Title: Germline and somatic genetic testing in ovarian cancer patients.
Authors: Chandrasekaran, D.; Manchanda, R.
Abstract: The article focuses on genetic testing for germline BRCA1/BRCA2 mutations in epithelial ovarian cancer (EOC) which can benefit from targeted therapy such as poly adenosine diphosphate (ADP) ribose polymerase inhibitors. It mentions risk mutation carriers access to opportunities for screening and chemoprevention selective estrogen receptor modulators for breast cancer. It also mentions importance of offering genetic testing to all women.
Subjects: GENETIC testing; GERM cells; BRCA genes; OVARIAN epithelial cancer; ADENOSINE diphosphate ribose; CHEMOPREVENTION; SELECTIVE estrogen receptor modulators; BREAST cancer; OVARIAN tumors; PROTEINS
Publication: BJOG: An International Journal of Obstetrics & Gynaecology, 2018, Vol 125, Issue 11, p1460
ISSN: 1470-0328
Publication type: Academic Journal
DOI: 10.1111/1471-0528.15225

Germline and somatic genetic testing in ovarian cancer patients.

Chandrasekaran, D.; Manchanda, R.