Works matching DE "GENETICS of Alzheimer's disease"

Results: 859

Evidence of linkage and association on chromosome 20 for late-onset Alzheimer disease.

Published in:

Neurogenetics, 2004, v. 5, n. 2, p. 121, doi. 10.1007/s10048-004-0174-3

By:

Goddard, Katrina A.B.;
Olson, Jane M.;
Payami, Haydeh;
van der Voet, Monique;
Kuivaniemi, Helena;
Tromp, Gerard

Publication type:

Article

Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease.

Published in:

Neurogenetics, 2004, v. 5, n. 2, p. 115, doi. 10.1007/s10048-004-0173-4

By:

Blomqvist, Mia E.-L.;
Silburn, Peter A.;
Buchanan, Daniel D.;
Andreasen, Niels;
Blennow, Kaj;
Pedersen, Nancy L.;
Brookes, Anthony J.;
Mellick, George D.;
Prince, Jonathan A.

Publication type:

Article

Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 6, p. 499, doi. 10.1038/nsmb.2991

By:

Xiao, Yiling;
Ma, Buyong;
McElheny, Dan;
Parthasarathy, Sudhakar;
Long, Fei;
Hoshi, Minako;
Nussinov, Ruth;
Ishii, Yoshitaka

Publication type:

Article

Public knowledge of late-life cognitive decline and dementia in an international sample.

Published in:

Dementia (14713012), 2020, v. 19, n. 6, p. 1758, doi. 10.1177/1471301218805923

By:

Van Patten, Ryan;
Tremont, Geoffrey

Publication type:

Article

"In the flesh": Narratives of family caregivers at risk of Early-onset Familial Alzheimer's Disease.

Published in:

Dementia (14713012), 2020, v. 19, n. 5, p. 1474, doi. 10.1177/1471301218801501

By:

García-Toro, Maritza;
Sánchez-Gómez, María Cruz;
Madrigal Zapata, Lucía;
Lopera, Francisco Javier

Publication type:

Article

SNPing Away at Genome-Wide Disease Association Studies.

Published in:

Bio-IT World, 2007, v. 6, n. 6, p. 28

By:

Glaser, Vicki

Publication type:

Article

BCHE and CYP2D6 genetic variation in Alzheimer's disease patients treated with cholinesterase inhibitors.

Published in:

European Journal of Clinical Pharmacology, 2011, v. 67, n. 11, p. 1147, doi. 10.1007/s00228-011-1064-x

By:

Chianella, Caterina;
Gragnaniello, Daniela;
Maisano Delser, Pierpaolo;
Visentini, Maria;
Sette, Elisabetta;
Tola, Maria;
Barbujani, Guido;
Fuselli, Silvia

Publication type:

Article

Do CYP3A and ABCB1 genotypes influence the plasma concentration and clinical outcome of donepezil treatment?

Published in:

European Journal of Clinical Pharmacology, 2011, v. 67, n. 1, p. 47, doi. 10.1007/s00228-010-0883-5

By:

Magliulo, Laura;
Dahl, Marja-Liisa;
Lombardi, Grazia;
Fallarini, Silvia;
Villa, Laura;
Biolcati, Aldo;
Scordo, Maria

Publication type:

Article

Association Study of the TREM2 Gene and Identification of a Novel Variant in Exon 2 in Iranian Patients with Late-Onset Alzheimer's Disease.

Published in:

Medical Principles & Practice, 2015, v. 24, n. 4, p. 351, doi. 10.1159/000430842

By:

Mehrjoo, Zohreh;
Najmabadi, amin;
abedini, Seyedeh Sedigheh;
Mohseni, Marzieh;
Kamali, Koorosh;
Najmabadi, Hossein;
Khorram Khorshid, Hamid Reza

Publication type:

Article

ZCCHC17 is a master regulator of synaptic gene expression in Alzheimer's disease.

Published in:

Bioinformatics, 2018, v. 34, n. 3, p. 367, doi. 10.1093/bioinformatics/btx608

By:

Tomljanovic, Zeljko;
Patel, Mitesh;
Shin, William;
Califano, Andrea;
Teich, Andrew F

Publication type:

Article

Genome-wide analysis of DNA methylation profiles in a senescence-accelerated mouse prone 8 brain using whole-genome bisulfite sequencing.

Published in:

Bioinformatics, 2017, v. 33, n. 11, p. 1591, doi. 10.1093/bioinformatics/btx040

By:

Shuai Zhang;
Chunxia Qin;
Guoqiong Cao;
Limin Guo;
Chengqiang Feng;
Wensheng Zhang

Publication type:

Article

From phenotype to genotype: an association study of longitudinal phenotypic markers to Alzheimer's disease relevant SNPs.

Published in:

Bioinformatics, 2012, v. 28, n. 18, p. i619

By:

Wang, Hua;
Nie, Feiping;
Huang, Heng;
Yan, Jingwen;
Kim, Sungeun;
Nho, Kwangsik;
Risacher, Shannon L.;
Saykin, Andrew J.;
Shen, Li

Publication type:

Article

Identification of novel missense mutations (c.1156T>C and c.785T>C) in the PSEN1 gene in Chinese families with early-onset Alzheimer's disease.

Published in:

Archives of Medical Science - Aging, 2021, v. 4, n. 1, p. e6, doi. 10.5114/amsa.2021.107802

By:

Lu Ren;
Qiuyan Wang;
Guowen Min;
Yarong Zhao;
Yang Li

Publication type:

Article

THE OBSERVATORY. Alzheimer's disease.

Published in:: Medical Laboratory Observer (MLO), 2018, v. 50, n. 8, p. 9
Publication type:: Article

THE OBSERVATORY. Genetics/Genomics.

Published in:: Medical Laboratory Observer (MLO), 2018, v. 50, n. 2, p. 6
Publication type:: Article

Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study.

Published in:

JAMA Network Open, 2025, v. 8, n. 1, p. e2455571, doi. 10.1001/jamanetworkopen.2024.55571

By:

Oomens, Julie E.;
van Gils, Veerle;
Vos, Stephanie J. B.;
Freeze, Whitney M.;
Maserejian, Nancy N.;
Curiale, Gioacchino;
Gillis, Cai;
Boada, Mercè;
van der Flier, Wiesje M.;
Hort, Jakub;
Johnson, Sterling C.;
Lleó, Alberto;
Ramakers, Inez H.;
Rodrigue, Karen M.;
Sánchez-Juan, Pascual;
Sarazin, Marie;
Scarmeas, Nikolaos;
Zetterberg, Henrik;
Alcolea, Daniel;
Barkhof, Frederik

Publication type:

Article

Overexpression of U1 snRNA induces decrease of U1 spliceosome function associated with Alzheimer’s disease.

Published in:

Journal of Neurogenetics, 2017, v. 31, n. 4, p. 337, doi. 10.1080/01677063.2017.1395425

By:

Cheng, Zhi;
Shang, Yingchun;
Gao, Shan;
Zhang, Tao

Publication type:

Article

CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease?

Published in:

Annals of Clinical & Translational Neurology, 2015, v. 2, n. 2, p. 131, doi. 10.1002/acn3.160

By:

Hu, William T.;
Watts, Kelly D.;
Shaw, Leslie M.;
Howell, Jennifer C.;
Trojanowski, John Q.;
Basra, Sundeep;
Glass, Jonathan D.;
Lah, James J.;
Levey, Allan I.

Publication type:

Article

Effect of Apolipoprotein E ɛ4 Carrier Status on Cognitive Response to Acetylcholinesterase Inhibitors in Patients with Alzheimer’s Disease: A Systematic Review and Meta-Analysis.

Published in:

Dementia & Geriatric Cognitive Disorders, 2018, v. 45, n. 5/6, p. 335, doi. 10.1159/000490175

By:

Cheng, Ying-Chih;
Huang, Yu-Chen;
Liu, Hsing-Cheng

Publication type:

Article

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer’s Disease Sequencing Project.

Published in:

Dementia & Geriatric Cognitive Disorders, 2018, v. 45, n. 1/2, p. 1, doi. 10.1159/000485503

By:

Blue, Elizabeth E.;
Bis, Joshua C.;
Dorschner, Michael O.;
Tsuang, Debby W.;
Barral, Sandra M.;
Beecham, Gary;
Below, Jennifer E.;
Bush, William S.;
Butkiewicz, Mariusz;
Cruchaga, Carlos;
DeStefano, Anita;
Farrer, Lindsay A.;
Goate, Alison;
Haines, Jonathan;
Jaworski, Jim;
Jun, Gyungah;
Kunkle, Brian;
Kuzma, Amanda;
Lee, Jenny J.;
Lunetta, Kathryn L.

Publication type:

Article

Associations between DNA Damage, DNA Base Excision Repair Gene Variability and Alzheimer's Disease Risk.

Published in:

Dementia & Geriatric Cognitive Disorders, 2016, v. 41, n. 3/4, p. 152, doi. 10.1159/000443953

By:

Kwiatkowski, Dominik;
Czarny, Piotr;
Toma, Monika;
Jurkowska, Natalia;
Sliwinska, agnieszka;
Drzewoski, Jozef;
Bachurska, agnieszka;
Szemraj, Janusz;
Maes, Michael;
Berk, Michael;
Su, Kuan-Pin;
Galecki, Piotr;
Sliwinski, Tomasz

Publication type:

Article

Association Study and Meta-Analysis of Polymorphisms, Methylation Profiles, and Peripheral mRNA Expression of the Serotonin Transporter Gene in Patients with Alzheimer's Disease.

Published in:

Dementia & Geriatric Cognitive Disorders, 2016, v. 41, n. 5/6, p. 334, doi. 10.1159/000447324

By:

Yamazaki, Kiyohiro;
Yoshino, Yuta;
Mori, Takaaki;
Okita, Mitsuo;
Yoshida, Taku;
Mori, Yoko;
Ozaki, Yuki;
Sao, Tomoko;
Iga, Jun-ichi;
Ueno, Shu-ichi

Publication type:

Article

Altered APP Carboxyl-Terminal Processing Under Ferrous Iron Treatment in PC12 Cells.

Published in:

Korean Journal of Physiology & Pharmacology, 2013, v. 17, n. 3, p. 189, doi. 10.4196/kjpp.2013.17.3.189

By:

Chi Hyun Kim;
Yeong-Min Yoo

Publication type:

Article

Integrating brain imaging endophenotypes with GWAS for Alzheimer's disease.

Published in:

Quantitative Biology, 2021, v. 9, n. 2, p. 185, doi. 10.1007/s40484-020-0202-9

By:

Knutson, Katherine A.;
Wei Pan

Publication type:

Article

Vascular dysfunction-associated with Alzheimer's disease.

Published in:

Clinical Hemorheology & Microcirculation, 2016, v. 64, n. 4, p. 679, doi. 10.3233/CH-168047

By:

Carelli-Alinovi, Cristiana;
Dinarelli, Simone;
Girasole, Marco;
Misiti, Francesco

Publication type:

Article

Protecting Research Subject Welfare in Preventive Trials for Autosomal Dominant Alzheimer's Disease.

Published in:

American Journal of Bioethics, 2015, v. 15, n. 4, p. 83, doi. 10.1080/15265161.2015.1011009

By:

Taylor, Holly A.;
Kuwana, Ellen;
Wilfond, Benjamin S.

Publication type:

Article

Barriers and Facilitators to the Consent Process in a Study of Complex Genetic Factors.

Published in:

American Journal of Bioethics, 2015, v. 15, n. 4, p. 89, doi. 10.1080/15265161.2015.1011013

By:

Simpson, Anne R.

Publication type:

Article

Early-onset Alzheimer's disease caused by PSEN1 gene mutation: two cases reports and literature review.

Published in:

Chinese Journal of Contemporary Neurology & Neurosurgery, 2021, v. 21, n. 11, p. 967, doi. 10.3969/j.issn.1672-6731.2021.11.008

By:

ZHANG Yuan;
SUN Meng-fan;
JIA Zi-yan;
JIANG Ji-wei;
WANG Yan-li;
XU Jun

Publication type:

Article

Studies on the association between Alzheimer's disease and vascular risk factors: reports from China.

Published in:

Chinese Journal of Contemporary Neurology & Neurosurgery, 2015, v. 15, n. 7, p. 518, doi. 10.3969/j.issn.1672-6731.2015.07.004

By:

LI Ya;
LONG Hui;
CHU Lan;
LIU Fang;
TIAN Tian;
HE Dian

Publication type:

Article

Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age.

Published in:

Chemical Senses, 2016, v. 41, n. 5, p. 433, doi. 10.1093/chemse/bjw018

By:

Roddick, Kyle M.;
Roberts, Amelia D.;
Schellinck, Heather M.;
Brown, Richard E.

Publication type:

Article

Early-onset axonal pathology in a novel P301 S- Tau transgenic mouse model of frontotemporal lobar degeneration.

Published in:

Neuropathology & Applied Neurobiology, 2015, v. 41, n. 7, p. 906, doi. 10.1111/nan.12233

By:

Eersel, Janet;
Stevens, Claire H.;
Przybyla, Magdalena;
Gladbach, Amadeus;
Stefanoska, Kristie;
Chan, Chesed Kai‐Xin;
Ong, Wei‐Yi;
Hodges, John R.;
Sutherland, Greg T.;
Kril, Jillian J.;
Abramowski, Dorothee;
Staufenbiel, Matthias;
Halliday, Glenda M.;
Ittner, Lars M.

Publication type:

Article

Review: An update on clinical, genetic and pathological aspects of frontotemporal lobar degenerations.

Published in:

Neuropathology & Applied Neurobiology, 2015, v. 41, n. 7, p. 858, doi. 10.1111/nan.12250

By:

Lashley, Tammaryn;
Rohrer, Jonathan D.;
Mead, Simon;
Revesz, Tamas

Publication type:

Article

In This Issue.

Published in:: Neuropathology & Applied Neurobiology, 2014, v. 40, n. 2, p. 93, doi. 10.1111/nan.12113
Publication type:: Article

Microglial alterations in human Alzheimer's disease following Aβ42 immunization.

Published in:

Neuropathology & Applied Neurobiology, 2011, v. 37, n. 5, p. 513, doi. 10.1111/j.1365-2990.2010.01156.x

By:

Zotova, E.;
Holmes, C.;
Johnston, D.;
Neal, J. W.;
Nicoll, J. A. R.;
Boche, D.

Publication type:

Article

GENETIC AND NON-GENETIC FACTORS RESPONSIBLE FOR MITOCHONDRIAL FAILURE AND ALZHEIMER'S DISEASE.

Published in:

Genetika (0534-0012), 2014, v. 46, n. 2, p. 631, doi. 10.2298/GENSR1402631G

By:

Kuo GAO;
Meiying NIU;
Xing ZHAI;
Youliang HUANG;
Xin TIAN;
Tiangang LI

Publication type:

Article

APOE Gene polymorphism among Jordanian Alzheimer's patients with relation to lipid profile.

Published in:

Neurosciences, 2018, v. 23, n. 1, p. 29, doi. 10.17712/nsj.2018.1.20170169

By:

Shafagoj, Yanal A.;
Naffa, Randa G.;
El-Khateeb, Mohammed S.;
Abdulla, Yazeed L.;
Al-Qaddoumi, Aseem A.;
Khatib, Faisal A.;
Al-Motassem, Yousef F.;
Al-Khateeb, Eman M.

Publication type:

Article

Education and Genetic Risk Modulate Hippocampal Structure in Alzheimer's Disease.

Published in:

Aging & Disease, 2016, v. 7, n. 5, p. 553, doi. 10.14336/AD.2016.0305

By:

Baumgaertel, Johanna;
Haussmann, Robert;
Gruschwitz, Antonia;
Werner, Annett;
Osterrath, Antje;
Lange, Jan;
Donix, Katharina L.;
Linn, Jennifer;
Donix, Markus

Publication type:

Article

Analysis of Topological Parameters of Complex Disease Genes Reveals the Importance of Location in a Biomolecular Network.

Published in:

Genes, 2019, v. 10, n. 2, p. 143, doi. 10.3390/genes10020143

By:

Zhao, Xiaohui;
Liu, Zhi-Ping

Publication type:

Article

Improving the Gene Ontology Resource to Facilitate More Informative Analysis and Interpretation of Alzheimer's Disease Data.

Published in:

Genes, 2018, v. 9, n. 12, p. 593, doi. 10.3390/genes9120593

By:

Kramarz, Barbara;
Roncaglia, Paola;
Meldal, Birgit H. M.;
Huntley, Rachael P.;
Martin, Maria J.;
Orchard, Sandra;
Parkinson, Helen;
Brough, David;
Bandopadhyay, Rina;
Hooper, Nigel M.;
Lovering, Ruth C.

Publication type:

Article

Associations of Coffee and Tea Consumption on Neural Network Connectivity: Unveiling the Role of Genetic Factors in Alzheimer's Disease Risk.

Published in:

Nutrients, 2024, v. 16, n. 24, p. 4303, doi. 10.3390/nu16244303

By:

Li, Tianqi;
Fili, Mohammad;
Mohammadiarvejeh, Parvin;
Dawson, Alice;
Hu, Guiping;
Willette, Auriel A.

Publication type:

Article

Alzheimer's Disease Genetic Influences Impact the Associations between Diet and Resting-State Functional Connectivity: A Study from the UK Biobank.

Published in:

Nutrients, 2023, v. 15, n. 15, p. 3390, doi. 10.3390/nu15153390

By:

Li, Tianqi;
Willette, Auriel A.;
Wang, Qian;
Pollpeter, Amy;
Larsen, Brittany A.;
Mohammadiarvejeh, Parvin;
Fili, Mohammad

Publication type:

Article

Germline mutational analysis of presenilin 1 and APP genes in Jewish-Israeli individuals with familial or early-onset Alzheimer disease using denaturing gradient gel electrophoresis (DGGE).

Published in:

European Journal of Human Genetics, 1998, v. 6, n. 2, p. 176, doi. 10.1038/sj.ejhg.5200160

By:

Reznik-Wolf, Haike;
Treves, Therese A;
Shabtai, Herzel;
Aharon-Peretz, Judith;
Chapman, Joab;
Davidson, Michael;
Barkai, Gad;
St George Hyslop, Peter H;
Goldman, Boleslaw;
Korczyn, Amos D;
Friedman, Eitan

Publication type:

Article

Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons.

Published in:

Molecular Brain, 2015, v. 8, p. 1, doi. 10.1186/s13041-015-0163-5

By:

Naomi Mamada;
Daisuke Tanokashira;
Ai Hosaka;
Fuyuki Kametani;
Akira Tamaoka;
Wataru Araki

Publication type:

Article

Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease.

Published in:

Molecular Brain, 2015, v. 8, n. 1, p. 131, doi. 10.1186/s13041-015-0096-z

By:

Tiwari, Sachin S.;
d'Orange, Marie;
Troakes, Claire;
Shurovi, Badrun N.;
Engmann, Olivia;
Noble, Wendy;
Hortobágyi, Tibor;
Giese, Karl P.

Publication type:

Article

Transcriptional regulation and its misregulation in Alzheimer's disease.

Published in:

Molecular Brain, 2013, v. 6, n. 1, p. 1

By:

Xiao-Fen Chen;
Yun-wu Zhang;
Huaxi Xu;
Guojun Bu

Publication type:

Article

Identifying genetic interactions associated with late-onset Alzheimer's disease.

Published in:

BioData Mining, 2014, v. 7, n. 1, p. 39, doi. 10.1186/s13040-014-0035-z

By:

Floudas, Charalampos S.;
Um, Nara;
Kamboh, M. Ilyas;
Barmada, Michael M.;
Visweswaran, Shyam

Publication type:

Article

Genetic Variants of Synaptic Vesicle and Presynaptic Plasma Membrane Proteins In Alzheimer's Disease.

Published in:

Archives of Neuropsychiatry / Nöropsikiyatri Arşivi, 2012, v. 49, n. 4, p. 294, doi. 10.4274/npa.y6244

By:

EDGÜNLÜ, Tuba Gökdoğan;
ÖZGE, Aynur;
YALIN, Osman Özgür;
KUL, Seval;
ERDAL, Mehmet Emin

Publication type:

Article

Random forest prediction of Alzheimer’s disease using pairwise selection from time series data.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211558

By:

Moore, P. J.;
Lyons, T. J.;
Gallacher, J.;
null, null

Publication type:

Article

Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer’s disease and normalized by treatment with anti-diabetic agents.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0206547

By:

Katsel, P.;
Roussos, P.;
Beeri, M. S.;
Gama-Sosa, M. A.;
Gandy, S.;
Khan, S.;
Haroutunian, V.

Publication type:

Article

Genetic association of TNF-α-308 G/A and -863 C/A polymorphisms with late onset Alzheimer's disease in Azeri Turk population of Iran.

Published in:

Journal of Research in Medical Sciences, 2011, v. 16, n. 8, p. 1006

By:

Mohaddes Ardebili, Seijed Mojtaba;
Yeghaneh, Tarlan;
Gharesouran, Jalal;
Rezazadeh, Maryam;
Farhoudi, Mehdi;
Ayromlou, Hormoz;
Talebi, Mahnaz;
Ghojazadeh, Morteza

Publication type:

Article