Parental physical and lifestyle factors and their association with newborn body composition.

McCarthy, FP; Khashan, AS; Murray, D; Kiely, M; Hourihane, J O'B; Pasupathy, D; Kenny, LC; McCarthy, F P; Khashan, A S; Kenny, L C; SCOPE Ireland Cohort study and the Cork BASELINE Birth Cohort Study

<bold>Objective: </bold>To investigate the parental physical and lifestyle determinants of newborn body composition.<bold>Design: </bold>Prospective cohort study.<bold>Setting: </bold>Cork University Maternity Hospital, a tertiary referral hospital in Cork, Ireland.<bold>Population: </bold>All babies were recruited as part of a prospective birth cohort, Babies After<bold>Scope: </bold>Evaluating the Longitudinal Impact Using Neurological and Nutritional Endpoints (BASELINE). These babies were recruited from women who had participated in the Screening of Pregnancy Endpoints (SCOPE) study Ireland, a prospective, multicentre cohort study<bold>Methods: </bold>Multivariate linear regression was used to analyse the effect of a range of maternal and paternal physical and lifestyle features on neonatal body fat percentage (BF%).<bold>Main Outcome Measures: </bold>Neonatal BF%. Neonatal adiposity was assessed within 48 hours of birth using air displacement plethysmography (PEAPOD(®) ).<bold>Results: </bold>In all, 1243 infants were enrolled in the study. Increasing maternal body mass index (adjusted mean difference 0.09; 0.04, 0.15) and waist height ratio (adjusted mean difference 6.59; 0.27, 12.92) were significantly associated with increased neonatal BF%. In contrast, maternal smoking was associated with reduced neonatal BF% compared with non smokers (adjusted mean difference -0.55; -1.07, -0.03). Infant sex significantly altered neonatal BF%, with female infants having higher neonatal BF% compared with male infants (adjusted mean difference 1.98; 1.54, 2.53). No association was observed between paternal body mass index (BMI), paternal age or paternal smoking and neonatal BF%.<bold>Conclusions: </bold>Maternal smoking, BMI, waist height ratio and infant sex were associated with altered BF%.<bold>Tweetable Abstract: </bold>Maternal smoking, BMI, waist height ratio and infant sex are associated with altered neonatal body fat percentage.

PATERNAL age effect; CHILDBIRTH; PLETHYSMOGRAPHY; BIRTH size; PREGNANT women; WOMEN'S tobacco use

BJOG: An International Journal of Obstetrics & Gynaecology, 2016, Vol 123, Issue 11, p1824

1470-0328

Academic Journal

10.1111/1471-0528.14042