Works matching DE "SYNUCLEINS"
Results: 842
Targeting toxic forms of α-synuclein with immunotherapy could alter the progression of Parkinson's disease.
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- Drugs & Therapy Perspectives, 2022, v. 38, n. 11, p. 467, doi. 10.1007/s40267-022-00950-6
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- Article
Genetics of synucleins in neurodegenerative diseases.
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- Acta Neuropathologica, 2021, v. 141, n. 4, p. 471, doi. 10.1007/s00401-020-02202-1
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- Article
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines.
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- Acta Neuropathologica, 2019, v. 137, n. 3, p. 437, doi. 10.1007/s00401-019-01959-4
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- Article
Regional levels of physiological α-synuclein are directly associated with Lewy body pathology.
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- 2018
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- Publication type:
- Letter
Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long term.
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- Acta Neuropathologica, 2018, v. 135, n. 1, p. 65, doi. 10.1007/s00401-017-1792-9
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- Article
Alpha-synuclein oligomers: a new hope.
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- Acta Neuropathologica, 2017, v. 134, n. 6, p. 819, doi. 10.1007/s00401-017-1755-1
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- Article
α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading.
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- Acta Neuropathologica, 2017, v. 134, n. 5, p. 789, doi. 10.1007/s00401-017-1746-2
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- Article
The importance of developing strain-specific models of neurodegenerative disease.
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- 2017
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- Publication type:
- Letter
α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca homeostasis and mitochondrial ATP production.
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- Acta Neuropathologica, 2017, v. 134, n. 1, p. 129, doi. 10.1007/s00401-017-1704-z
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- Article
Histones facilitate α-synuclein aggregation during neuronal apoptosis.
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- Acta Neuropathologica, 2017, v. 133, n. 4, p. 547, doi. 10.1007/s00401-016-1660-z
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- Article
Dermal phospho-alpha-synuclein deposits confirm REM sleep behaviour disorder as prodromal Parkinson's disease.
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- Acta Neuropathologica, 2017, v. 133, n. 4, p. 535, doi. 10.1007/s00401-017-1684-z
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- Article
Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections.
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- Acta Neuropathologica, 2017, v. 133, n. 3, p. 381, doi. 10.1007/s00401-016-1661-y
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- Article
Mesenchymal stem cells enhance α-synuclein clearance via M2 microglia polarization in experimental and human parkinsonian disorder.
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- Acta Neuropathologica, 2016, v. 132, n. 5, p. 685, doi. 10.1007/s00401-016-1605-6
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- Article
α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy.
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- Acta Neuropathologica, 2016, v. 132, n. 1, p. 59, doi. 10.1007/s00401-016-1572-y
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- Publication type:
- Article
Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons.
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- Acta Neuropathologica, 2016, v. 132, n. 1, p. 77, doi. 10.1007/s00401-016-1542-4
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- Publication type:
- Article
Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology.
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- Acta Neuropathologica, 2016, v. 131, n. 3, p. 393, doi. 10.1007/s00401-015-1526-9
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- Article
Non-prion-type transmission in A53T α-synuclein transgenic mice: a normal component of spinal homogenates from naïve non-transgenic mice induces robust α-synuclein pathology.
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- 2016
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- Publication type:
- Letter
Screening for α-synuclein immunoreactive neuronal inclusions in the hippocampus allows identification of atypical MSA (FTLD-synuclein).
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- 2015
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- Publication type:
- Letter
Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation.
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- Acta Neuropathologica, 2015, v. 129, n. 5, p. 695, doi. 10.1007/s00401-015-1408-1
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- Article
Erratum to: Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.
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- 2014
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- Publication type:
- Erratum
In vivo markers of Parkinson's disease and dementia with Lewy bodies: current value of the 5G4 α-synuclein antibody.
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- 2014
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- Publication type:
- Letter
Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.
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- Acta Neuropathologica, 2014, v. 127, n. 5, p. 645, doi. 10.1007/s00401-014-1268-0
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- Publication type:
- Article
Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson's disease.
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- Acta Neuropathologica, 2014, v. 127, n. 2, p. 235, doi. 10.1007/s00401-013-1214-6
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- Article
Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice.
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- Acta Neuropathologica, 2013, v. 126, n. 4, p. 555, doi. 10.1007/s00401-013-1160-3
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- Article
Sequence variants in eukaryotic translation initiation factor 4-gamma (eIF4G1) are associated with Lewy body dementia.
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- Acta Neuropathologica, 2013, v. 125, n. 3, p. 425, doi. 10.1007/s00401-012-1059-4
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- Article
The genetics and neuropathology of Parkinson's disease.
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- Acta Neuropathologica, 2012, v. 124, n. 3, p. 325, doi. 10.1007/s00401-012-1013-5
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- Article
Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.
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- Acta Neuropathologica, 2012, v. 124, n. 1, p. 51, doi. 10.1007/s00401-012-0977-5
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- Article
Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity.
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- Acta Neuropathologica, 2012, v. 123, n. 5, p. 653, doi. 10.1007/s00401-012-0963-y
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- Article
Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons.
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- Acta Neuropathologica, 2012, v. 123, n. 5, p. 671, doi. 10.1007/s00401-011-0926-8
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- Article
Structure of the toxic core of α-synuclein from invisible crystals.
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- Nature, 2015, v. 525, n. 7570, p. 486, doi. 10.1038/nature15368
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- Article
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration.
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- Nature, 2015, v. 522, n. 7556, p. 340, doi. 10.1038/nature14547
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- Article
Neurobiology: Protecting neurons from Parkinson's.
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- Nature, 2013, v. 501, n. 7465, p. 9, doi. 10.1038/501009b
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- Article
Properties of native brain α-synuclein.
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- Nature, 2013, v. 498, n. 7453, p. E4, doi. 10.1038/nature12125
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- Article
Bartels & Selkoe reply.
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- Nature, 2013, v. 498, n. 7453, p. E6, doi. 10.1038/nature12126
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- Article
Parkinson's Disease Biomarkers: Resources for Discovery and Validation.
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- Neuropsychopharmacology, 2014, v. 39, n. 1, p. 241, doi. 10.1038/npp.2013.246
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- Article
Beyond the SNA RE: Munc18-1 chaperones α-synuclein.
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- Journal of Cell Biology, 2016, v. 214, n. 6, p. 641, doi. 10.1083/jcb.201608060
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- Article
LncRNA-UCA1 promotes PD development by upregulating SNCA.
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- European Review for Medical & Pharmacological Sciences, 2018, v. 22, n. 22, p. 7908
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- Article
Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01242-2
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- Article
Synuclein Proteins in Cancer Development and Progression.
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- Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 980, doi. 10.3390/biom13060980
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- Article
Age-Related Changes of the Synucleins Profile in the Mouse Retina.
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- Biomolecules (2218-273X), 2023, v. 13, n. 1, p. 180, doi. 10.3390/biom13010180
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- Article
Intragenic β-synuclein rearrangements in malignancy.
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- Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1167143
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- Article
Pre-aggregation kinetics and intermediates of α-synuclein monitored by the ESIPT probe 7MFE.
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- European Biophysics Journal, 2018, v. 47, n. 4, p. 345, doi. 10.1007/s00249-017-1272-0
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- Publication type:
- Article
Relation of Enteric α-Synuclein to Gastrointestinal Dysfunction in Patients With Parkinson's Disease and in Neurologically Intact Subjects.
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- Journal of Neurogastroenterology & Motility, 2018, v. 24, n. 3, p. 469, doi. 10.5056/jnm17141
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- Publication type:
- Article
Iron Deposition Leads to Neuronal α-Synuclein Pathology by Inducing Autophagy Dysfunction.
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- Frontiers in Neurology, 2017, v. 7/8, p. 1, doi. 10.3389/fneur.2017.00001
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- Article
SNCA Is a Functionally Low-Expressed Gene in Lung Adenocarcinoma.
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- Genes, 2018, v. 9, n. 1, p. 16, doi. 10.3390/genes9010016
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- Article
Mitochondria and α-Synuclein: Friends or Foes in the Pathogenesis of Parkinson's Disease?
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- Genes, 2017, v. 8, n. 12, p. 377, doi. 10.3390/genes8120377
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- Publication type:
- Article
A Dual GLP-1/GIP Receptor Agonist Is More Effective than Liraglutide in the A53T Mouse Model of Parkinson's Disease.
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- Parkinson's Disease (20420080), 2023, p. 1, doi. 10.1155/2023/7427136
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- Article
Mercury and Parkinson's Disease: Promising Leads, but Research Is Needed.
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- Parkinson's Disease (20420080), 2023, p. 1, doi. 10.1155/2023/4709322
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- Publication type:
- Article
Dyrk1a Phosphorylation of α-Synuclein Mediating Apoptosis of Dopaminergic Neurons in Parkinson's Disease.
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- Parkinson's Disease (20420080), 2023, p. 1, doi. 10.1155/2023/8848642
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- Publication type:
- Article
Copper(II) and the pathological H50Q α-synuclein mutant: Environment meets genetics.
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- Communicative & Integrative Biology, 2017, v. 10, n. 1, p. N.PAG, doi. 10.1080/19420889.2016.1270484
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- Publication type:
- Article