Works matching DE "CLINICAL trials"
Results: 5000
Comparison of safety and efficacy of ultrasound-guided supraclavicular and infraclavicular subclavian vein cannulation in intensive care unit patients: A randomized clinical study.
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- International Journal of Critical Illness & Injury Science, 2025, v. 15, n. 1, p. 21, doi. 10.4103/ijciis.ijciis_80_24
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Impact of an interactive communication application on the satisfaction and anxiety of intubated patients admitted to intensive care units: A randomized clinical trial.
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- International Journal of Critical Illness & Injury Science, 2025, v. 15, n. 1, p. 4, doi. 10.4103/ijciis.ijciis_50_24
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Bionic concepts for assessment of defecatory function and dysfunction.
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- Techniques in Coloproctology, 2025, v. 29, n. 1, p. 1, doi. 10.1007/s10151-025-03125-3
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- Article
SGLT2 inhibitors increase low serum magnesium levels in patients with chronic kidney disease immediately after treatment.
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- Clinical & Experimental Nephrology, 2025, v. 29, n. 4, p. 452, doi. 10.1007/s10157-024-02590-8
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- Article
BTK‐Inhibition Enhances TLR‐7‐Mediated Interferon‐Alpha Production in pDCs by Blocking the Inhibitory BDCA‐2 Pathway.
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- European Journal of Immunology, 2025, v. 55, n. 2, p. 1, doi. 10.1002/eji.202450985
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NK Cell Immaturity and NKp30 Expression Positively Correlate with Clinical Outcome in Multiple Myeloma Patients from the IFM2009 Clinical Trial.
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- European Journal of Immunology, 2025, v. 55, n. 2, p. 1, doi. 10.1002/eji.202451191
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Effects of Different Bowel Preparation Regimens and Age Factors on the Gut Microbiota: A Prospective Randomized Controlled Study.
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- Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 3, p. 599, doi. 10.1111/jgh.16868
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Probiotics Combined With Trimebutine for the Treatment of Irritable Bowel Syndrome Patients: A Systematic Review and Meta‐Analysis.
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- Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 3, p. 677, doi. 10.1111/jgh.16858
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Tranexamic Acid With Acid Suppression Versus Acid Suppression Alone as Therapy for Upper Gastrointestinal Bleeding: A Meta‐Analysis of Randomized Controlled Trials.
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- Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 2, p. 398, doi. 10.1111/jgh.16842
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Pharmacokinetics and Safety Profile of SNS812, a First in Human Fully Modified siRNA Targeting Wide‐Spectrum SARS‐CoV‐2, in Healthy Subjects.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70202
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First‐In‐Human Safety, Tolerability, and Pharmacokinetics of PPI‐1011, a Synthetic Plasmalogen Precursor.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70195
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Agents for Change: Artificial Intelligent Workflows for Quantitative Clinical Pharmacology and Translational Sciences.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70188
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Japanese Phase 1 Study for Global Development of Anti‐TL1A Antibody PF‐06480605: A Randomized, Placebo‐Controlled, Single‐Ascending Dose Study.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70187
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Exploration of Using an Open‐Source Large Language Model for Analyzing Trial Information: A Case Study of Clinical Trials With Decentralized Elements.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70183
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Pharmacokinetics and Pharmacodynamics of KT‐474, a Novel Selective Interleukin‐1 Receptor–Associated Kinase 4 (IRAK4) Degrader, in Healthy Adults.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70181
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Safety, Tolerability, and Pharmacokinetics of SC1011 (Sufenidone), a Novel Antifibrotic Small Molecule, in Phase 1 Studies in Healthy Subjects.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70179
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Evaluation of the Landscape of Pharmacodynamic Biomarkers in GM1 and GM2 Gangliosidosis.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70176
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Population Pharmacokinetic and Exposure–Response Analyses for Ponatinib in the Phase 3 PhALLCON Study.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70175
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A Tutorial and Use Case Example of the eXtreme Gradient Boosting (XGBoost) Artificial Intelligence Algorithm for Drug Development Applications.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70172
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Assessment of Food Effect and pH‐Dependent Drug–Drug Interactions of Fruquintinib in Healthy Subjects.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70168
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- Article
Effect of E7777 Immunogenicity on Pharmacokinetics, Efficacy, and Safety in Adult Patients With Relapsed or Refractory Cutaneous T‐Cell Lymphoma.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70166
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Surfing the T Wave: A Primer on ECG T Wave Morphologies Encountered in Clinical Trials and Impact on the QT Interval and Patient Safety.
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- CTS: Clinical & Translational Science, 2025, v. 18, n. 3, p. 1, doi. 10.1111/cts.70145
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Cystectomy and lymphadenectomy – we now node how far to go!
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- BJU International, 2025, v. 135, n. 3, p. 425, doi. 10.1111/bju.16599
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Adjuvant immunotherapy for high‐risk renal cell carcinoma—now or never?
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- BJU International, 2025, v. 135, n. 2, p. 235, doi. 10.1111/bju.16584
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Real‐world outcomes for high‐risk non‐muscle‐invasive bladder cancer: screened patients for the BRAVO trial.
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- BJU International, 2025, v. 135, n. 2, p. 329, doi. 10.1111/bju.16516
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- Article
Substantia nigra degeneration in spinocerebellar ataxia 2 and 7 using neuromelanin‐sensitive imaging.
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- European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.70035
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- Article
The efficacy of remote ischemic conditioning for outcomes in ischemic stroke patients with or without prior stroke: A post hoc analysis of the RICAMIS trial.
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- European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.70032
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How well is the female population represented in clinical trials with infusion therapies for Parkinson's disease? A systematic review and metanalysis.
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- European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.70024
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Enhancing multisensory rehabilitation of visual field defects with transcranial direct current stimulation: A randomized clinical trial.
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- European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.16559
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Deep brain stimulation for severe dystonia associated with Wilson disease: A prospective multicenter meta‐analysis of an N‐of‐1 trial.
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- European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.16524
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Phenotype–genotype correlation in X‐linked Charcot‐Marie‐Tooth disease: A French cohort study.
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- European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.16523
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Opicapone as adjunct to levodopa in treated Parkinson's disease without motor complications: A randomized clinical trial.
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- European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.16420
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Combination of Methyl Aminolevulinate‐Based Photodynamic Therapy and Antibiotics in the Treatment of Mycobacterium gordonae Scalp Infection: A Case Report.
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- Photodermatology, Photoimmunology & Photomedicine, 2025, v. 41, n. 2, p. 1, doi. 10.1111/phpp.70012
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Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder.
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- Basic & Clinical Pharmacology & Toxicology, 2025, v. 136, n. 3, p. 1, doi. 10.1111/bcpt.70004
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A software‐based observational coding approach for evaluating paediatric dental pain, anxiety, and fear.
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- International Journal of Paediatric Dentistry, 2025, v. 35, n. 2, p. 241, doi. 10.1111/ipd.13227
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- Article
Patidegib: a novel, promising treatment for basal cell carcinoma lesions in patients with Gorlin syndrome.
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- British Journal of Dermatology, 2025, v. 192, n. 4, p. 565, doi. 10.1093/bjd/ljae515
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Guselkumab for the treatment of moderate-to-severe plaque psoriasis in paediatric patients: results of the phase III randomized placebo-controlled PROTOSTAR study.
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- British Journal of Dermatology, 2025, v. 192, n. 4, p. 618, doi. 10.1093/bjd/ljae502
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Integrating artificial intelligence into skin cancer pathways: the opportunities and obstacles.
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- British Journal of Dermatology, 2025, v. 192, n. 4, p. 738, doi. 10.1093/bjd/ljae480
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Long-term efficacy and safety of secukinumab in patients with moderate-to-severe hidradenitis suppurativa: week 104 results from the SUNSHINE and SUNRISE extension trial.
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- British Journal of Dermatology, 2025, v. 192, n. 4, p. 629, doi. 10.1093/bjd/ljae469
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Topical application of the Hedgehog inhibitor patidegib in patients with Gorlin syndrome: a phase II trial.
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- British Journal of Dermatology, 2025, v. 192, n. 4, p. 611, doi. 10.1093/bjd/ljae444
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Long-term management of moderate-to-severe atopic dermatitis with lebrikizumab and concomitant topical corticosteroids: a 68-week randomized double-blind placebo-controlled phase III trial in Japan (ADhere-J).
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- British Journal of Dermatology, 2025, v. 192, n. 4, p. 597, doi. 10.1093/bjd/ljae394
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A phase 1/2 safety and efficacy study of TAK‐754 gene therapy: The challenge of achieving durable factor VIII expression in haemophilia A clinical trials.
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- Haemophilia, 2025, v. 31, n. 1, p. 108, doi. 10.1111/hae.15121
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Bleed treatment with eptacog beta (rFVIIa) results in a low incidence of rebleeding in adult and adolescent patients with haemophilia A or B with inhibitors.
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- Haemophilia, 2025, v. 31, n. 1, p. 78, doi. 10.1111/hae.15109
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Fully guided system for position‐predictable autotransplantation of teeth: A randomized clinical trial.
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- International Endodontic Journal, 2025, v. 58, n. 4, p. 550, doi. 10.1111/iej.14193
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Pulp sensibility responses following complete and partial pulpotomy in mature permanent molars with carious pulpal exposure and symptomatic irreversible pulpitis: Analysis of pooled data from three randomized clinical trials.
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- International Endodontic Journal, 2025, v. 58, n. 3, p. 420, doi. 10.1111/iej.14188
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Response to letter to editor: Clinical outcome of guided endodontics versus freehand drilling: A controlled clinical trial, single arm with external control group.
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- International Endodontic Journal, 2025, v. 58, n. 3, p. 543, doi. 10.1111/iej.14177
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A 4‐year follow‐up of root canal obturation using a calcium silicate‐based sealer and a zinc oxide‐eugenol sealer: A randomized clinical trial.
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- International Endodontic Journal, 2025, v. 58, n. 2, p. 193, doi. 10.1111/iej.14167
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Clinical outcome of guided endodontics versus freehand drilling: A controlled clinical trial, single arm with external control group.
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- International Endodontic Journal, 2025, v. 58, n. 2, p. 209, doi. 10.1111/iej.14157
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Participation and relative cost of attendance by direct‐mail compared to opt‐in invitation strategy for HPV self‐sampling targeting cervical screening non‐attenders: A large‐scale, randomized, pragmatic study.
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- International Journal of Cancer, 2025, v. 156, n. 8, p. 1594, doi. 10.1002/ijc.35263
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Clinical outcomes by baseline metastases in patients with renal cell carcinoma treated with lenvatinib plus pembrolizumab versus sunitinib: Post hoc analysis of the CLEAR trial.
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- International Journal of Cancer, 2025, v. 156, n. 7, p. 1326, doi. 10.1002/ijc.35288
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- Article