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- Title
Furosemide attenuates tubulointerstitial injury and allows functional testing of porcine kidneys during normothermic machine perfusion.
- Authors
Ogurlu, Baran; Hamelink, Tim L; Lantinga, Veerle A; Leuvenink, Henri G D; Pool, Merel B F; Moers, Cyril
- Abstract
Normothermic machine perfusion (NMP) is a promising pretransplant kidney quality assessment platform, but it remains crucial to increase its diagnostic potential while ensuring minimal additional injury to the already damaged kidney. Interventions that alter tubular transport can influence renal function and injury during perfusion. This study aimed to determine whether furosemide and desmopressin affect renal function and injury during NMP.
- Publication
Artificial organs, 2024, Vol 48, Issue 6, p595
- ISSN
1525-1594
- Publication type
Journal Article
- DOI
10.1111/aor.14705