Oral Communications.

This document provides summaries of several articles related to pharmacology and toxicology. The first article focuses on late adverse events in patients with aggressive B-cell non-Hodgkin lymphoma treated with CAR T-cell therapy, finding that infections and cytopenias were the most common late adverse events. The second article discusses the implementation of automated systems for detecting adverse drug reactions in hospitalized patients, which improved patient safety. The third article examines the profile of patients admitted to a hospital for acute drug poisoning, with benzodiazepines, 4-aminophenol derivatives, and antipsychotics being the most common substances involved. The fourth article characterizes a patient cohort with multiple adverse drug reactions, finding that comorbidities, age, and sex played a role in adverse drug reaction generation. The final article emphasizes the importance of data quality in multi-database pharmacoepidemiologic studies for generating reliable real-world evidence. Additionally, there are summaries of studies on the effectiveness and cost of monoclonal antibodies for migraine treatment, non-response to antiplatelet therapy in high-risk patients, the scientific production generated by a database of real-world data, therapeutic recommendations for ADHD patients, and the chemopreventive effect of antiplatelet drugs on digestive cancers.

DRUG side effects; MEDICAL sciences; SCIENTIFIC knowledge; CHILD patients; CALCITONIN gene-related peptide; SUMATRIPTAN; EPIGENOMICS; PHARMACOGENOMICS

Basic & Clinical Pharmacology & Toxicology, 2024, Vol 135, p15

1742-7835

Academic Journal

10.1111/bcpt.14063