Works matching IS 00071188 AND DT 2020 AND VI 177 AND IP 8

Results: 20

The role of mitochondrial dynamics in cardiovascular diseases.
Published in:
2020
By:
- Forte, Maurizio;
- Schirone, Leonardo;
- Ameri, Pietro;
- Basso, Cristina;
- Catalucci, Daniele;
- Modica, Jessica;
- Chimenti, Cristina;
- Crotti, Lia;
- Frati, Giacomo;
- Rubattu, Speranza;
- Schiattarella, Gabriele Giacomo;
- Torella, Daniele;
- Perrino, Cinzia;
- Indolfi, Ciro;
- Sciarretta, Sebastiano;
- Italian Society of Cardiology (SIC) Working group on Cellular and Molecular Biology of the Heart;
- Italian Society of Cardiology Working group on Cellular and Molecular Biology of the Heart
Publication type:
journal article
Evaluation of the profiles of CB1 cannabinoid receptor signalling bias using joint kinetic modelling.
Published in:
2020
By:
- Zhu, Xiao;
- Finlay, David B;
- Glass, Michelle;
- Duffull, Stephen B
Publication type:
journal article
Exploring occupancy of the histamine H3 receptor by pitolisant in humans using PET.
Published in:
2020
By:
- Rusjan, P M;
- Sabioni, P;
- Di Ciano, P;
- Mansouri, E;
- Boileau, I;
- Laveillé, A;
- Capet, M;
- Duvauchelle, T;
- Schwartz, J C;
- Robert, P;
- Le Foll, B;
- Rusjan, Pablo;
- Sabioni, Pamela;
- Di Ciano, Patricia;
- Mansouri, Esmaeil;
- Boileau, Isabelle;
- Laveillé, Alexia;
- Capet, Marc;
- Duvauchelle, Thierry;
- Schwartz, Jean-Charles
Publication type:
journal article
An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.
Published in:
2020
By:
- Lu, Weisheng;
- Tian, Hong;
- Qian, Peng;
- Li, Ying;
- Wang, Yongkang;
- Ge, Yang;
- Sai, Wenbo;
- Gao, Xiangdong;
- Yao, Wenbing
Publication type:
journal article
Proteolysis-targeting chimeras in drug development: A safety perspective.
Published in:
2020
By:
- Moreau, Kevin;
- Coen, Muireann;
- Zhang, Andrew X.;
- Pachl, Fiona;
- Castaldi, M. Paola;
- Dahl, Goran;
- Boyd, Helen;
- Scott, Clay;
- Newham, Pete
Publication type:
journal article
IL-11 in cardiac and renal fibrosis: Late to the party but a central player.
Published in:
2020
By:
- Corden, Benjamin;
- Adami, Eleonora;
- Sweeney, Mark;
- Schafer, Sebastian;
- Cook, Stuart A.
Publication type:
journal article
Negative allosteric modulators of the human calcium-sensing receptor bind to overlapping and distinct sites within the 7-transmembrane domain.
Published in:
2020
By:
- Josephs, Tracy M.;
- Keller, Andrew N.;
- Khajehali, Elham;
- DeBono, Aaron;
- Langmead, Christopher J.;
- Conigrave, Arthur D.;
- Capuano, Ben;
- Kufareva, Irina;
- Gregory, Karen J.;
- Leach, Katie
Publication type:
journal article
Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.
Published in:
2020
By:
- Kuschak, Markus;
- Namasivayam, Vigneshwaran;
- Rafehi, Muhammad;
- Voss, Jan H.;
- Garg, Jaspal;
- Schlegel, Jonathan G.;
- Abdelrahman, Aliaa;
- Kehraus, Stefan;
- Reher, Raphael;
- Küppers, Jim;
- Sylvester, Katharina;
- Hinz, Sonja;
- Matthey, Michaela;
- Wenzel, Daniela;
- Fleischmann, Bernd K.;
- Pfeifer, Alexander;
- Inoue, Asuka;
- Gütschow, Michael;
- König, Gabriele M.;
- Müller, Christa E.
Publication type:
journal article
CD74 knockout protects against LPS-induced myocardial contractile dysfunction through AMPK-Skp2-SUV39H1-mediated demethylation of BCLB.
Published in:
2020
By:
- Luo, Yuanfei;
- Fan, Congcong;
- Yang, Mingjie;
- Dong, Maolong;
- Bucala, Richard;
- Pei, Zhaohui;
- Zhang, Yingmei;
- Ren, Jun
Publication type:
journal article
Different receptor mechanisms underlying phytocannabinoid- versus synthetic cannabinoid-induced tetrad effects: Opposite roles of CB1 /CB2 versus GPR55 receptors.
Published in:
2020
By:
- Wang, Xiao‐Fei;
- Galaj, Ewa;
- Bi, Guo‐Hua;
- Zhang, Cindy;
- He, Yi;
- Zhan, Jia;
- Bauman, Michael H.;
- Gardner, Eliot L.;
- Xi, Zheng‐Xiong;
- Wang, Xiao-Fei;
- Bi, Guo-Hua;
- Xi, Zheng-Xiong
Publication type:
journal article
Identification, preclinical profile, and clinical proof of concept of an orally bioavailable pro-drug of miridesap.
Published in:
2020
By:
- Richards, Duncan;
- Bamford, Mark;
- Liefaard, Lia;
- Haque, Nazneen;
- Lewis, Gareth;
- Storey, Jim;
- Fernando, Disala;
- Kumar, Subramanya;
- Thompson, Douglas;
- Holmes, Duncan S.
Publication type:
journal article
Haemodynamic effects of the flavonoid quercetin in rats revisited.
Published in:
2020
By:
- Vrolijk, Misha F.;
- Essen, Helma;
- Opperhuizen, Antoon;
- Bast, Aalt;
- Janssen, Ben J.;
- van Essen, Helma
Publication type:
journal article
Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
Published in:
2020
By:
- Foo, Chun Shin;
- Jobichen, Chacko;
- Hassan‐Puttaswamy, Varuna;
- Dekan, Zoltan;
- Tae, Han‐Shen;
- Bertrand, Daniel;
- Adams, David J.;
- Alewood, Paul F.;
- Sivaraman, J.;
- Nirthanan, Selvanayagam;
- Kini, R. Manjunatha;
- Hassan-Puttaswamy, Varuna;
- Tae, Han-Shen
Publication type:
journal article
Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-κB pathway in mice.
Published in:
2020
By:
- Wang, Qinyu;
- Ou, Yangjie;
- Hu, Guomin;
- Wen, Cong;
- Yue, Shanshan;
- Chen, Cong;
- Xu, Lu;
- Xie, Jiawei;
- Dai, Hui;
- Xiao, Han;
- Zhang, Youyi;
- Qi, Rong
Publication type:
journal article
Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase.
Published in:
2020
By:
- Liu, Gang;
- Wu, Fuhua;
- Jiang, Xiaoli;
- Que, Yumei;
- Qin, Zhexue;
- Hu, Pingping;
- Lee, Kin Sing Stephen;
- Yang, Jian;
- Zeng, Chunyu;
- Hammock, Bruce D.;
- Tong, Xiaoyong
Publication type:
journal article
Paracetamol is a centrally acting analgesic using mechanisms located in the periaqueductal grey.
Published in:
2020
By:
- Barrière, David André;
- Boumezbeur, Fawzi;
- Dalmann, Romain;
- Cadeddu, Roberto;
- Richard, Damien;
- Pinguet, Jérémy;
- Daulhac, Laurence;
- Sarret, Philippe;
- Whittingstall, Kevin;
- Keller, Matthieu;
- Mériaux, Sébastien;
- Eschalier, Alain;
- Mallet, Christophe
Publication type:
journal article
Butyrate protects against high-fat diet-induced atherosclerosis via up-regulating ABCA1 expression in apolipoprotein E-deficiency mice.
Published in:
2020
By:
- Du, Yu;
- Li, Xingxing;
- Su, Chunyan;
- Xi, Mei;
- Zhang, Xiumin;
- Jiang, Zhibo;
- Wang, Li;
- Hong, Bin
Publication type:
journal article
Novel neuroactive steroid with hypnotic and T‐type calcium channel blocking properties exerts effective analgesia in a rodent model of post‐surgical pain.
Published in:
British Journal of Pharmacology, 2020, v. 177, n. 8, p. 1735, doi. 10.1111/bph.14930
By:
- Joksimovic, Sonja Lj.;
- Joksimovic, Srdjan M.;
- Manzella, Francesca M.;
- Asnake, Betelehem;
- Orestes, Peihan;
- Raol, Yogendra H.;
- Krishnan, Kathiresan;
- Covey, Douglas F.;
- Jevtovic‐Todorovic, Vesna;
- Todorovic, Slobodan M.
Publication type:
Article
Angiotensin-(1-7) mitigated angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E-knockout mice.
Published in:
2020
By:
- Xue, Fei;
- Yang, Jianmin;
- Cheng, Jing;
- Sui, Wenhai;
- Cheng, Cheng;
- Li, Hongxuan;
- Zhang, Meng;
- Zhang, Jie;
- Xu, Xingli;
- Ma, Jing;
- Lu, Lin;
- Xu, Jinfeng;
- Zhang, Yun;
- Zhang, Cheng
Publication type:
journal article
Issue Information.
Published in:
British Journal of Pharmacology, 2020, v. 177, n. 8, p. 1693, doi. 10.1111/bph.14727
Publication type:
Article

Works matching IS 00071188 AND DT 2020 AND VI 177 AND IP 8

The role of mitochondrial dynamics in cardiovascular diseases.

Evaluation of the profiles of CB<sub>1</sub> cannabinoid receptor signalling bias using joint kinetic modelling.

Exploring occupancy of the histamine H<sub>3</sub> receptor by pitolisant in humans using PET.

An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.

Proteolysis-targeting chimeras in drug development: A safety perspective.

IL-11 in cardiac and renal fibrosis: Late to the party but a central player.

Negative allosteric modulators of the human calcium-sensing receptor bind to overlapping and distinct sites within the 7-transmembrane domain.

Cell-permeable high-affinity tracers for G<sub>q</sub> proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

CD74 knockout protects against LPS-induced myocardial contractile dysfunction through AMPK-Skp2-SUV39H1-mediated demethylation of BCLB.

Different receptor mechanisms underlying phytocannabinoid- versus synthetic cannabinoid-induced tetrad effects: Opposite roles of CB<sub>1</sub> /CB<sub>2</sub> versus GPR55 receptors.

Identification, preclinical profile, and clinical proof of concept of an orally bioavailable pro-drug of miridesap.

Haemodynamic effects of the flavonoid quercetin in rats revisited.

Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.

Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-κB pathway in mice.

Inactivation of Cys<sup>674</sup> in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase.

Paracetamol is a centrally acting analgesic using mechanisms located in the periaqueductal grey.

Butyrate protects against high-fat diet-induced atherosclerosis via up-regulating ABCA1 expression in apolipoprotein E-deficiency mice.

Novel neuroactive steroid with hypnotic and T‐type calcium channel blocking properties exerts effective analgesia in a rodent model of post‐surgical pain.

Angiotensin-(1-7) mitigated angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E-knockout mice.

Issue Information.