Works matching DE "PYRUVATE dehydrogenase complex"
Results: 255
Intraabdominal adhesion formation is associated with differential mRNA expression of metabolic genes PDHb and SDHa.
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- Archives of Gynecology & Obstetrics, 2012, v. 286, n. 3, p. 683, doi. 10.1007/s00404-012-2364-9
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- Article
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.
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- Nature, 2013, v. 498, n. 7452, p. 109, doi. 10.1038/nature12154
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- Article
Isoacteoside alleviates hepatocellular carcinoma progression by inhibiting PDHB-mediated reprogramming of glucose metabolism.
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- Communications Biology, 2025, p. 1, doi. 10.1038/s42003-025-07622-x
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- Article
Supramolecular Protein Assemblies: Building Blocks, Organism- or Cell-Specific Varieties, and Significance.
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- Biomolecules (2218-273X), 2024, v. 14, n. 11, p. 1342, doi. 10.3390/biom14111342
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- Article
Thermodynamics in cancers: opposing interactions between PPAR gamma and the canonical WNT/beta‐catenin pathway.
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- Clinical & Translational Medicine, 2017, v. 6, n. 1, p. 1, doi. 10.1186/s40169-017-0144-7
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- Article
Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1151502
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- Article
The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis.
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- Clinical & Experimental Immunology, 2012, v. 168, n. 3, p. 279, doi. 10.1111/j.1365-2249.2012.04581.x
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- Article
The mechanism of cancer cell death by PARP inhibitors goes beyond DNA damage alone.
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- International Journal of Cancer, 2019, v. 145, n. 9, p. 2594, doi. 10.1002/ijc.32392
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- Article
Scurvy - surprisingly not yet extinct.
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- 2017
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- Case Study
Development of a loop-mediated isothermal amplification targeting a gene within the pyruvate dehydrogenase complex, the pdhA gene, for rapid detection of Mycoplasma gallisepticum.
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- Journal of Veterinary Diagnostic Investigation, 2015, v. 27, n. 3, p. 260, doi. 10.1177/1040638715584155
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- Article
BACE1 activity impairs neuronal glucose oxidation: rescue by beta-hydroxybutyrate and lipoic acid.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00382
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- Article
Comparative Analysis of Symmetry Parameters in the E2 Inner Core of the Pyruvate Dehydrogenase Complex.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 24, p. 13731, doi. 10.3390/ijms252413731
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- Article
Insufficient Acetyl-CoA Pool Restricts the Phototrophic Production of Organic Acids in Model Cyanobacteria.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 21, p. 11769, doi. 10.3390/ijms252111769
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- Publication type:
- Article
Phenylbutyrate and Dichloroacetate Enhance the Liquid-Stored Boar Sperm Quality via PDK1 and PDK3.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 17091, doi. 10.3390/ijms242317091
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- Publication type:
- Article
(+)-Lipoic Acid Reduces Lipotoxicity and Regulates Mitochondrial Homeostasis and Energy Balance in an In Vitro Model of Liver Steatosis.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14491, doi. 10.3390/ijms241914491
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- Article
Transcriptome Analysis Reveals the Effect of PdhR in Plesiomonas shigelloides.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14473, doi. 10.3390/ijms241914473
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- Article
Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12405, doi. 10.3390/ijms241512405
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- Article
Phosphonate Inhibitors of Pyruvate Dehydrogenase Perturb Homeostasis of Amino Acids and Protein Succinylation in the Brain.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13186, doi. 10.3390/ijms232113186
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- Article
Integrated or Independent Actions of Metformin in Target Tissues Underlying Its Current Use and New Possible Applications in the Endocrine and Metabolic Disorder Area.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 13068, doi. 10.3390/ijms222313068
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- Article
Suppression of Pyruvate Dehydrogenase Kinase by Dichloroacetate in Cancer and Skeletal Muscle Cells Is Isoform Specific and Partially Independent of HIF-1α.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8610, doi. 10.3390/ijms22168610
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- Article
Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 764, doi. 10.3390/ijms22020764
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- Article
Programmed Editing of Rice (Oryza sativa L.) OsSPL16 Gene Using CRISPR/Cas9 Improves Grain Yield by Modulating the Expression of Pyruvate Enzymes and Cell Cycle Proteins.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 249, doi. 10.3390/ijms22010249
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- Article
PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5942, doi. 10.3390/ijms21165942
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- Article
Transcriptional and Metabolic Changes Associated with Phytoglobin Expression during Germination of Barley Seeds.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 8, p. 2796, doi. 10.3390/ijms21082796
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- Publication type:
- Article
Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5500, doi. 10.3390/ijms20215500
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- Article
Anesthesia management for ENT surgery in a child with X‐linked pyruvate kinase deficiency.
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- Pediatric Anesthesia, 2021, v. 31, n. 4, p. 499, doi. 10.1111/pan.14105
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- Article
A mutation in the E2 subunit of the mitochondrial pyruvate dehydrogenase complex in Arabidopsis reduces plant organ size and enhances the accumulation of amino acids and intermediate products of the TCA Cycle.
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- Planta: An International Journal of Plant Biology, 2012, v. 236, n. 2, p. 387, doi. 10.1007/s00425-012-1620-3
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- Article
The structure and evolutionary diversity of the fungal E3-binding protein.
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- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04854-7
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- Publication type:
- Article
Quantum chemistry rules retinoid biology.
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- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04602-x
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- Publication type:
- Article
"Brain propane": Propionate Fuels the Brain in Mice With Brain Energy Deficits.
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- Epilepsy Currents, 2025, v. 25, n. 1, p. 70, doi. 10.1177/15357597241293843
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- Article
Blood-Based Lateral-Flow Immunoassays Dipstick Test for Damaged Mitochondrial Electron Transport Chain in Pyruvate Treated Rats with Combined Blast Exposure and Hemorrhagic Shock.
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- Journal of Clinical Medicine, 2025, v. 14, n. 3, p. 754, doi. 10.3390/jcm14030754
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- Article
Phenylbutyrate increases pyruvate dehydrogenase complex activity in cells harboring a variety of defects.
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- Annals of Clinical & Translational Neurology, 2014, v. 1, n. 7, p. 462, doi. 10.1002/acn3.73
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- Publication type:
- Article
Altered glycolysis results in drug-resistant in clinical tumor therapy.
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- Oncology Letters, 2021, v. 21, n. 5, p. N.PAG, doi. 10.3892/ol.2021.12630
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- Article
Overexpression of Pyruvate Dehydrogenase Kinase-3 Predicts Poor Prognosis in Urothelial Carcinoma.
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- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.749142
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- Article
Downregulation of miR-181b-5p Inhibits the Viability, Migration, and Glycolysis of Gallbladder Cancer by Upregulating PDHX Under Hypoxia.
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- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.683725
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- Article
The Implications of PDK1–4 on Tumor Energy Metabolism, Aggressiveness and Therapy Resistance.
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- Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.583217
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- Article
Editorial: Polarization of cellular immune response in the context of inflammation and cancer.
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- Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1433808
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- Article
The moonlighting activities of dihydrolipoamide dehydrogenase: Biotechnological and biomedical applications.
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- Journal of Molecular Recognition, 2021, v. 34, n. 11, p. 1, doi. 10.1002/jmr.2924
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- Article
Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27287-4
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- Article
Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25570-y
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- Article
From Africa to Antarctica: Exploring the Metabolism of Fish Heart Mitochondria Across a Wide Thermal Range.
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- Frontiers in Physiology, 2019, p. 1, doi. 10.3389/fphys.2019.01220
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- Article
Patulin Alters Insulin Signaling and Metabolic Flexibility in HepG2 and HEK293 Cells.
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- Toxins, 2023, v. 15, n. 4, p. 244, doi. 10.3390/toxins15040244
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- Article
Manifestations of X‐linked pyruvate dehydrogenase complex deficiency in female PDHA1 carriers.
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- European Journal of Neurology, 2024, v. 31, n. 7, p. 1, doi. 10.1111/ene.16283
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- Publication type:
- Article
A comprehensive and systematic analysis of Dihydrolipoamide S-acetyltransferase (DLAT) as a novel prognostic biomarker in pan-cancer and glioma.
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- Oncology Research, 2024, v. 32, n. 12, p. 1903, doi. 10.32604/or.2024.048138
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- Article
Guanidine Hydrochloride-Induced Changes of the E2 Inner Core of the Bacillus stearothermophilus Pyruvate Dehydrogenase Complex1.
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- Journal of Biochemistry, 1998, v. 123, n. 4, p. 564, doi. 10.1093/oxfordjournals.jbchem.a021973
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- Article
Clinical and biochemical characterization of four patients with mutations in ECHS1.
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- Orphanet Journal of Rare Diseases, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13023-015-0290-1
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- Publication type:
- Article
Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase.
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- Orphanet Journal of Rare Diseases, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1172-8-192
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- Article
HIBCH mutations can cause Leigh-like disease with combined deficiency of multiple mitochondrial respiratory chain enzymes and pyruvate dehydrogenase.
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- 2013
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- Publication type:
- journal article
Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation.
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- Clinical Science, 2014, v. 127, n. 5, p. 315, doi. 10.1042/CS20140031
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- Article
Protein complexes in cells by AI‐assisted structural proteomics.
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- Molecular Systems Biology, 2023, v. 19, n. 4, p. 1, doi. 10.15252/msb.202311544
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- Publication type:
- Article