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- Title
Isoniazid Preventive Therapy among Children Living with Tuberculosis Patients: Is It Working? A Mixed-Method Study from Bhopal, India.
- Authors
Singh, Akash Ranjan; Kharate, Atul; Bhat, Prashant; Kokane, Arun M.; Bali, Surya; Sahu, Swaroop; Verma, Manoj; Nagar, Mukesh; Kumar, Ajay M. V.; Kumar, Ajay Mv
- Abstract
<bold>Objective: </bold>We assessed uptake of isoniazid preventive therapy (IPT) among child contacts of smear-positive tuberculosis (TB) patients and its implementation challenges from healthcare providers' and parents' perspectives in Bhopal, India.<bold>Methods: </bold>A mixed-method study design: quantitative phase (review of programme records and house-to-house survey of smear-positive TB patients) followed by qualitative phase (interviews of healthcare providers and parents).<bold>Results: </bold>Of 59 child contacts (<6 years) of 129 index patients, 51 were contacted. Among them, 19 of 51 (37%) were screened for TB and one had TB. Only 11 of 50 (22%) children were started and 10 of 50 (20%) completed IPT. Content analysis of interviews revealed lack of awareness, risk perception among parents, cumbersome screening process, isoniazid stock-outs, inadequate knowledge among healthcare providers and poor programmatic monitoring as main barriers to IPT implementation.<bold>Conclusion: </bold>National TB programme should counsel parents, train healthcare providers, simplify screening procedures, ensure regular drug supply and introduce an indicator to strengthen monitoring and uptake of IPT.
- Subjects
INDIA; TUBERCULOSIS prevention; PREVENTIVE medicine; ISONIAZID; CHILDREN of tuberculosis patients; CHEMOPREVENTION; TUBERCULOSIS; PUBLIC health; GOVERNMENT policy; SPUTUM microbiology; TUBERCULOSIS diagnosis; TUBERCULOSIS transmission; ANTITUBERCULAR agents; PREVENTION of communicable diseases; HEALTH attitudes; HEALTH services accessibility; INTERVIEWING; MEDICAL personnel; NATIONAL health services; PATIENT compliance; QUALITATIVE research; CONTACT tracing; EVALUATION of human services programs; PHARMACODYNAMICS
- Publication
Journal of Tropical Pediatrics, 2017, Vol 63, Issue 4, p274
- ISSN
0142-6338
- Publication type
Academic Journal
- DOI
10.1093/tropej/fmw086