- Published in:
- Asia Pacific Journal of Clinical Oncology, 2007, v. 3, n. 4, p. 167, doi. 10.1111/j.1743-7563.2007.00136.x
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- Publication type:
- Article
Optimizing Amplification of the GC-Rich TERT Promoter Region Using 7-Deaza-dGTP for Droplet Digital PCR Quantification of TERT Promoter Mutations.
- Published in:
- Clinical Chemistry, 2018, v. 64, n. 4, p. 745, doi. 10.1373/clinchem.2017.284257
- By:
- Publication type:
- Article
Blending space and time to talk about cancer in extended reality.
- Published in:
- NPJ Digital Medicine, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s41746-024-01262-x
- By:
- Publication type:
- Article
Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours.
- Published in:
- Scientific Reports, 2013, p. 1, doi. 10.1038/srep03494
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- Publication type:
- Article
Applications of Positron Emission Tomography in the Development of Molecular Targeted Cancer Therapeutics.
- Published in:
- BioDrugs, 2003, v. 17, n. 5, p. 339, doi. 10.2165/00063030-200317050-00004
- By:
- Publication type:
- Article
Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance.
- Published in:
- International Journal of Cancer, 2018, v. 142, n. 10, p. 2139, doi. 10.1002/ijc.31220
- By:
- Publication type:
- Article
Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model.
- Published in:
- International Journal of Cancer, 2016, v. 139, n. 1, p. 194, doi. 10.1002/ijc.30056
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- Publication type:
- Article
Checkpoint inhibitors in melanoma and early phase development in solid tumors: what's the future?
- Published in:
- 2017
- By:
- Publication type:
- Editorial
Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Harnessing the immunotherapeutic potential of CDK4/6 inhibitors in melanoma: is timing everything?
- Published in:
- NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00273-9
- By:
- Publication type:
- Article
Bevacizumab as a steroid‐sparing agent during immunotherapy for melanoma brain metastases: A case series.
- Published in:
- Health Science Reports, 2019, v. 2, n. 3, p. N.PAG, doi. 10.1002/hsr2.115
- By:
- Publication type:
- Article
UBF levels determine the number of active ribosomal RNA genes in mammals.
- Published in:
- Journal of Cell Biology, 2008, v. 183, n. 7, p. 1259, doi. 10.1083/jcb.200805146
- By:
- Publication type:
- Article
Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. N.PAG, doi. 10.3389/fimmu.2021.661737
- By:
- Publication type:
- Article
Triple Combination Improves PFS in BRAF-Positive Melanoma.
- Published in:
- Journal of Oncology Navigation & Survivorship, 2020, v. 11, n. 7, p. 244
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- Publication type:
- Article
Targeted therapy in the era of immunotherapy.
- Published in:
- Oncology Exchange, 2018, v. 17, n. 4, p. 20
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- Publication type:
- Article
AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer.
- Published in:
- Science Signaling, 2011, v. 4, n. 188, p. 1, doi. 10.1126/scisignal.2001754
- By:
- Publication type:
- Article
Differential <sup>18</sup>F-FDG and 3'-Deoxy-3'-<sup>18</sup>F-Fluorothymidine PET Responses to Pharmacologic Inhibition of the c-MET Receptor in Preclinical Tumor Models.
- Published in:
- Journal of Nuclear Medicine, 2011, v. 52, n. 8, p. 1261, doi. 10.2967/jnumed.110.086967
- By:
- Publication type:
- Article
UF-FLT PET as a Surrogate Marker of Drug Efficacy During mTOR Inhibition by Everolimus in a Preclinical Cisplatin-Resistant Ovarian Tumor Model.
- Published in:
- Journal of Nuclear Medicine, 2010, v. 51, n. 10, p. 1559, doi. 10.2967/jnumed.109.073288
- By:
- Publication type:
- Article
<sup>18</sup>F-FLT PET as a Surrogate Marker of Drug Efficacy During mTOR Inhibition by Everolimus in a Preclinical Cisplatin-Resistant Ovarian Tumor Model.
- Published in:
- Journal of Nuclear Medicine, 2010, v. 51, n. 10, p. 1559, doi. 10.2967/jnumed.109.073288
- By:
- Publication type:
- Article
Impact of initial treatment and prognostic factors on postprogression survival in BRAF-mutated metastatic melanoma treated with dacarbazine or vemurafenib ± cobimetinib: a pooled analysis of four clinical trials.
- Published in:
- 2020
- By:
- Publication type:
- journal article
The Advantages and Challenges of Using FDG PET/CT for Response Assessment in Melanoma in the Era of Targeted Agents and Immunotherapy.
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2017, v. 44, p. 67, doi. 10.1007/s00259-017-3691-7
- By:
- Publication type:
- Article
Dysregulation of the basal RNA polymerase transcription apparatus in cancer.
- Published in:
- 2013
- By:
- Publication type:
- journal article
Dysregulation of the basal RNA polymerase transcription apparatus in cancer.
- Published in:
- Nature Reviews Cancer, 2013, v. 13, n. 5, p. 299, doi. 10.1038/nrc3496
- By:
- Publication type:
- Article
CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci.
- Published in:
- Biomedicines, 2024, v. 13, n. 7, p. 1514, doi. 10.3390/biomedicines12071514
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- Publication type:
- Article
Gene expression profiling of human colon xenograft tumors following treatment with SU11248, a multitargeted tyrosine kinase inhibitor.
- Published in:
- Oncogene, 2004, v. 23, n. 8, p. 1618, doi. 10.1038/sj.onc.1207268
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- Publication type:
- Article
A First-Time-In-Human Phase I Clinical Trial of Bispecific Antibody-Targeted, Paclitaxel-Packaged Bacterial Minicells.
- Published in:
- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0144559
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- Publication type:
- Article
Bioinformatics Pipelines for Targeted Resequencing and Whole-Exome Sequencing of Human and Mouse Genomes: A Virtual Appliance Approach for Instant Deployment.
- Published in:
- PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095217
- By:
- Publication type:
- Article
CDC25B Overexpression Stabilises Centrin 2 and Promotes the Formation of Excess Centriolar Foci.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0067822
- By:
- Publication type:
- Article
Identification of Functional Networks of Estrogen- and c-Myc-Responsive Genes and Their Relationship to Response to Tamoxifen Therapy in Breast Cancer.
- Published in:
- PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0002987
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- Publication type:
- Article
The genomic landscape of phaeochromocytoma.
- Published in:
- Journal of Pathology, 2015, v. 236, n. 1, p. 78, doi. 10.1002/path.4503
- By:
- Publication type:
- Article
Terminal osteoblast differentiation, mediated by runx2 and p27<sup>KIP1</sup> , is disrupted in osteosarcoma.
- Published in:
- Journal of Cell Biology, 2004, v. 167, n. 5, p. 925, doi. 10.1083/jcb.200409187
- By:
- Publication type:
- Article
Towards new models of cancer care in Australia: lessons from Victoria's response to the COVID‐19 pandemic.
- Published in:
- Internal Medicine Journal, 2020, v. 50, n. 10, p. 1282, doi. 10.1111/imj.15012
- By:
- Publication type:
- Article
Acute toxic epidermal necrolysis reaction post single dose pembrolizumab with preceding cephalosporin exposure: successful rechallenge with anti‐PD‐1 therapy.
- Published in:
- 2019
- By:
- Publication type:
- Case Study
Exploring the feasibility and utility of exome‐scale tumour sequencing in a clinical setting.
- Published in:
- Internal Medicine Journal, 2018, v. 48, n. 7, p. 786, doi. 10.1111/imj.13806
- By:
- Publication type:
- Article
Lymphatic and Hematogenous Dissemination in Patients With Primary Cutaneous Melanoma.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Brca1 inactivation induces p27<sup>Kip1</sup>-dependent cell cycle arrest and delayed development in the mouse mammary gland.
- Published in:
- Oncogene, 2004, v. 23, n. 36, p. 6136, doi. 10.1038/sj.onc.1207805
- By:
- Publication type:
- Article
Concordance of somatic mutational profile in multiple primary melanomas.
- Published in:
- Pigment Cell & Melanoma Research, 2018, v. 31, n. 5, p. 592, doi. 10.1111/pcmr.12702
- By:
- Publication type:
- Article
Association of programmed death ligand‐1 (PD‐L1) expression with treatment outcomes in patients with BRAF mutation‐positive melanoma treated with vemurafenib or cobimetinib combined with vemurafenib.
- Published in:
- Pigment Cell & Melanoma Research, 2018, v. 31, n. 4, p. 516, doi. 10.1111/pcmr.12670
- By:
- Publication type:
- Article
Clinicopathological characteristics associated with BRAF<sup>K601E</sup> and BRAF<sup>L597</sup> mutations in melanoma.
- Published in:
- Pigment Cell & Melanoma Research, 2016, v. 29, n. 2, p. 222, doi. 10.1111/pcmr.12450
- By:
- Publication type:
- Article
Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma.
- Published in:
- Pigment Cell & Melanoma Research, 2014, v. 27, n. 6, p. 1117, doi. 10.1111/pcmr.12295
- By:
- Publication type:
- Article
Control of NF- kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I- BET151.
- Published in:
- Pigment Cell & Melanoma Research, 2014, v. 27, n. 6, p. 1126, doi. 10.1111/pcmr.12282
- By:
- Publication type:
- Article
Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines.
- Published in:
- Pigment Cell & Melanoma Research, 2014, v. 27, n. 4, p. 590, doi. 10.1111/pcmr.12228
- By:
- Publication type:
- Article
Clinical outcome and pathological features associated with NRAS mutation in cutaneous melanoma.
- Published in:
- Pigment Cell & Melanoma Research, 2011, v. 24, n. 4, p. 666, doi. 10.1111/j.1755-148X.2011.00873.x
- By:
- Publication type:
- Article
Mutations in KIT occur at low frequency in melanomas arising from anatomical sites associated with chronic and intermittent sun exposure.
- Published in:
- Pigment Cell & Melanoma Research, 2010, v. 23, n. 2, p. 210, doi. 10.1111/j.1755-148X.2010.00671.x
- By:
- Publication type:
- Article