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- Title
Interaction of OTC drug noscapine and acenocoumarol and phenprocoumon.
- Authors
Lokhorst, Bianca; Rolfes, Leàn; Jessurun, Naomi T.
- Abstract
The article presents a study exploring the interaction of over-the-counter (OTC) drug noscapine and acenocoumarol and phenprocoumon. Topics discussed include information on the anticoagulant effects of the drugs by inhibiting the synthesis of vitamin K–dependent clotting factors; determining the nature of the drug interaction between noscapine and warfarin; and the information on the interaction between vitamin K antagonists and noscapine resulting in increased international normalized ratio.
- Subjects
NONPRESCRIPTION drugs; NOSCAPINE; DRUG interactions; BLOOD coagulation factors; WARFARIN; INTERNATIONAL normalized ratio
- Publication
British Journal of Clinical Pharmacology, 2019, Vol 85, Issue 5, p1041
- ISSN
0306-5251
- Publication type
Academic Journal
- DOI
10.1111/bcp.13887