Peptic ulcer bleeding in China: A multicenter endoscopic survey of 1006 patients.

Bai, Yu; Du, Yi Qi; Wang, Dong; Zou, Duo Wu; Jin, Zhen Dong; Zhan, Xian Bao; Zhao, Xiao Yan; Sha, Wei Hong; Wang, Jiang Bin; Yu, Weng Fei; Jiang, Yi; Ye, Li Ping; Zhang, Shu Tian; Zhou, Li Ya; Chen, Min Hu; Yu, Xiao Feng; Zheng, Jian Wei; Wang, Rong Quan; Huang, Xiao Jun; Chen, Dong Feng

Objective We aimed to describe the clinical picture, management and outcomes of Chinese patients with peptic ulcer bleeding (PUB), especially in those with high risks. Methods A multicenter endoscopic survey was conducted. All consecutive patients with endoscopy confirmed PUB from October 2010 to June 2011 were enrolled. Data including patients' gender, age, symptoms and endoscopic findings, Forrest classification, and endoscopic and medical treatment were documented. High-risk ulcer was defined as Forrest grades Ia to IIb upon endoscopy. Rates of rebleeding, surgery and mortality were recorded. Results In all, 1006 patients were included. Of these 437 (43.4%) were categorized with high-risk PUB, among whom 110 (25.2%) received endoscopic treatment, and the success rate was 99.1%. Rebleeding rates 1-3 days, 4-5 days and 6-30 days after treatment in high-risk patients who did and did not receive endoscopic treatment were 10.9% versus 10.4%, 3.6% versus 3.7% and 0.9% versus 1.5%, respectively. The surgery rates of high-risk patients with or without endoscopic treatment were 1.8% (2/110) versus 1.8% (6/327). During the 9-month study period, two patients with high-risk PUB died, therefore, the overall mortality rate of high-risk PUB was 0.5% (2/437). Conclusion The study suggests that the proportions of high-risk PUB in China is 43.4%, while rebleeding and surgery rate after endoscopic treatment as well as the mortality rate of high-risk PUB in China are 15.6%, 1.8% and 0.5%, respectively.

CHINA; PEPTIC ulcer diagnosis; ENDOSCOPIC surgery; HEMORRHAGE; SURGICAL excision

Journal of Digestive Diseases, 2014, Vol 15, Issue 1, p5

1751-2972

Academic Journal

10.1111/1751-2980.12104