Granulomatous cutaneous T‐cell lymphoma: a diagnostic challenge.

Hutchison, Eliza; Eraifej, Natalie; Milne, James; Mondaca, Camila; Wainman, Hannah

This article discusses a case of granulomatous cutaneous T-cell lymphoma (G-CTCL), specifically focusing on the diagnostic challenges associated with this condition. The patient, a 46-year-old woman with obesity and irritable bowel syndrome, presented with pruritic red patches and plaques in various areas of her body. The initial differentials included tinea and cellulitis, and the patient underwent various treatments before being speculatively diagnosed with G-CTCL. The article highlights the histopathological similarities and differences between granulomatous mycosis fungoides (GMF) and granulomatous slack skin (GSS), which are subtypes of G-CTCL. The case emphasizes the importance of repeated histopathological assessment in cases of diagnostic uncertainty or poor therapeutic response.

CUTANEOUS T-cell lymphoma; MYCOSIS fungoides; MULTINUCLEATED giant cells; T-cell receptor genes

International Journal of Dermatology, 2024, Vol 63, Issue 8, p1091

0011-9059

Academic Journal

10.1111/ijd.17160