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Title

Phycosaccharide AI, a mixture of alginate polysaccharides, increases stem cell proliferation in aged keratinocytes.

Authors

Charruyer, Alexandra; Fong, Stephen; Yue, Lili; Arron, Sarah T.; Ghadially, Ruby

Abstract

The article presents a study that explores the effects of the naturally occurring alginate polysaccharides on the proliferation of keratinocyte stem cells (SCs) in older population. It mentions the use of holoclone assay in assessing the SC frequency and the self-renewal of phycosaccharide-treated aged human keratinocytes. Results of the study indicate the possible manipulation of SC divisions using the naturally occurring agents for the treatment of wounds and ageing.

Subjects

ALGINATES; MICROBIAL polysaccharides; KERATINOCYTES; STEM cells; WOUND care; CELL proliferation

Publication

Experimental Dermatology, 2016, Vol 25, Issue 9, p738

ISSN

0906-6705

Publication type

Academic Journal

DOI

10.1111/exd.13051

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