Works matching DE "DIHYDROOROTATE dehydrogenase"
Results: 180
Design and tests of prospective property predictions for novel antimalarial 2-aminopropylaminoquinolones.
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- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 11, p. 1117, doi. 10.1007/s10822-020-00333-x
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- Article
Identification of fungal dihydrouracil-oxidase genes by expression in Saccharomyces cerevisiae.
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- Antonie van Leeuwenhoek, 2022, v. 115, n. 11, p. 1363, doi. 10.1007/s10482-022-01779-9
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- Article
Peripheral Membrane Proteins: Promising Therapeutic Targets across Domains of Life.
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- Membranes, 2021, v. 11, n. 5, p. 346, doi. 10.3390/membranes11050346
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- Article
Tridentate xanthene-based hydrazone ligands and their mononuclear transition metal complexes: synthesis, anti-malarial, antimicrobial and molecular docking studies.
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- Research on Chemical Intermediates, 2024, v. 50, n. 3, p. 1409, doi. 10.1007/s11164-023-05222-0
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- Article
An efficient synthesis of rearranged new biologically active benzimidazoles derived from 2-formyl carvacrol.
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- Research on Chemical Intermediates, 2022, v. 48, n. 1, p. 401, doi. 10.1007/s11164-021-04601-9
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- Article
Lysyl oxidase-like 3 restrains mitochondrial ferroptosis to promote liver cancer chemoresistance by stabilizing dihydroorotate dehydrogenase.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38753-6
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- Article
SYNTHESIS OF A NOVEL CHALCONE DERIVATIVE FROM MYRISTICIN FOR SKIN CANCER PREVENTIVE ACTIVITY.
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- Rasayan Journal of Chemistry, 2021, v. 14, n. 3, p. 1493, doi. 10.31788/RJC.2021.1436312
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- Article
Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target.
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- Genes, 2020, v. 11, n. 12, p. 1468, doi. 10.3390/genes11121468
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- Article
Teriflunomide-induced Palmoplantar Lichenoid Eruption: A Case Report.
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- Acta Dermato-Venereologica, 2024, v. 104, p. 1, doi. 10.2340/actadv.v104.40967
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- Article
Teriflunomide for the treatment of relapsing-remitting multiple sclerosis: patient preference and adherence.
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- Patient Preference & Adherence, 2015, v. 9, p. 265, doi. 10.2147/PPA.S61651
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- Article
New Insights into the Interaction of Class II Dihydroorotate Dehydrogenases with Ubiquinone in Lipid Bilayers as a Function of Lipid Composition.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2437, doi. 10.3390/ijms23052437
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- Article
Teriflunomide Preserves Neuronal Activity and Protects Mitochondria in Brain Slices Exposed to Oxidative Stress.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1538, doi. 10.3390/ijms23031538
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- Article
Identification of 3,4-Dihydro-2 H ,6 H -pyrimido[1,2- c ][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 7236, doi. 10.3390/ijms22137236
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- Article
The mononuclear metal center of type-I dihydroorotase from aquifex aeolicus.
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- BMC Biochemistry, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2091-14-36
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- Article
Teriflunomide treatment exacerbates cardiac ischemia reperfusion injury in isolated rat hearts.
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- Cardiovascular Drugs & Therapy, 2023, v. 37, n. 5, p. 1021, doi. 10.1007/s10557-022-07341-z
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- Article
Madurella mycetomatis, the main causative agent of eumycetoma, is highly susceptible to olorofim.
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- 2020
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- journal article
Dihydroorotate dehydrogenase inhibitor olorofim exhibits promising activity against all clinically relevant species within Aspergillus section Terrei.
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- 2018
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- journal article
Dihydroorotate dehydrogenase inhibitor F901318 has potent in vitro activity against Scedosporium species and Lomentospora prolificans.
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- 2017
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- journal article
Mom Controls the Thermostat: Mitochondria Influence the Neuronal Firing Set Point.
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- Epilepsy Currents, 2019, v. 19, n. 5, p. 336, doi. 10.1177/1535759719868181
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- Article
A double‐blind, randomized, placebo‐controlled phase 2 trial evaluating the selective dihydroorotate dehydrogenase inhibitor vidofludimus calcium in relapsing‐remitting multiple sclerosis.
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- Annals of Clinical & Translational Neurology, 2022, v. 9, n. 7, p. 977, doi. 10.1002/acn3.51574
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- Article
Teriflunomide induces a tolerogenic bias in blood immune cells of MS patients.
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- Annals of Clinical & Translational Neurology, 2019, v. 6, n. 2, p. 355, doi. 10.1002/acn3.711
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- Article
An In Silico Study of the Interactions of Alkaloids from Cryptolepis sanguinolenta with Plasmodium falciparum Dihydrofolate Reductase and Dihydroorotate Dehydrogenase.
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- Journal of Chemistry, 2022, p. 1, doi. 10.1155/2022/5314179
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- Article
Editorial: Metabolic Rewiring in Leukemias.
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- 2021
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- Editorial
Targeting Pyrimidine Metabolism in the Era of Precision Cancer Medicine.
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- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.684961
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- Article
Teriflunomide: Pediatric First Approval.
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- Pediatric Drugs, 2021, v. 23, n. 6, p. 609, doi. 10.1007/s40272-021-00471-1
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- Article
Exploring the Venom Gland Transcriptome of Bothrops asper and Bothrops jararaca : De Novo Assembly and Analysis of Novel Toxic Proteins.
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- Toxins, 2024, v. 16, n. 12, p. 511, doi. 10.3390/toxins16120511
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- Article
Computer-aided discovery of novel SmDHODH inhibitors for schistosomiasis therapy: Ligand-based drug design, molecular docking, molecular dynamic simulations, drug-likeness, and ADMET studies.
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- PLoS Neglected Tropical Diseases, 2024, v. 18, n. 9, p. 1, doi. 10.1371/journal.pntd.0012453
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- Article
The Emerging Role of Ferroptosis in Sepsis.
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- 2022
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- Literature Review
5-aminoimidazole-4-carboxamide ribonucleoside induces differentiation in a subset of primary acute myeloid leukemia blasts.
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- 2020
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- Publication type:
- journal article
IN-SILICO MOLECULAR DOCKING AND ADME EVALUATION OF FICUS RACEMOSA PHYTOCONSTITUENTS TARGETING GLUCOKINASE AND DIHYDROOROTATE DEHYDROGENASE FOR DIABETES MANAGEMENT.
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- Biochemical & Cellular Archives, 2024, p. 3477, doi. 10.51470/bca.2024.24.1-S.3477
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- Article
Phytophthora infestans Dihydroorotate Dehydrogenase Is a Potential Target for Chemical Control – A Comparison With the Enzyme From Solanum tuberosum.
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- Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.01479
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- Article
Cloning and Characterization of Yak DHODH Gene and Its Functional Studies in a Bisphenol S-Induced Ferroptosis Model of Fetal Fibroblasts.
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- Animals (2076-2615), 2023, v. 13, n. 24, p. 3832, doi. 10.3390/ani13243832
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- Article
Correction: Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.
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- 2024
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- Correction Notice
Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase.
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- Veterinary Research, 2023, v. 54, n. 1, p. 1, doi. 10.1186/s13567-023-01251-0
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- Article
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03441-3
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- Article
Inhibition of pyrimidine biosynthesis by strobilurin derivatives induces differentiation of acute myeloid leukemia cells.
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- Leukemia & Lymphoma, 2022, v. 63, n. 5, p. 1202, doi. 10.1080/10428194.2021.2008382
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- Article
Targeting mitochondrial metabolism in acute myeloid leukemia.
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- Leukemia & Lymphoma, 2022, v. 63, n. 3, p. 530, doi. 10.1080/10428194.2021.1992759
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- Article
Molecular docking, molecular dynamics simulation, and in vitro evaluation of hydroxythioxanthone derivatives as antimalarial agents.
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- Thai Journal of Pharmaceutical Sciences, 2024, v. 48, n. 4, p. 1
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- Article
Untargeted LC–MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase.
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- Metabolomics, 2019, v. 15, n. 4, p. N.PAG, doi. 10.1007/s11306-019-1520-7
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- Article
Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome.
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- Nucleosides, Nucleotides & Nucleic Acids, 2022, v. 41, n. 12, p. 1337, doi. 10.1080/15257770.2022.2039393
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- Article
Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome.
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- Nucleosides, Nucleotides & Nucleic Acids, 2022, v. 41, n. 12, p. 1318, doi. 10.1080/15257770.2021.2023749
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- Article
The pathway to pyrimidines: The essential focus on dihydroorotate dehydrogenase, the mitochondrial enzyme coupled to the respiratory chain.
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- Nucleosides, Nucleotides & Nucleic Acids, 2020, v. 39, n. 10-12, p. 1281, doi. 10.1080/15257770.2020.1723625
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- Article
Preparation of human dihydroorotate dehydrogenase for interaction studies with lipid bilayers.
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- Nucleosides, Nucleotides & Nucleic Acids, 2020, v. 39, n. 10-12, p. 1306, doi. 10.1080/15257770.2019.1708100
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- Article
Re-evaluation of Brequinar sodium, a dihydroorotate dehydrogenase inhibitor.
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- Nucleosides, Nucleotides & Nucleic Acids, 2018, v. 37, n. 12, p. 666, doi. 10.1080/15257770.2018.1508692
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- Article
Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
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- Nucleosides, Nucleotides & Nucleic Acids, 2018, v. 37, n. 6, p. 329, doi. 10.1080/15257770.2018.1460479
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- Article
Discovery of potential natural dihydroorotate dehydrogenase inhibitors and their synergism with brequinar via integrated molecular docking, dynamic simulations and in vitro approach.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-23006-1
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- Article
Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15520-z
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- Article
Teriflunomide shifts the astrocytic bioenergetic profile from oxidative metabolism to glycolysis and attenuates TNFα-induced inflammatory responses.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07024-7
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- Article
Metabolic Plasticity of Glioblastoma Cells in Response to DHODH Inhibitor BAY2402234 Treatment.
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- Metabolites (2218-1989), 2024, v. 14, n. 8, p. 413, doi. 10.3390/metabo14080413
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- Article
Exploring Thermal Sensitivities and Adaptations of Oxidative Phosphorylation Pathways.
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- Metabolites (2218-1989), 2022, v. 12, n. 4, p. N.PAG, doi. 10.3390/metabo12040360
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- Article