Works matching DE "CYTOSINE deaminase"

Results: 71

Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 6, p. 485, doi. 10.1038/nsmb.3033

By:

Kouno, Takahide;
Luengas, Elizabeth M;
Shigematsu, Megumi;
Shandilya, Shivender M D;
Zhang, JingYing;
Chen, Luan;
Hara, Mayuko;
Schiffer, Celia A;
Harris, Reuben S;
Matsuo, Hiroshi

Publication type:

Article

Accumulation of AID in immunoglobulin variable genes in the absence of Topoisomerase I.

Published in:

Turkish Journal of Immunology, 2016, v. 4, p. 22

By:

Saribasak, Huseyin;
Maul, Robert W.;
Cao, Zheng;
Gearhart, Patricia J.

Publication type:

Article

New treatments based on gene therapy approaches to increase radiosensitisation in prostate cancer.

Published in:

Prostate Cancer & Prostatic Diseases, 2000, v. 3, n. 1, p. S15, doi. 10.1038/sj.pcan.4500439

By:

García-Sánchez, F;
Lledó, E;
Alvarez, A;
Lillo, R;
Llorente, C

Publication type:

Article

Therapeutic effects of adenovirus‑mediated CD and NIS expression combined with Na<sup>131</sup>I/5‑FC on human thyroid cancer.

Published in:

Oncology Letters, 2017, v. 14, n. 6, p. 7431, doi. 10.3892/ol.2017.7175

By:

Meng‑hui Yuan;
Long‑xiao Wei;
Run‑suo Zhou;
Hai‑feng Xu;
Jun‑yan Wang;
Qian‑rong Bai

Publication type:

Article

A double suicide gene system driven by vascular endothelial growth factor promoter selectively kills human hepatocellular carcinoma cells.

Published in:

Oncology Letters, 2016, v. 11, n. 5, p. 3152, doi. 10.3892/ol.2016.4360

By:

KAI WU;
LIUCHENG YANG;
ZONGHAI HUANG;
HAIJUN ZHAO;
JIANJUN WANG;
SHUAI XU

Publication type:

Article

VP22 and cytosine deaminase fusion gene modified tissue-engineered neural stem cells for glioma therapy.

Published in:

Journal of Cancer Research & Clinical Oncology, 2013, v. 139, n. 3, p. 475, doi. 10.1007/s00432-012-1347-3

By:

Jin, Guishan;
Zhou, Yiqiang;
Chai, Qi;
Zhu, Guidong;
Xu, Fujian;
Liu, Fusheng

Publication type:

Article

The antitumor effect of mesenchymal stem cells transduced with a lentiviral vector expressing cytosine deaminase in a rat glioma model.

Published in:

Journal of Cancer Research & Clinical Oncology, 2012, v. 138, n. 2, p. 347, doi. 10.1007/s00432-011-1104-z

By:

Fei, Song;
Qi, Xing;
Kedong, Song;
Guangchun, Ji;
Jian, Liu;
Wei, Qin

Publication type:

Article

Baculoviral vector loaded mesenchymal stem cells as efficient gene therapy tools for cancer treatment.

Published in:

Turkish Journal of Biology, 2016, v. 40, n. 5, p. 1121, doi. 10.3906/biy-1601-76

By:

AKTAŞ, Sedef Hande;
AKBULUT, Hakan;
ELÇİN, Ayşe Eser;
PARMAKSIZ, Mahmut;
KESKİN, Arzu Aktan;
ÇÖLERİ CİHAN, Arzu;
ELÇİN, Yaşar Murat;
İÇLİ, Fikri

Publication type:

Article

Processive DNA Demethylation via DNA Deaminase-Induced Lesion Resolution.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0097754

By:

Franchini, Don-Marc;
Chan, Chun-Fung;
Morgan, Hugh;
Incorvaia, Elisabetta;
Rangam, Gopinath;
Dean, Wendy;
Santos, Fatima;
Reik, Wolf;
Petersen-Mahrt, Svend K.

Publication type:

Article

Interaction of APOBEC3A with DNA Assessed by Atomic Force Microscopy.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099354

By:

Shlyakhtenko, Luda S.;
Lushnikov, Alexander J.;
Li, Ming;
Harris, Reuben S.;
Lyubchenko, Yuri L.

Publication type:

Article

Retroviral Restriction Factor APOBEC3G Delays the Initiation of DNA Synthesis by HIV-1 Reverse Transcriptase

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064196

By:

Adolph, Madison B.;
Webb, Jonathon;
Chelico, Linda

Publication type:

Article

In Vitro and In Vivo Effect of 5-FC Combined Gene Therapy with TNF-α and CD Suicide Gene on Human Laryngeal Carcinoma Cell Line Hep-2.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061136

By:

Chai, Li-Ping;
Wang, Zhang-Feng;
Liang, Wei-Ying;
Chen, Lei;
Chen, Dan;
Wang, An-Xun;
Zhang, Zhao-Qiang

Publication type:

Article

Genome-Wide Detection of Genes Targeted by Non-Ig Somatic Hypermutation in Lymphoma.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040332

By:

Yanwen Jiang;
David Soong, T.;
Ling Wang;
Melnick, Ari M.;
Elemento, Olivier

Publication type:

Article

Replication Protein A (RPA) Hampers the Processive Action of APOBEC3G Cytosine Deaminase on Single-Stranded DNA.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024848

By:

Lada, Artem G.;
Waisertreiger, Irina S.-R.;
Grabow, Corinn E.;
Prakash, Aishwarya;
Borgstahl, Gloria E. O.;
Rogozin, Igor B.;
Pavlov, Youri I.

Publication type:

Article

Effects of prostaglandin E<sub>2</sub> on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansion.

Published in:

FASEB Journal, 2014, v. 28, n. 2, p. 627, doi. 10.1096/fj.13-237792

By:

Haque, Shabirul;
Xiao Jie Yan;
Rosen, Lisa;
McCormick, Steven;
Chiorazzi, Nicholas;
Mongini, Patricia K. A.

Publication type:

Article

A bacterial gene codA encoding cytosine deaminase is an effective conditional negative selectable marker in Glycine max.

Published in:

Plant Cell Reports, 2015, v. 34, n. 10, p. 1707, doi. 10.1007/s00299-015-1818-5

By:

Shao, Min;
Michno, Jean-Michel;
Hotton, Sara;
Blechl, Ann;
Thomson, James

Publication type:

Article

A Mutated Cytosine Deaminase Gene, codA (D314A), as an Efficient Negative Selection Marker for Gene Targeting in Rice.

Published in:

Plant & Cell Physiology, 2014, v. 55, n. 3, p. 658, doi. 10.1093/pcp/pct183

By:

Osakabe, Keishi;
Nishizawa-Yokoi, Ayako;
Ohtsuki, Namie;
Osakabe, Yuriko;
Toki, Seiichi

Publication type:

Article

Antiproliferative effect of double suicide gene delivery mediated by polyamidoamine dendrimers in human Tenon's capsule fibroblasts.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 6, p. 5473, doi. 10.3892/etm.2017.5235

By:

JIN YANG;
LIU KUN SHI;
HUI MIN SUN;
YAN MING WANG

Publication type:

Article

Effect of alginate microencapsulation on the catalytic efficiency and in vitro enzyme-prodrug therapeutic efficacy of cytosine deaminase and of recombinant E. coli expressing cytosine deaminase.

Published in:

Journal of Microencapsulation, 2016, v. 33, n. 1, p. 64, doi. 10.3109/02652048.2015.1115902

By:

Funaro, Michael G.;
Nemani, Krishnamurthy V.;
Chen, Zhihang;
Bhujwalla, Zaver M.;
Griswold, Karl E.;
Gimi, Barjor

Publication type:

Article

Migration to gliomas of bone mesenchymal stem cells transfected with cytosine deaminase gene following transplantation in vivo.

Published in:

Neural Regeneration Research, 2011, v. 6, n. 19, p. 1462, doi. 10.3969/j.issn.1673-5374.2011.19.004

By:

Guangchun Ji;
Fei Song;
Qi Xing;
Jian Liu;
Kedong Song;
Daqing Zhang;
Zihan Wang

Publication type:

Article

Inhibitory effects of cytosine deaminase gene-transfected bone marrow mesenchymal stem cells on glioma cell proliferation.

Published in:

Neural Regeneration Research, 2011, v. 6, n. 16, p. 1238, doi. 10.3969/j.issn.1673-5374.2011.16.007

By:

Fei Song;
Qi Xing;
Kedong Song;
Jian Liu;
Guangchun Ji;
Yufang Ma;
Tianqing Liu;
Minghai Wei;
Xuehu Ma

Publication type:

Article

AID/APOBEC cytosine deaminase induces genome-wide kataegis.

Published in:

Biology Direct, 2012, v. 7, n. 1, p. 47, doi. 10.1186/1745-6150-7-47

By:

Lada, Artem G.;
Dhar, Alok;
Boissy, Robert J.;
Hirano, Masayuki;
Rubel, Aleksandr A.;
Rogozin, Igor B.;
Pavlov, Youri I.

Publication type:

Article

Beyond CRISPR: single base editors for human health and crop improvement.

Published in:

Current Science (00113891), 2019, v. 116, n. 3, p. 386, doi. 10.18520/cs/v116/i3/386-397

By:

Gupta, P. K.

Publication type:

Article

Inhibition of Tumor Growth by Polyarginine-Fused Mutant Cytosine Deaminase.

Published in:

Applied Biochemistry & Biotechnology, 2015, v. 175, n. 3, p. 1633, doi. 10.1007/s12010-014-1389-x

By:

Wang, Wenfei;
Zhang, Nan;
Zhao, Tingting;
Liu, Mingyao;
Zhang, Tong;
Li, Deshan

Publication type:

Article

Emerging Implications of Nonmammalian Cytosine Deaminases on Cancer Therapeutics.

Published in:

Applied Biochemistry & Biotechnology, 2012, v. 167, n. 7, p. 2103, doi. 10.1007/s12010-012-9746-0

By:

Yata, Vinod;
Gopinath, P.;
Ghosh, Siddhartha

Publication type:

Article

Elimination of the nptII marker gene in transgenic apple and pear with a chemically inducible R/Rs recombinase.

Published in:

Plant Cell, Tissue & Organ Culture, 2014, v. 117, n. 3, p. 335, doi. 10.1007/s11240-014-0443-2

By:

Righetti, L.;
Djennane, S.;
Berthelot, P.;
Cournol, R.;
Wilmot, N.;
Loridon, K.;
Vergne, E.;
Chevreau, E.

Publication type:

Article

Stabilization of Aspergillus parasiticus cytosine deaminase by immobilization on calcium alginate beads improved enzyme operational stability.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 6, p. 1217, doi. 10.3109/14756366.2012.724406

By:

Zanna, H.;
Nok, A. J.;
Ibrahim, S.;
Inuwa, H. M.

Publication type:

Article

Mesenchymal stem cells expressing cytosine deaminase inhibit growth of murine melanoma B16F10 in vivo.

Published in:

Molecular Biology, 2015, v. 49, n. 6, p. 904, doi. 10.1134/S0026893315060126

By:

Krasikova, L.;
Karshieva, S.;
Cheglakov, I.;
Belyavsky, A.

Publication type:

Article

New look at the role of progerin in skin aging.

Published in:

Menopausal Review / Przegląd Menopauzalny, 2015, v. 14, n. 1, p. 53, doi. 10.5114/pm.2015.49532

By:

Skoczyńska, Anna;
Budzisz, Elżbieta;
Dana, Agnieszka;
Rotsztejn, Helena

Publication type:

Article

Crystal structure of mimivirus uracil-DNA glycosylase.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182382

By:

Kwon, Eunju;
Pathak, Deepak;
Chang, Hyeun Wook;
Kim, Dong Young

Publication type:

Article

Increased sensitivity of glioma cells to 5-fluorocytosine following photo-chemical internalization enhanced nonviral transfection of the cytosine deaminase suicide gene.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 1, p. 29, doi. 10.1007/s11060-014-1410-9

By:

Wang, Frederick;
Zamora, Genesis;
Sun, Chung-Ho;
Trinidad, Anthony;
Chun, Changho;
Kwon, Young;
Berg, Kristian;
Madsen, Steen;
Hirschberg, Henry

Publication type:

Article

Double suicide gene therapy using human neural stem cells against glioblastoma: double safety measures.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 1, p. 49, doi. 10.1007/s11060-013-1264-6

By:

Lee, Ji;
Lee, Do-Hun;
Kim, Hyung;
Choi, Seung-Ah;
Lee, Hong;
Park, Chul-Kee;
Phi, Ji;
Wang, Kyu-Chang;
Kim, Seung;
Kim, Seung-Ki

Publication type:

Article

Improved cytotoxic effects of S almonella-producing cytosine deaminase in tumour cells.

Published in:

Microbial Biotechnology, 2015, v. 8, n. 1, p. 169, doi. 10.1111/1751-7915.12153

By:

Mesa-Pereira, Beatriz;
Medina, Carlos;
Camacho, Eva María;
Flores, Amando;
Santero, Eduardo

Publication type:

Article

Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth.

Published in:

Molecular Therapy, 2013, v. 21, n. 1, p. 101, doi. 10.1038/mt.2012.161

By:

Mizrak, Arda;
Bolukbasi, Mehmet Fatih;
Ozdener, Gokhan Baris;
Brenner, Gary J;
Madlener, Sibylle;
Erkan, Erdogan Pekcan;
Ströbel, Thomas;
Breakefield, Xandra O;
Saydam, Okay

Publication type:

Article

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression.

Published in:

Molecular Therapy, 2012, v. 20, n. 9, p. 1689, doi. 10.1038/mt.2012.83

By:

Perez, Omar D;
Logg, Christopher R;
Hiraoka, Kei;
Diago, Oscar;
Burnett, Ryan;
Inagaki, Akihito;
Jolson, Dawn;
Amundson, Karin;
Buckley, Taylor;
Lohse, Dan;
Lin, Amy;
Burrascano, Cindy;
Ibanez, Carlos;
Kasahara, Noriyuki;
Gruber, Harry E;
Jolly, Douglas J

Publication type:

Article

Effects of an adenoviral vector containing a suicide gene fusion on growth characteristics of breast cancer cells.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 6, p. 3227, doi. 10.3892/mmr.2014.2631

By:

HENG KONG;
CHUNLI LIU;
TING ZHU;
ZONGHAI HUANG;
LIUCHENG YANG;
QIANG LI

Publication type:

Article

Chemovirotherapy of Malignant Melanoma with a Targeted and Armed Oncolytic Measles Virus.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 4, p. 1034, doi. 10.1038/jid.2012.459

By:

Kaufmann, Johanna K;
Bossow, Sascha;
Grossardt, Christian;
Sawall, Stefanie;
Kupsch, Jörg;
Erbs, Philippe;
Hassel, Jessica C;
von Kalle, Christof;
Enk, Alexander H;
Nettelbeck, Dirk M;
Ungerechts, Guy

Publication type:

Article

Cytotoxic effect of co-expression of human hepatitis A virus 3C protease and bifunctional suicide protein FCU1 genes in a bicistronic vector.

Published in:

Molecular Biology Reports, 2017, v. 44, n. 4, p. 323, doi. 10.1007/s11033-017-4113-4

By:

Komissarov, Alexey;
Demidyuk, Ilya;
Safina, Dina;
Roschina, Marina;
Shubin, Andrey;
Lunina, Nataliya;
Karaseva, Maria;
Kostrov, Sergey

Publication type:

Article

Genomic instability: DNA transitions.

Published in:

Nature Reviews Cancer, 2013, v. 13, n. 4, p. 220, doi. 10.1038/nrc3490

By:

Alderton, Gemma K.

Publication type:

Article

Transgenic APOBECs.

Published in:

Nature Immunology, 2014, v. 15, n. 7, p. 601, doi. 10.1038/ni.2931

By:

Dempsey, Laurie A

Publication type:

Article

Characterization and Cytotoxic Activity of Cytosine Deaminase Enzyme Purified from Locally Isolated Escherichia coli.

Published in:

Baghdad Science Journal, 2018, v. 15, n. 3, p. 262, doi. 10.21123/bsj.2018.15.3.0262

By:

Hussein, Asmaa A.;
Al-Baer, Ali Saadi

Publication type:

Article

Genomic methylation patterns in archaeological barley show de-methylation as a time-dependent diagenetic process.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05559

By:

Smith, Oliver;
Clapham, Alan J.;
Rose, Pam;
Yuan Liu;
Jun Wang;
Allaby, Robin G.

Publication type:

Article

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma.

Published in:

Science Translational Medicine, 2016, v. 8, n. 341, p. 1, doi. 10.1126/scitranslmed.aad9784

By:

Cloughesy, Timothy F.;
Landolfi, Joseph;
Hogan, Daniel J.;
Bloomfield, Stephen;
Carter, Bob;
Chen, Clark C.;
Elder, J. Bradley;
Kalkanis, Steven N.;
Kesari, Santosh;
Lai, Albert;
Lee, Ian Y.;
Liau, Linda M.;
Mikkelsen, Tom;
Nghiemphu, Phioanh Leia;
Piccioni, David;
Walbert, Tobias;
Chu, Alice;
Das, Asha;
Diago, Oscar R.;
Gammon, Dawn

Publication type:

Article

Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer.

Published in:

Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-014-0498-3

By:

Harris, Reuben S.

Publication type:

Article

Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer.

Published in:

Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-014-0498-3

By:

Harris, Reuben S.

Publication type:

Article

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0155391

By:

Akre, Monica K.;
Starrett, Gabriel J.;
Quist, Jelmar S.;
Temiz, Nuri A.;
Carpenter, Michael A.;
Tutt, Andrew N. J.;
Grigoriadis, Anita;
Harris, Reuben S.

Publication type:

Article

Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149146

By:

Williams, Alan M.;
Maman, Yaakov;
Alinikula, Jukka;
Schatz, David G.

Publication type:

Article

Cytosine Deamination Is a Major Cause of Baseline Noise in Next-Generation Sequencing.

Published in:

Molecular Diagnosis & Therapy, 2014, v. 18, n. 5, p. 587, doi. 10.1007/s40291-014-0115-2

By:

Chen, Guoli;
Mosier, Stacy;
Gocke, Christopher;
Lin, Ming-Tseh;
Eshleman, James

Publication type:

Article

PC3 - 151 Toca 5: A Phase 2/3 Randomized, Open-Label Study of Toca 511, a Retroviral Replicating Vector, Combined with Toca FC versus Standard of Care in Patients Undergoing Planned Resection for Recurrent Glioblastoma (GBM) or Anaplastic Astrocytoma ...

Published in:

Canadian Journal of Neurological Sciences, 2016, v. 43, p. S17, doi. 10.1017/cjn.2016.379

By:

Zadeh, G.;
Bota, D.;
Cachia, D.;
Landolfi, J.;
Schiff, D.;
Vogelbaum, M.A.;
Walbert, T.;
Tran, D.;
Chu, A.;
Das, A.;
Jolly, D.J.;
Ibañez, C.E.;
Ostertag, D.;
Sully, S.;
Cloughesy, T.F.

Publication type:

Article

OS8 - 150 Encouraging Survival with Toca 511 and Toca FC Compared to External Lomustine Control.

Published in:

Canadian Journal of Neurological Sciences, 2016, v. 43, p. S4, doi. 10.1017/cjn.2016.339

By:

Huang, T.T;
Aghi, M.K;
Chen, C.C;
Elder, J.B;
Kesari, S;
Kalkanis, S;
Kaptain, G;
Landolfi, J;
Mikkelsen, T;
Portnow, J;
Robbins, J.M;
Ostertag, D;
Das, A;
Chu, A;
Vogelbaum, M.A

Publication type:

Article